PDB entry 5u16

View 5u16 on RCSB PDB site
Description: Structure of human MR1-2-OH-1-NA in complex with human MAIT A-F7 TCR
Class: immune system
Keywords: T-cell Receptor, IMMUNE SYSTEM
Deposited on 2016-11-27, released 2017-02-15
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-02-15, with a file datestamp of 2017-02-10.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-End)
      • initiating methionine (0)
      • conflict (261)
    Domains in SCOPe 2.06: d5u16a1, d5u16a2, d5u16a3
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5u16b_
  • Chain 'C':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-End)
      • conflict (261)
    Domains in SCOPe 2.06: d5u16c1, d5u16c2
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5u16d_
  • Chain 'E':
    Compound: MAIT T-cell receptor alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRAV/TRAC
    Database cross-references and differences (RAF-indexed):
    • PDB 5U16 (0-End)
    Domains in SCOPe 2.06: d5u16e1, d5u16e2
  • Chain 'F':
    Compound: MAIT T-cell receptor beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRBV/TRBC
    Database cross-references and differences (RAF-indexed):
    • PDB 5U16
    Domains in SCOPe 2.06: d5u16f1, d5u16f2
  • Chain 'G':
    Compound: MAIT T-cell receptor alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRAV/TRAC
    Database cross-references and differences (RAF-indexed):
    • PDB 5U16 (0-End)
    Domains in SCOPe 2.06: d5u16g1, d5u16g2
  • Chain 'H':
    Compound: MAIT T-cell receptor beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRBV/TRBC
    Database cross-references and differences (RAF-indexed):
    • PDB 5U16 (0-End)
    Domains in SCOPe 2.06: d5u16h1, d5u16h2
  • Heterogens: 7WO, GOL, CL, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5u16A (A:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
awasieldpqssnlyschvehsgvhmvlqvp

    Sequence, based on observed residues (ATOM records): (download) 
    >5u16A (A:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrkvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyqawasi
eldpqssnlyschvehsgvhmvlqv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5u16B (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >5u16B (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5u16C (C:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
awasieldpqssnlyschvehsgvhmvlqvp

    Sequence, based on observed residues (ATOM records): (download) 
    >5u16C (C:)
rthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhwe
rytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdfl
ifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrte
pplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyqa
wasieldplyschvehsgvhmvlqv

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5u16D (D:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5u16E (E:)
gqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrf
ssflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavyq
lrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdf
acanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >5u16E (E:)
gqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrf
ssflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavyq
lrdsvclftdfdsqtnvsqsdvyitdkcvldmrsmdfksnsavawsnacanafnnsiipe
dtffp

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5u16F (F:)
nagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgev
pngynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlkn
vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
wgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >5u16F (F:)
gvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgevpn
gynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlknvf
ppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqp
alndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5u16G (G:)
gqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrf
ssflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavyq
lrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdf
acanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >5u16G (G:)
gqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrf
ssflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavyq
lrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdf
acanafnnsiipedtffpsp

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5u16H (H:)
nagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgev
pngynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlkn
vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
wgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >5u16H (H:)
nagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgev
pngynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlkn
vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
wgr