SCOPe 2.08: Domain d6cznb_: 6czn B:

Lineage for d6cznb_ (6czn B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (107 PDB entries)
   Uniprot P03372 307-551

8. Domain d6cznb_: 6czn B: [366513]
   automated match to d3q95b_
   complexed with fnj; mutant

Details for d6cznb_

PDB Entry: 6czn, 2.5 Å

PDB Description: estrogen receptor alpha ligand binding domain y537s mutant in complex with z2ohtpe and a glucocorticoid receptor-interacting protein 1 nr box ii peptide

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d6cznb_:

Sequence, based on SEQRES records:

>d6cznb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdlllemld
ahr

Sequence, based on observed residues (ATOM records):

>d6cznb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseyfseasmmglltnladrelvhminwakrvpgfvdl
tlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdmlla
tssrfrmmnlqgeefvclksiillnsgvytkdhihrvldkitdtlihlmakagltlqqqh
qrlaqlllilshirhmsnkgmehlysmkplsdlllemldahr

Timeline for d6cznb_:

• d6cznb_ first appeared in SCOPe 2.07