SCOPe 2.08: Domain d1q3hc1: 1q3h C:389-670

Lineage for d1q3hc1 (1q3h C:389-670)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.12: ABC transporter ATPase domain-like [52686] (25 proteins)
   there are two additional subdomains inserted into the central core that has a RecA-like topology
   missing some secondary structures that made up less than one-third of the common domain
   

6. Protein Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain [102378] (2 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [102379] (9 PDB entries)
   Uniprot P26361 390-670

8. Domain d1q3hc1: 1q3h C:389-670 [95690]
   Other proteins in same PDB: d1q3hc2
   complexed with acy, anp, mg

Details for d1q3hc1

PDB Entry: 1q3h, 2.5 Å

PDB Description: mouse cftr nbd1 with amp.pnp

PDB Compounds: (C:) Cystic fibrosis transmembrane conductance regulator

SCOPe Domain Sequences for d1q3hc1:

Sequence, based on SEQRES records:

>d1q3hc1 c.37.1.12 (C:389-670) Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain {Mouse (Mus musculus) [TaxId: 10090]}
ttgiimenvtafweegfgellekvqqsngdrkhssdennvsfshlclvgnpvlkninlni
ekgemlaitgstgsgktsllmlilgeleasegiikhsgrvsfcsqfswimpgtikeniif
gvsydeyryksvvkacqlqqditkfaeqdntvlgeggvtlsggqrarislaravykdadl
ylldspfgyldvfteeqvfescvcklmanktrilvtskmehlrkadkililhqgssyfyg
tfselqslrpdfssklmgydtfdqfteerrssiltetlrrfs

Sequence, based on observed residues (ATOM records):

>d1q3hc1 c.37.1.12 (C:389-670) Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain {Mouse (Mus musculus) [TaxId: 10090]}
ttgiimenvtafweegfgellekvfshlclvgnpvlkninlniekgemlaitgstgsgkt
sllmlilgeleasegiikhsgrvsfcsqfswimpgtikeniifgvsydeyryksvvkacq
lqqditkfaeqdntvlgeggvtlsggqrarislaravykdadlylldspfgyldvfteeq
vfescvcklmanktrilvtskmehlrkadkililhqgssyfygtfselqslrpdfssklm
gydtfdqfteerrssiltetlrrfs

Timeline for d1q3hc1:

• d1q3hc1 first appeared in SCOP 1.67, called d1q3hc_
  
• d1q3hc1 appears in SCOPe 2.07