PDB entry 3os8

View 3os8 on RCSB PDB site
Description: Estrogen Receptor
Class: signaling protein
Keywords: Estrogen Receptor complex, SIGNALING PROTEIN
Deposited on 2010-09-08, released 2010-11-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-11-10, with a file datestamp of 2010-11-05.
Experiment type: XRAY
Resolution: 2.03 Å
R-factor: 0.188
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR1, ESR, NR3A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03372
      • engineered (76)
      • engineered (240)
    Domains in SCOPe 2.08: d3os8a_
  • Chain 'B':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR1, ESR, NR3A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03372
      • engineered (76)
      • engineered (240)
    Domains in SCOPe 2.08: d3os8b_
  • Chain 'C':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR1, ESR, NR3A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03372
      • engineered (76)
      • engineered (240)
    Domains in SCOPe 2.08: d3os8c_
  • Chain 'D':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR1, ESR, NR3A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03372
      • engineered (76)
      • engineered (240)
    Domains in SCOPe 2.08: d3os8d_
  • Heterogens: KN0, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3os8A (A:)
snakrskknslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelv
hminwakrvpgfvdltrhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqg
kcvegmveifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhi
hrvldkitdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvp
sydlllemldahrlhapt

    Sequence, based on observed residues (ATOM records): (download) 
    >3os8A (A:)
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltrhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvpsydlllemld
a

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3os8B (B:)
snakrskknslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelv
hminwakrvpgfvdltrhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqg
kcvegmveifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhi
hrvldkitdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvp
sydlllemldahrlhapt

    Sequence, based on observed residues (ATOM records): (download) 
    >3os8B (B:)
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltrhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvpsydlllemld
a

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3os8C (C:)
snakrskknslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelv
hminwakrvpgfvdltrhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqg
kcvegmveifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhi
hrvldkitdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvp
sydlllemldahrlhapt

    Sequence, based on observed residues (ATOM records): (download) 
    >3os8C (C:)
slalsltadqmvsalldaeppilyseydsmmglltnladrelvhminwakrvpgfvdltr
hdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdmllats
srfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtlihlmak
agltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvpsydlllemlda

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3os8D (D:)
snakrskknslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelv
hminwakrvpgfvdltrhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqg
kcvegmveifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhi
hrvldkitdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvp
sydlllemldahrlhapt

    Sequence, based on observed residues (ATOM records): (download) 
    >3os8D (D:)
slalsltadqmvsalldaeppilyseydsmmglltnladrelvhminwakrvpgfvdltr
hdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdmllats
srfrmmnlqgeefvclksiillnsgvytfksleekdhihrvldkitdtlihlmakagltl
qqqhqrlaqlllilshirhmsnkgmehlysmkcknvvpsydlllemldah