PDB entry 2qlv

View 2qlv on RCSB PDB site
Description: Crystal structure of the heterotrimer core of the S. cerevisiae AMPK homolog SNF1
Class: Transferase/Protein binding
Keywords: heterotrimer, ATP-binding, Carbohydrate metabolism, Kinase, Membrane, Nucleotide-binding, Nucleus, Phosphorylation, Serine/threonine-protein kinase, Transferase, Lipoprotein, Myristate, CBS domain, Transcription, Transcription regulation, Transferase/Protein binding COMPLEX
Deposited on 2007-07-13, released 2007-09-25
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.239
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbon catabolite derepressing protein kinase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: SNF1, CAT1, CCR1, GLC2, PAS14
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2qlva1
  • Chain 'B':
    Compound: Protein SIP2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: SIP2, SPM2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2qlvb1, d2qlvb2
  • Chain 'C':
    Compound: Nuclear protein SNF4
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: SNF4, CAT3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2qlvc1, d2qlvc2
  • Chain 'D':
    Compound: Carbon catabolite derepressing protein kinase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: SNF1, CAT1, CCR1, GLC2, PAS14
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2qlvd_
  • Chain 'E':
    Compound: Protein SIP2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: SIP2, SPM2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2qlve1, d2qlve2
  • Chain 'F':
    Compound: Nuclear protein SNF4
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: SNF4, CAT3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2qlvf1, d2qlvf2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qlvA (A:)
ykeedstvsilptslpqihranmlaqgspaaskisplvtkksktrwhfgirsrsypldvm
geiyialknlgaewakpseedlwtiklrwkydignktntnekipdlmkmviqlfqietnn
ylvdfkfdgwessygddttvsnisedemstfsaypflhlttklimelavns

    Sequence, based on observed residues (ATOM records): (download) 
    >2qlvA (A:)
ykeedstvsilptslpqihranmlaqgspaaskisplvttrwhfgirsrsypldvmgeiy
ialknlgaewakpslwtiklrwkdlmkmviqlfqnnylvdfkfdgwesemstfsaypflh
lttklimelavns

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2qlvB (B:)
slmvpveirwqqggskvyvtgsftkwrkmiglipdsdnngsfhvklrllpgthrfrfivd
nelrvsdflptatdqmgnfvnyievrqpeknptnekirskeadsmrpptsdrssialqig
kdpddfgdgytrfhedlsprppleyttdipavftdpsvmeryyytldrqqsntdtswltp
pqlppqlenvilnkyyatqdqfnennsgalpipnhvvlnhlvtssikhntlcvasivryk
qkyvtqilytpi

    Sequence, based on observed residues (ATOM records): (download) 
    >2qlvB (B:)
slmvpveirwqqggskvyvtgsftkwrkmiglipdsdnngsfhvklrllpgthrfrfivd
nelrvsdflptatdqmgnfvnyievrqttdipavftdpsvmeryyytldrppqlppqhvv
lnhlvtssikhntlcvasivrykqkyvtqilytpi

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2qlvC (C:)
sqekvsieqqlavesirkflnsktsydvlpvsyrlivldtsllvkkslnvllqnsivsap
lwdsktsrfaglltttdfinviqyyfsnpdkfelvdklqldglkdieralgvdqldtasi
hpsrplfeaclkmlesrsgriplidqdeethreivvsvltqyrilkfvalncrethflki
pigdlniitqdnmkscqmttpvidviqmltqgrvssvpiidengylinvyeaydvlglik
ggiyndlslsvgealmrrsddfegvytctkndklstimdnirkarvhrffvvddvgrlvg
vltlsdilkyillgs

    Sequence, based on observed residues (ATOM records): (download) 
    >2qlvC (C:)
sqekvsieqqlavesirkflnsktsydvlpvsyrlivldtsllvkkslnvllqnsivsap
lwdsktsrfaglltttdfinviqyyfsnpdkfelvdklqldglkdieralgvdqldtasi
hpsrplfeaclkmlesrsgriplidqreivvsvltqyrilkfvalncrethflkipigdl
niitqdnmkscqmttpvidviqmltqgrvssvpiidengylinvyeaydvlglikggiyn
dlslsvgealmrrsddfegvytctkndklstimdnirkarvhrffvvddvgrlvgvltls
dilkyillgs

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2qlvD (D:)
ykeedstvsilptslpqihranmlaqgspaaskisplvtkksktrwhfgirsrsypldvm
geiyialknlgaewakpseedlwtiklrwkydignktntnekipdlmkmviqlfqietnn
ylvdfkfdgwessygddttvsnisedemstfsaypflhlttklimelavns

    Sequence, based on observed residues (ATOM records): (download) 
    >2qlvD (D:)
ykeedstvsilptslpqihranmlaqgspaaskisplvttrwhfgirsrsypldvmgeiy
ialknlgaewakpslwtiklrwkdlmkmviqlfqnnylvdfkfdgwesemstfsaypflh
lttklimelavns

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2qlvE (E:)
slmvpveirwqqggskvyvtgsftkwrkmiglipdsdnngsfhvklrllpgthrfrfivd
nelrvsdflptatdqmgnfvnyievrqpeknptnekirskeadsmrpptsdrssialqig
kdpddfgdgytrfhedlsprppleyttdipavftdpsvmeryyytldrqqsntdtswltp
pqlppqlenvilnkyyatqdqfnennsgalpipnhvvlnhlvtssikhntlcvasivryk
qkyvtqilytpi

    Sequence, based on observed residues (ATOM records): (download) 
    >2qlvE (E:)
slmvpveirwqqggskvyvtgsftkwrkmiglipdsdnngsfhvklrllpgthrfrfivd
nelrvsdflptatdqmgnfvnyievrqtdipavftppqlppqhvvlnhlvtssikhntlc
vasivrykqkyvtqilytpi

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2qlvF (F:)
sqekvsieqqlavesirkflnsktsydvlpvsyrlivldtsllvkkslnvllqnsivsap
lwdsktsrfaglltttdfinviqyyfsnpdkfelvdklqldglkdieralgvdqldtasi
hpsrplfeaclkmlesrsgriplidqdeethreivvsvltqyrilkfvalncrethflki
pigdlniitqdnmkscqmttpvidviqmltqgrvssvpiidengylinvyeaydvlglik
ggiyndlslsvgealmrrsddfegvytctkndklstimdnirkarvhrffvvddvgrlvg
vltlsdilkyillgs

    Sequence, based on observed residues (ATOM records): (download) 
    >2qlvF (F:)
sqekvsieqqlavesirkflnsktsydvlpvsyrlivldtsllvkkslnvllqnsivsap
lwdsktsrfaglltttdfinviqyyfsnpdkfelvdklqldglkdieralgvdqldtasi
hpsrplfeaclkmlesrsgriplidqreivvsvltqyrilkfvalncrethflkipigdl
niitqdnmkscqmttpvidviqmltqgrvssvpiidengylinvyeaydvlglikggiyn
dlslsvgealmrrsddfegvytctkndklstimdnirkarvhrffvvddvgrlvgvltls
dilkyillgs