SCOPe 2.08: Family c.37.1.12: ABC transporter ATPase domain-like

Lineage for Family c.37.1.12: ABC transporter ATPase domain-like

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.12: ABC transporter ATPase domain-like [52686] (25 proteins)
   there are two additional subdomains inserted into the central core that has a RecA-like topology
   missing some secondary structures that made up less than one-third of the common domain
   

Proteins:

1. ABC transporter involved in vitamin B12 uptake, BtuD [75209] (1 species)

   • Species Escherichia coli [TaxId:562] [75210] (2 PDB entries)

2. ATP-binding subunit of the histidine permease [52687] (1 species)

   • Species Salmonella typhimurium [TaxId:90371] [52688] (1 PDB entry)

3. Branched chain aminoacid ABC transporter [75207] (1 species)

   • Species Thermotoga maritima, TM1139 [TaxId:2336] [75208] (1 PDB entry)

4. Cell division protein MukB [52695] (1 species)

   • Species Escherichia coli [TaxId:562] [52696] (1 PDB entry)

5. Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain [102378] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [117543] (26 PDB entries)
      Uniprot P13569 389-671

   2. Species Mouse (Mus musculus) [TaxId:10090] [102379] (9 PDB entries)
      Uniprot P26361 390-670

6. DNA repair protein MutS, the C-terminal domain [52697] (2 species)

   1. Species Escherichia coli [TaxId:562] [52699] (8 PDB entries)
      Uniprot P23909 2-800

   2. Species Thermus aquaticus [TaxId:271] [52698] (4 PDB entries)

7. Glucose transport protein GlcV, N-terminal domain [89681] (1 species)

   • Species Sulfolobus solfataricus [TaxId:2287] [89682] (5 PDB entries)

8. Haemolysin B ATP-binding protein [89683] (1 species)

   • Species Escherichia coli [TaxId:562] [89684] (3 PDB entries)

9. Hypothetical protein PH0022, N-terminal domain [117546] (1 species)

   • Species Pyrococcus horikoshii [TaxId:53953] [117547] (2 PDB entries)
     Uniprot O57758

10. Maltose transport protein MalK, N-terminal domain [52689] (2 species)

    1. Species Escherichia coli [TaxId:562] [102380] (15 PDB entries)

    2. Species Thermococcus litoralis [TaxId:2265] [52690] (1 PDB entry)

11. Methionine import ATP-binding protein MetN [159571] (1 species)

    • Species Escherichia coli [TaxId:562] [159572] (2 PDB entries)
      Uniprot P30750 1-240

12. MJ0796 [64027] (1 species)

    • Species Methanococcus jannaschii [TaxId:2190] [64028] (2 PDB entries)

13. MJ1267 [64025] (1 species)

    • Species Methanococcus jannaschii [TaxId:2190] [64026] (3 PDB entries)

14. Molybdate/tungstate import ATP-binding protein WtpC (ModC) [159569] (1 species)

    • Species Archaeoglobus fulgidus [TaxId:2234] [159570] (1 PDB entry)
      Uniprot O30144 1-240

15. Multidrug resistance ABC transporter LmrA, C-terminal domain [102381] (1 species)

    • Species Lactococcus lactis [TaxId:1358] [102382] (1 PDB entry)

16. Multidrug resistance ABC transporter MsbA, C-terminal domain [89685] (1 species)
    a low-resolution structure of the E. coli MsbA in an open conformation is also available (f.35.1.1)

    • Species Salmonella typhimurium [TaxId:90371] [159568] (3 PDB entries)
      Uniprot P63359 329-581

17. P-glycoprotein (P-gp) multidrug resistance protein, head domain [310790] (2 species)
    Pfam PF09818

    1. Species Mouse (Mus musculus) [TaxId:10090] [311047] (1 PDB entry)

    2. Species Streptococcus pneumoniae TIGR4 [TaxId:170187] [311048] (1 PDB entry)

18. Peptide transporter Tap1, C-terminal ABC domain [64029] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [64030] (1 PDB entry)

19. Putative ABC transporter PF0895 [110560] (1 species)

    • Species Pyrococcus furiosus [TaxId:2261] [110561] (1 PDB entry)
      Uniprot Q8U2E3

20. Putative ABC transporter TM0544 [117548] (1 species)

    • Species Thermotoga maritima [TaxId:2336] [117549] (1 PDB entry)
      Uniprot Q9WZ14

21. Putative multidrug export ATP-binding/permease protein SAV1866 [142303] (2 species)

    1. Species Human (Homo sapiens) [TaxId:9606] [224888] (1 PDB entry)

    2. Species Staphylococcus aureus [TaxId:1280] [142304] (2 PDB entries)
       Uniprot Q99T13 324-578

22. Rad50 [52691] (1 species)

    • Species Pyrococcus furiosus [TaxId:2261] [52692] (4 PDB entries)

23. Smc head domain [52693] (3 species)

    1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [117544] (1 PDB entry)
       Uniprot P32908 2-214,1024-1223

    2. Species Pyrococcus furiosus [TaxId:2261] [117545] (2 PDB entries)
       Uniprot Q877I1 1-167,1012-1173

    3. Species Thermotoga maritima [TaxId:2336] [52694] (1 PDB entry)

24. Sulfate/molybdate ABC transporter, ATP-binding protein [159573] (1 species)

    • Species Methanosarcina acetivorans [TaxId:2214] [159574] (1 PDB entry)
      Uniprot Q8TTZ3 1-229

25. automated matches [190723] (8 species)
    not a true protein

    1. Species Archaeoglobus fulgidus [TaxId:2234] [255529] (1 PDB entry)

    2. Species Escherichia coli K-12 [TaxId:83333] [233742] (1 PDB entry)

    3. Species Escherichia coli [TaxId:83333] [261141] (1 PDB entry)

    4. Species Methanocaldococcus jannaschii [TaxId:243232] [195767] (1 PDB entry)

    5. Species Methanosarcina acetivorans [TaxId:2214] [255793] (1 PDB entry)

    6. Species Norway rat (Rattus norvegicus) [TaxId:10116] [187882] (4 PDB entries)

    7. Species Pyrococcus horikoshii [TaxId:53953] [255107] (1 PDB entry)

    8. Species Streptococcus pneumoniae [TaxId:170187] [311250] (2 PDB entries)

More info for Family c.37.1.12: ABC transporter ATPase domain-like

Timeline for Family c.37.1.12: ABC transporter ATPase domain-like:

• Family c.37.1.12: ABC transporter ATPase domain-like first appeared (with stable ids) in SCOP 1.55
  
• Family c.37.1.12: ABC transporter ATPase domain-like appears in SCOPe 2.07