Lineage for d1z7ea2 (1z7e A:314-656)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2841004Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2841005Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2841375Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
    has additional subdomain(s) that are not in the common domain
  6. 2842682Protein Polymyxin resistance protein ArnA (PrmI) [117419] (1 species)
    evolved new activities: UDP-glucuronic acid decarboxylase, UDP-4-amino-4-deoxy-L-arabinose formyltransferase
  7. 2842683Species Escherichia coli [TaxId:562] [117420] (8 PDB entries)
    Uniprot P77398
  8. 2842690Domain d1z7ea2: 1z7e A:314-656 [124607]
    Other proteins in same PDB: d1z7ea1, d1z7ea3, d1z7eb1, d1z7eb3, d1z7ec1, d1z7ec3, d1z7ed1, d1z7ed3, d1z7ee1, d1z7ee3, d1z7ef1, d1z7ef3
    complexed with atp, uga
    has additional subdomain(s) that are not in the common domain

Details for d1z7ea2

PDB Entry: 1z7e (more details), 3 Å

PDB Description: Crystal structure of full length ArnA
PDB Compounds: (A:) protein ArnA

SCOPe Domain Sequences for d1z7ea2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1z7ea2 c.2.1.2 (A:314-656) Polymyxin resistance protein ArnA (PrmI) {Escherichia coli [TaxId: 562]}
rrtrvlilgvngfignhlterllredhyevygldigsdaisrflnhphfhfvegdisihs
ewieyhvkkcdvvlplvaiatpieytrnplrvfeldfeenlriirycvkyrkriifpsts
evygmcsdkyfdedhsnlivgpvnkprwiysvskqlldrviwaygekeglqftlfrpfnw
mgprldnlnaarigssraitqlilnlvegspiklidggkqkrcftdirdgiealyriien
agnrcdgeiinignpeneasieelgemllasfekhplrhhfppfagfrvvesssyygkgy
qdvehrkpsirnahrcldwepkidmqetidetldfflrtvdlt

SCOPe Domain Coordinates for d1z7ea2:

Click to download the PDB-style file with coordinates for d1z7ea2.
(The format of our PDB-style files is described here.)

Timeline for d1z7ea2: