Lineage for d7d5ba_ (7d5b A:)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2799129Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2799130Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2802457Family b.50.1.0: automated matches [191552] (1 protein)
    not a true family
  6. 2802458Protein automated matches [190954] (13 species)
    not a true protein
  7. 2802490Species Human (Homo sapiens) [TaxId:9606] [193159] (15 PDB entries)
  8. 2802491Domain d7d5ba_: 7d5b A: [401906]
    Other proteins in same PDB: d7d5bd1, d7d5bd2
    automated match to d3zkqa_
    complexed with 66f, cl, edo, na

Details for d7d5ba_

PDB Entry: 7d5b (more details), 1.31 Å

PDB Description: bace2 xaperone complex with n-{3-[(5r)-3-amino-2,5-dimethyl-1,1-dioxo- 5,6-dihydro-2h-1lambda6,2,4-thiadiazin-5-yl]-4-fluorophenyl}-5- fluoropyridine-2-carboxamide
PDB Compounds: (A:) Beta-secretase 2

SCOPe Domain Sequences for d7d5ba_:

Sequence, based on SEQRES records: (download)

>d7d5ba_ b.50.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
anflamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdter
sstyrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwn
gilglayatlakpsssletffdslvtqanipnvfsmqmcgaglpvagsgtnggslvlggi
epslykgdiwytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqk
vfdavveavaraslipefsdgfwtgsqlacwtnsetpwsyfpkisiylrdenssrsfrit
ilpqlyiqpmmgaglnyecyrfgispstnalvigatvmegfyvifdraqkrvgfaaspca
eiagaavseisgpfstedvasncvp

Sequence, based on observed residues (ATOM records): (download)

>d7d5ba_ b.50.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
anflamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdter
sstyrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwn
gilglayatlakpsssletffdslvtqanipnvfsmqmcgaglnggslvlggiepslykg
diwytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkvfdavve
avaraslipefsdgfwtgsqlacwtntpwsyfpkisiylrdenssrsfritilpqlyiqp
mecyrfgispstnalvigatvmegfyvifdraqkrvgfaaspcaeiagaavseisgpfst
edvasncvp

SCOPe Domain Coordinates for d7d5ba_:

Click to download the PDB-style file with coordinates for d7d5ba_.
(The format of our PDB-style files is described here.)

Timeline for d7d5ba_: