Lineage for d2q7nb1 (2q7n B:12-180)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2315782Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 2315783Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 2315784Family a.26.1.1: Long-chain cytokines [47267] (10 proteins)
  6. 2315842Protein Leukemia inhibitory factor (LIF) [47274] (2 species)
  7. 2315843Species Human (Homo sapiens) [TaxId:9606] [63529] (3 PDB entries)
  8. 2315847Domain d2q7nb1: 2q7n B:12-180 [150094]
    automatically matched to d1pvhb_
    complexed with nag

Details for d2q7nb1

PDB Entry: 2q7n (more details), 4 Å

PDB Description: Crystal structure of Leukemia inhibitory factor in complex with LIF receptor (domains 1-5)
PDB Compounds: (B:) leukemia inhibitory factor

SCOPe Domain Sequences for d2q7nb1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2q7nb1 a.26.1.1 (B:12-180) Leukemia inhibitory factor (LIF) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2q7nb1:

Click to download the PDB-style file with coordinates for d2q7nb1.
(The format of our PDB-style files is described here.)

Timeline for d2q7nb1: