SCOPe 2.07: Structural Classification of Proteins

PDB entry 2nvz

View 2nvz on RCSB PDB site
Description: RNA Polymerase II elongation complex with UTP, updated 11/2006
Class: transcription,transferase/DNA-RNA hybrid
Keywords: transcription, mRNA, multiprotein complex, molecular machine, DNA, transcription,transferase/DNA-RNA hybrid complex
Deposited on 2006-11-14, released 2006-12-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 4.3 Å
R-factor: 0.276
AEROSPACI score: -0.01 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: DNA-directed RNA polymerase II largest subunit
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P04050
Domains in SCOPe 2.07: d2nvza1
Chain 'B':
Compound: DNA-directed RNA polymerase II 140 kDa polypeptide
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P08518
Domains in SCOPe 2.07: d2nvzb1
Chain 'C':
Compound: DNA-directed RNA polymerase II 45 kDa polypeptide
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P16370
Domains in SCOPe 2.07: d2nvzc1, d2nvzc2
Chain 'E':
Compound: DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P20434 (Start-214)
Domains in SCOPe 2.07: d2nvze1, d2nvze2
Chain 'F':
Compound: DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P20435
Domains in SCOPe 2.07: d2nvzf1
Chain 'H':
Compound: DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P20436 (Start-145)
Domains in SCOPe 2.07: d2nvzh1
Chain 'I':
Compound: DNA-directed RNA polymerase II subunit 9
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P27999
Domains in SCOPe 2.07: d2nvzi1, d2nvzi2
Chain 'J':
Compound: DNA-directed RNA polymerases I/II/III subunit 10
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P22139 (0-End)
Domains in SCOPe 2.07: d2nvzj1
Chain 'K':
Compound: DNA-directed RNA polymerase II 13.6 kDa polypeptide
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P38902 (0-End)
Domains in SCOPe 2.07: d2nvzk1
Chain 'L':
Compound: DNA-directed RNA polymerases I, II, and III 7.7 kDa polypeptide
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P40422 (Start-69)
Domains in SCOPe 2.07: d2nvzl1
Chain 'N':
Compound: 5'-d(*cp*tp*gp*cp*tp*tp*ap*tp*cp*gp*gp*tp*ap*g)-3'
Chain 'R':
Compound: 5'-r(*ap*up*cp*gp*ap*gp*ap*gp*gp*a)-3'
Chain 'T':
Compound: 28-MER DNA template strand
Heterogens: ZN, MG, UTP

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2nvzA (A:)
mvgqqyssaplrtvkevqfglfspeevraisvakirfpetmdetqtrakigglndprlgs
idrnlkcqtcqegmnecpghfghidlakpvfhvgfiakikkvcecvcmhcgkllldehne
lmrqalaikdskkrfaaiwtlcktkmvcetdvpseddptqlvsrggcgntqptirkdglk
lvgswkkdratgdadepelrvlsteeilnifkhisvkdftslgfnevfsrpewmiltclp
vppppvrpsisfnesqrgeddltfkladilkanisletlehngaphhaieeaesllqfhv
atymdndiagqpqalqksgrpvksirarlkgkegrirgnlmgkrvdfsartvisgdpnle
ldqvgvpksiaktltypevvtpynidrltqlvrngpnehpgakyvirdsgdridlryskr
agdiqlqygwkverhimdndpvlfnrqpslhkmsmmahrvkvipystfrlnlsvtspyna
dfdgdemnlhvpqseetraelsqlcavplqivspqsnkpcmgivqdtlcgirkltlrdtf
ieldqvlnmlywvpdwdgviptpaiikpkplwsgkqilsvaipngihlqrfdegttllsp
kdngmliidgqiifgvvekktvgssngglihvvtrekgpqvcaklfgniqkvvnfwllhn
gfstgigdtiadgptmreitetiaeakkkvldvtkeaqanlltakhgmtlresfednvvr
flneardkagrlaevnlkdlnnvkqmvmagskgsfiniaqmsacvgqqsvegkriafgfv
drtlphfskddyspeskgfvensylrgltpqefffhamggreglidtavktaetgyiqrr
lvkaledimvhydnttrnslgnviqfiygedgmdaahiekqsldtiggsdaafekryrvd
llntdhtldpsllesgseilgdlklqvlldeeykqlvkdrkflrevfvdgeanwplpvni
rriiqnaqqtfhidhtkpsdltikdivlgvkdlqenllvlrgkneiiqnaqrdavtlfcc
llrsrlatrrvlqeyrltkqafdwvlsnieaqflrsvvhpgemvgvlaaqsigepatqmt
lntfhfagvaskkvtsgvprlkeilnvaknmktpsltvylepghaadqeqaklirsaieh
ttlksvtiaseiyydpdprstvipedeeiiqlhfslldeeaeqsfdqqspwllrleldra
amndkdltmgqvgerikqtfkndlfviwsedndekliircrvvrpksldaeteaeedhml
kkientmlenitlrgveniervvmmkydrkvpsptgeyvkepewvletdgvnlsevmtvp
gidptriytnsfidimevlgieagraalykevynviasdgsyvnyrhmallvdvmttqgg
ltsvtrhgfnrsntgalmrcsfeetveilfeagasaelddcrgvsenvilgqmapigtga
fdvmideeslvkympeqkiteiedgqdggvtpysnesglvnadldvkdelmfsplvdsgs
ndamaggftayggadygeatspfgaygeaptspgfgvsspgfsptsptysptspayspts
psysptspsysptspsysptspsysptspsysptspsysptspsysptspsysptspsys
ptspsysptspsysptspsysptspsysptspsysptspaysptspsysptspsysptsp
sysptspsysptspnysptspsysptspgyspgspayspkqdeqkhnenensr