SCOPe 2.08: Domain d5fxra1: 5fxr A:980-1283

Lineage for d5fxra1 (5fxr A:980-1283)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d5fxra1: 5fxr A:980-1283 [324185]
   Other proteins in same PDB: d5fxra2
   automated match to d1p4ob_
   complexed with 8ln

Details for d5fxra1

PDB Entry: 5fxr, 2.4 Å

PDB Description: igfr-1r complex with a pyrimidine inhibitor.

PDB Compounds: (A:) insulin-like growth factor 1 receptor

SCOPe Domain Sequences for d5fxra1:

Sequence, based on SEQRES records:

>d5fxra1 d.144.1.7 (A:980-1283) automated matches {Human (Homo sapiens) [TaxId: 9606]}
yfsaadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaa
smrerieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpeme
nnpvlappslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrd
iyetdyyrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsne
qvlrfvmegglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsf
yyse

Sequence, based on observed residues (ATOM records):

>d5fxra1 d.144.1.7 (A:980-1283) automated matches {Human (Homo sapiens) [TaxId: 9606]}
yfsadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktveaasm
rerieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemenn
pvlappslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiy
etdyyrkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrf
vmegglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyse

Timeline for d5fxra1:

• d5fxra1 first appeared in SCOPe 2.06
  
• d5fxra1 appears in SCOPe 2.07