SCOPe 2.08: Domain d6mxea1: 6mxe A:155-335

Lineage for d6mxea1 (6mxe A:155-335)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.387: STING C-terminal-like [254119] (1 superfamily)
   5 helices and 5 strands in one mixed beta-sheet, one long bent helix

4. Superfamily d.387.1: STING, TM173 CTD-like [254144] (2 families)
   Pfam PF15009, PubMed 22579474

5. Family d.387.1.1: Tyrosinase cofactor MelC1 [254191] (2 proteins)

6. Protein Tyrosinase cofactor MelC1 [254420] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [254863] (48 PDB entries)

8. Domain d6mxea1: 6mxe A:155-335 [361519]
   Other proteins in same PDB: d6mxea2, d6mxeb2
   automated match to d4f5wa_
   complexed with ca, k5s

Details for d6mxea1

PDB Entry: 6mxe, 2.47 Å

PDB Description: crystal structure of human sting (g230a, h232r, r293q) in complex with compound 18

PDB Compounds: (A:) Stimulator of interferon genes protein

SCOPe Domain Sequences for d6mxea1:

Sequence, based on SEQRES records:

>d6mxea1 d.387.1.1 (A:155-335) Tyrosinase cofactor MelC1 {Human (Homo sapiens) [TaxId: 9606]}
vahglawsyyigylrlilpelqarirtynqhynnllrgavsqrlyillpldcgvpdnlsm
adpnirfldklpqqtadragikdrvysnsiyellengqragtcvleyatplqtlfamsqy
sqagfsredrleqaklfcqtlediladapesqnncrliayqepaddssfslsqevlrhlr
q

Sequence, based on observed residues (ATOM records):

>d6mxea1 d.387.1.1 (A:155-335) Tyrosinase cofactor MelC1 {Human (Homo sapiens) [TaxId: 9606]}
vahglawsyyigylrlilpelqarirtynqhynnllrgavsqrlyillpldcgvpdnlsm
adpnirfldklpqsnsiyellengqragtcvleyatplqtlfamsqysqagfsredrleq
aklfcqtlediladapesqnncrliayqesfslsqevlrhlrq

Timeline for d6mxea1:

• d6mxea1 first appeared in SCOPe 2.07