Lineage for d1bhsa_ (1bhs A:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2841004Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2841005Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2841375Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

    has additional subdomain(s) that are not in the common domain
  6. 2842552Protein Human estrogenic 17beta-hydroxysteroid dehydrogenase [51772] (1 species)
  7. 2842553Species Human (Homo sapiens) [TaxId:9606] [51773] (22 PDB entries)
    Uniprot P14061
  8. 2842560Domain d1bhsa_: 1bhs A: [29840]

Details for d1bhsa_

PDB Entry: 1bhs (more details), 2.2 Å

PDB Description: human estrogenic 17beta-hydroxysteroid dehydrogenase
PDB Compounds: (A:) 17beta-hydroxysteroid dehydrogenase

SCOPe Domain Sequences for d1bhsa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1bhsa_ c.2.1.2 (A:) Human estrogenic 17beta-hydroxysteroid dehydrogenase {Human (Homo sapiens) [TaxId: 9606]}
artvvlitgcssgiglhlavrlasdpsqsfkvyatlrdlktqgrlweaaralacppgsle
tlqldvrdsksvaaarervtegrvdvlvcnaglgllgplealgedavasvldvnvvgtvr
mlqaflpdmkrrgsgrvlvtgsvgglmglpfndvycaskfaleglceslavlllpfgvhl
sliecgpvhtafmekvlgspeevldrtdihtfhrfyqylahskqvfreaaqnpeevaevf
ltalrapkptlryftterflpllrmrlddpsgsnyvtamhrevf

SCOPe Domain Coordinates for d1bhsa_:

Click to download the PDB-style file with coordinates for d1bhsa_.
(The format of our PDB-style files is described here.)

Timeline for d1bhsa_: