SCOPe 2.08: Domain d3os8c_: 3os8 C:

Lineage for d3os8c_ (3os8 C:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (107 PDB entries)
   Uniprot P03372 307-551

8. Domain d3os8c_: 3os8 C: [183255]
   automated match to d1qkua_
   complexed with kn0

Details for d3os8c_

PDB Entry: 3os8, 2.03 Å

PDB Description: estrogen receptor

PDB Compounds: (C:) Estrogen receptor

SCOPe Domain Sequences for d3os8c_:

Sequence, based on SEQRES records:

>d3os8c_ a.123.1.1 (C:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltrhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvpsydllleml
da

Sequence, based on observed residues (ATOM records):

>d3os8c_ a.123.1.1 (C:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydsmmglltnladrelvhminwakrvpgfvdltr
hdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdmllats
srfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtlihlmak
agltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvpsydlllemlda

Timeline for d3os8c_:

• d3os8c_ first appeared in SCOPe 2.01
  
• d3os8c_ appears in SCOPe 2.07