SCOPe 2.07: Domain d4cmpb2: 4cmp B:59-713

Lineage for d4cmpb2 (4cmp B:59-713)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.393: CRISPR-associated endonuclease Cas9/Csn1, Target recognition (REC) lobe [345890] (1 superfamily)
   Mostly helical, complex structure

4. Superfamily d.393.1: CRISPR-associated endonuclease Cas9/Csn1, Target recognition (REC) lobe [345923] (1 family)
   Pfam PF16593, Pfam PF13395

5. Family d.393.1.1: CRISPR-associated endonuclease Cas9/Csn1, Target recognition (REC) lobe [345978] (1 protein)

6. Protein CRISPR-associated endonuclease Cas9/Csn1, REC lobe [346112] (3 species)

7. Species Streptococcus pyogenes [TaxId:301447] [346402] (2 PDB entries)

8. Domain d4cmpb2: 4cmp B:59-713 [345149]
   Other proteins in same PDB: d4cmpa1, d4cmpa2, d4cmpa4, d4cmpb1, d4cmpb3, d4cmpb4
   automated match to d4cmpa3
   complexed with mg, so4

Details for d4cmpb2

PDB Entry: 4cmp, 2.62 Å

PDB Description: Crystal structure of S. pyogenes Cas9

PDB Compounds: (B:) crispr-associated endonuclease cas9/csn1

SCOPe Domain Sequences for d4cmpb2:

Sequence, based on SEQRES records:

>d4cmpb2 d.393.1.1 (B:59-713) CRISPR-associated endonuclease Cas9/Csn1, REC lobe {Streptococcus pyogenes [TaxId: 301447]}
aeatrlkrtarrrytrrknricylqeifsnemakvddsffhrleesflveedkkherhpi
fgnivdevayhekyptiyhlrkklvdstdkadlrliylalahmikfrghfliegdlnpdn
sdvdklfiqlvqtynqlfeenpinasgvdakailsarlsksrrlenliaqlpgekknglf
gnlialslgltpnfksnfdlaedaklqlskdtydddldnllaqigdqyadlflaaknlsd
aillsdilrvnteitkaplsasmikrydehhqdltllkalvrqqlpekykeiffdqskng
yagyidggasqeefykfikpilekmdgteellvklnredllrkqrtfdngsiphqihlge
lhailrrqedfypflkdnrekiekiltfripyyvgplargnsrfawmtrkseetitpwnf
eevvdkgasaqsfiermtnfdknlpnekvlpkhsllyeyftvyneltkvkyvtegmrkpa
flsgeqkkaivdllfktnrkvtvkqlkedyfkkiecfdsveisgvedrfnaslgtyhdll
kiikdkdfldneenediledivltltlfedremieerlktyahlfddkvmkqlkrrrytg
wgrlsrklingirdkqsgktildflksdgfanrnfmqlihddsltfkediqkaqv

Sequence, based on observed residues (ATOM records):

>d4cmpb2 d.393.1.1 (B:59-713) CRISPR-associated endonuclease Cas9/Csn1, REC lobe {Streptococcus pyogenes [TaxId: 301447]}
aeatrlkrtarrrytrrknricylqeifsnemakvddsffhrleehpifgnivdevayhe
kyptiyhlrkklvdstdkadlrliylalahmikfrghfliegdlnpdnsdvdklfiqlvq
tynqlfeenpinasgvdakailsarlsksrrlenliaqlpgekknglfgnlialslgltp
nfksnfdlaedaklqlskdtydddldnllaqigdqyadlflaaknlsdaillsdilrvte
itkaplsasmikrydehhqdltllkalvrqqlpekykeiffdqskngyagyidggasqee
fykfikpilekmdgteellvklnredllrkqrtfdngsiphqihlgelhailrrqedfyp
flkdnrekiekiltfrlpnekvlpkhsllyeyftvyneltkvflsgeqkkaivdllfktn
rkvtvkqlkedyfkfnaslgtyhdllkiikdkdfldneenediledivltltlfedremi
eerlktyahlfddkvmkqlkrrrytgwgrlsrklingirdkgktildflksdgfanrnfm
qlihddsltfkediqkaqv

Timeline for d4cmpb2:

• d4cmpb2 is new in SCOPe 2.07-stable
  
• d4cmpb2 appears in the current release, SCOPe 2.08