SCOPe 2.08: Species: Human (Homo sapiens) [TaxId: 9606]

Root: SCOPe 2.08
Class a: All alpha proteins [46456] (290 folds)
Fold a.26: 4-helical cytokines [47265] (1 superfamily)
core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
Superfamily a.26.1: 4-helical cytokines [47266] (4 families)
there are two different topoisomers of this fold with different entanglements of the two crossover connections
Family a.26.1.2: Short-chain cytokines [47286] (14 proteins)
Protein Stem cell factor, SCF [47299] (1 species)
forms dimer similar to the M-CSF and Flt3 ligand dimers
Species Human (Homo sapiens) [TaxId:9606] [47300] (3 PDB entries)

Domain(s) for 1exz:
1. Domain d1exza_: 1exz A: [16877]
  complexed with ca, sm, trs
2. Domain d1exzb_: 1exz B: [16878]
  complexed with ca, sm, trs
3. Domain d1exzc_: 1exz C: [16879]
  complexed with ca, sm, trs
4. Domain d1exzd_: 1exz D: [16880]
  complexed with ca, sm, trs
Domain(s) for 1scf:
1. Domain d1scfa_: 1scf A: [16873]
  complexed with 1pe, ca
2. Domain d1scfb_: 1scf B: [16874]
  complexed with 1pe, ca
3. Domain d1scfc_: 1scf C: [16875]
  complexed with 1pe, ca
4. Domain d1scfd_: 1scf D: [16876]
  complexed with 1pe, ca
Domain(s) for 2e9w:
- Domain d2e9wc1: 2e9w C:2-140 [146738]
  automatically matched to d1exzb_
  complexed with nag

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.2 Stem cell factor, SCF:

Species Human (Homo sapiens) [TaxId:9606] from a.26.1.2 Stem cell factor, SCF first appeared (with stable ids) in SCOP 1.55
Species Human (Homo sapiens) [TaxId:9606] from a.26.1.2 Stem cell factor, SCF appears in SCOPe 2.07