SCOPe 2.08: Domain d6xbzj_: 6xbz J:

Lineage for d6xbzj_ (6xbz J:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d6xbzj_: 6xbz J: [393268]
   Other proteins in same PDB: d6xbzi1, d6xbzi2
   automated match to d1ua2a_
   complexed with ags, mg

Details for d6xbzj_

PDB Entry: 6xbz, 2.8 Å

PDB Description: structure of the human cdk-activating kinase

PDB Compounds: (J:) Cyclin-dependent kinase 7

SCOPe Domain Sequences for d6xbzj_:

Sequence, based on SEQRES records:

>d6xbzj_ d.144.1.7 (J:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kryekldflgegqfatvykardkntnqivaikkiklghrseakdginrtalreikllqel
shpniiglldafghksnislvfdfmetdleviikdnslvltpshikaymlmtlqgleylh
qhwilhrdlkpnnllldengvlkladfglaksfgspnraythqvvtrwyrapellfgarm
ygvgvdmwavgcilaelllrvpflpgdsdldqltrifetlgtpteeqwpdmcslpdyvtf
ksfpgiplhhifsaagddlldliqglflfnpcaritatqalkmkyfsnrpgptpgcqlpr
pnc

Sequence, based on observed residues (ATOM records):

>d6xbzj_ d.144.1.7 (J:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kryekldflgegqfatvykardkntnqivaikkiklakdginrtalreikllqelshpni
iglldafghksnislvfdfmetdleviikdnslvltpshikaymlmtlqgleylhqhwil
hrdlkpnnllldengvlkladfglaksfgspnraythqvvtrwyrapellfgarmygvgv
dmwavgcilaelllrvpflpgdsdldqltrifetlgtpteeqwpdmcslpdyvtfksfpg
iplhhifsaagddlldliqglflfnpcaritatqalkmkyfsnrpgptpgcqlprpnc

Timeline for d6xbzj_:

• d6xbzj_ first appeared in SCOPe 2.07