Lineage for d4oq5c1 (4oq5 C:174-320)

  1. Root: SCOPe 2.08
  2. 3021034Class f: Membrane and cell surface proteins and peptides [56835] (69 folds)
  3. 3021035Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
    multi-helical domains of various folds which is thought to unfold in the membrane
  4. 3021129Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families) (S)
    PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain
  5. 3021130Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
    Pfam PF00452
  6. 3021303Protein EAT/MCL-1 (Myeloid cell leukemia sequence 1) [118212] (2 species)
  7. 3021304Species Human (Homo sapiens) [TaxId:9606] [188549] (62 PDB entries)
  8. 3021420Domain d4oq5c1: 4oq5 C:174-320 [240721]
    Other proteins in same PDB: d4oq5a2, d4oq5b2, d4oq5c2, d4oq5d2, d4oq5e2, d4oq5f2
    automated match to d4oq5b_
    complexed with 2uu

Details for d4oq5c1

PDB Entry: 4oq5 (more details), 2.86 Å

PDB Description: Crystal Structure of Human MCL-1 Bound to Inhibitor 4-(4-methylnaphthalen-1-yl)-2-{[(4-phenoxyphenyl)sulfonyl]amino}benzoic acid
PDB Compounds: (C:) Induced myeloid leukemia cell differentiation protein Mcl-1

SCOPe Domain Sequences for d4oq5c1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4oq5c1 f.1.4.1 (C:174-320) EAT/MCL-1 (Myeloid cell leukemia sequence 1) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4oq5c1:

Click to download the PDB-style file with coordinates for d4oq5c1.
(The format of our PDB-style files is described here.)

Timeline for d4oq5c1: