Lineage for Family c.37.1.12: ABC transporter ATPase domain-like

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2109203Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2109204Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2112785Family c.37.1.12: ABC transporter ATPase domain-like [52686] (25 protein domains)
    there are two additional subdomains inserted into the central core that has a RecA-like topology

Protein Domains:

  1. 2112786ABC transporter involved in vitamin B12 uptake, BtuD [75209] (1 species)
  2. 2112792ATP-binding subunit of the histidine permease [52687] (1 species)
  3. 2112795Branched chain aminoacid ABC transporter [75207] (1 species)
  4. 2112798Cell division protein MukB [52695] (1 species)
  5. 2112801Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain [102378] (2 species)
    1. 2112802Species Human (Homo sapiens) [TaxId:9606] [117543] (9 PDB entries)
      Uniprot P13569 389-671
    2. 2112821Species Mouse (Mus musculus) [TaxId:10090] [102379] (9 PDB entries)
      Uniprot P26361 390-670
  6. 2112854DNA repair protein MutS, the C-terminal domain [52697] (2 species)
    1. 2112855Species Escherichia coli [TaxId:562] [52699] (8 PDB entries)
      Uniprot P23909 2-800
    2. 2112871Species Thermus aquaticus [TaxId:271] [52698] (4 PDB entries)
  7. 2112880Glucose transport protein GlcV, N-terminal domain [89681] (1 species)
  8. 2112893Haemolysin B ATP-binding protein [89683] (1 species)
  9. 2112898Hypothetical protein PH0022, N-terminal domain [117546] (1 species)
  10. 2112902Maltose transport protein MalK, N-terminal domain [52689] (2 species)
    1. 2112903Species Escherichia coli [TaxId:562] [102380] (15 PDB entries)
    2. 2112942Species Thermococcus litoralis [TaxId:2265] [52690] (1 PDB entry)
  11. 2112945Methionine import ATP-binding protein MetN [159571] (1 species)
  12. 2112951MJ0796 [64027] (1 species)
  13. 2112956MJ1267 [64025] (1 species)
  14. 2112963Molybdate/tungstate import ATP-binding protein WtpC (ModC) [159569] (1 species)
  15. 2112966Multidrug resistance ABC transporter LmrA, C-terminal domain [102381] (1 species)
  16. 2112972Multidrug resistance ABC transporter MsbA, C-terminal domain [89685] (1 species)
    a low-resolution structure of the E. coli MsbA in an open conformation is also available (f.35.1.1)
  17. 2112986P-glycoprotein (P-gp) multidrug resistance protein, head domain [310790] (2 species)
    Pfam PF09818
    1. 2112987Species Mouse (Mus musculus) [TaxId:10090] [311047] (1 PDB entry)
    2. 2112990Species Streptococcus pneumoniae TIGR4 [TaxId:170187] [311048] (1 PDB entry)
  18. 2112992Peptide transporter Tap1, C-terminal ABC domain [64029] (1 species)
  19. 2112995Putative ABC transporter PF0895 [110560] (1 species)
  20. 2112998Putative ABC transporter TM0544 [117548] (1 species)
  21. 2113001Putative multidrug export ATP-binding/permease protein SAV1866 [142303] (2 species)
    1. 2113002Species Human (Homo sapiens) [TaxId:9606] [224888] (1 PDB entry)
    2. 2113007Species Staphylococcus aureus [TaxId:1280] [142304] (2 PDB entries)
      Uniprot Q99T13 324-578
  22. 2113012Rad50 [52691] (1 species)
  23. 2113019Smc head domain [52693] (3 species)
    1. 2113020Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [117544] (1 PDB entry)
      Uniprot P32908 2-214,1024-1223
    2. 2113025Species Pyrococcus furiosus [TaxId:2261] [117545] (2 PDB entries)
      Uniprot Q877I1 1-167,1012-1173
    3. 2113028Species Thermotoga maritima [TaxId:2336] [52694] (1 PDB entry)
  24. 2113035Sulfate/molybdate ABC transporter, ATP-binding protein [159573] (1 species)
  25. 2113038automated matches [190723] (8 species)
    not a true protein
    1. 2113039Species Archaeoglobus fulgidus [TaxId:2234] [255529] (1 PDB entry)
    2. 2113043Species Escherichia coli K-12 [TaxId:83333] [233742] (1 PDB entry)
    3. 2113048Species Escherichia coli [TaxId:83333] [261141] (1 PDB entry)
    4. 2113051Species Methanocaldococcus jannaschii [TaxId:243232] [195767] (1 PDB entry)
    5. Species Methanosarcina acetivorans [TaxId:2214] [255793] (1 PDB entry)
    6. 2113056Species Norway rat (Rattus norvegicus) [TaxId:10116] [187882] (4 PDB entries)
    7. 2113065Species Pyrococcus horikoshii [TaxId:53953] [255107] (1 PDB entry)
    8. 2113067Species Streptococcus pneumoniae [TaxId:170187] [311250] (2 PDB entries)

More info for Family c.37.1.12: ABC transporter ATPase domain-like

Timeline for Family c.37.1.12: ABC transporter ATPase domain-like: