Lineage for Protein: Leukemia inhibitory factor (LIF)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1991436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1991437Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1991438Family a.26.1.1: Long-chain cytokines [47267] (10 protein domains)
  6. 1991495Protein Leukemia inhibitory factor (LIF) [47274] (2 species)

Species:

  1. 1991496Human (Homo sapiens) [TaxId:9606] [63529] (3 PDB entries)
    1. Domain for 1emr:
    2. Domains for 1pvh:
      1. 1991497Domain d1pvhb_: 1pvh B: [95167]
        Other proteins in same PDB: d1pvha1, d1pvha2, d1pvhc1, d1pvhc2
        complexed with iod
      2. 1991498Domain d1pvhd_: 1pvh D: [95170]
        Other proteins in same PDB: d1pvha1, d1pvha2, d1pvhc1, d1pvhc2
        complexed with iod
    3. Domains for 2q7n:
      1. 1991500Domain d2q7nb1: 2q7n B:12-180 [150094]
        automatically matched to d1pvhb_
        complexed with nag
      2. 1991501Domain d2q7nd1: 2q7n D:12-180 [150095]
        automatically matched to d1pvhb_
        complexed with nag
  2. 1991502Mouse (Mus musculus) [TaxId:10090] [47275] (2 PDB entries)
    1. Domain for 1a7m:
      • 1991504Domain d1a7ma_: 1a7m A: [16830]
        mouse-human chimera, residues 48-81 are from human sequence
    2. Domain for 1lki:

More info for Protein Leukemia inhibitory factor (LIF) from a.26.1.1: Long-chain cytokines

Timeline for Protein Leukemia inhibitory factor (LIF) from a.26.1.1: Long-chain cytokines: