PDB entry 5fxr

View 5fxr on RCSB PDB site
Description: IGFR-1R complex with a pyrimidine inhibitor.
Class: transferase
Keywords: transferase
Deposited on 2016-03-02, released 2016-10-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-07-11, with a file datestamp of 2018-07-06.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: insulin-like growth factor 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08069 (1-End)
      • expression tag (0)
    Domains in SCOPe 2.08: d5fxra1, d5fxra2
  • Heterogens: 8LN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5fxrA (A:)
gyfsaadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvnea
asmrerieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpem
ennpvlappslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtr
diyetdyyrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsn
eqvlrfvmegglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevs
fyyseenk

    Sequence, based on observed residues (ATOM records): (download) 
    >5fxrA (A:)
gyfsadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktveaas
mrerieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemen
npvlappslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdi
yetdyyrkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlr
fvmegglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyse