SCOPe 2.01: Domain d1nw9b_: 1nw9 B:

Lineage for d1nw9b_ (1nw9 B:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.17: Caspase-like [52128] (1 superfamily)
   3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest

4. Superfamily c.17.1: Caspase-like [52129] (3 families)
   mature protein may be composed of two chains folded in a single domain

5. Family c.17.1.1: Caspase catalytic domain [52130] (8 proteins)

6. Protein Caspase-9 [69443] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69444] (2 PDB entries)

8. Domain d1nw9b_: 1nw9 B: [86294]
   Other proteins in same PDB: d1nw9a_
   complexed to the xiap-bir3
   complexed with zn

Details for d1nw9b_

PDB Entry: 1nw9, 2.4 Å

PDB Description: structure of caspase-9 in an inhibitory complex with xiap-bir3

PDB Compounds: (B:) caspase 9, apoptosis-related cysteine protease

SCOPe Domain Sequences for d1nw9b_:

Sequence, based on SEQRES records:

>d1nw9b_ c.17.1.1 (B:) Caspase-9 {Human (Homo sapiens) [TaxId: 9606]}
galeslrgnadlayilsmepcghcliinnvnfcresglrtrtgsnidceklrrrfsslhf
mvevkgdltakkmvlallelarqdhgaldccvvvilshgcqashlqfpgavygtdgcpvs
vekivnifngtscpslggkpklffiqacggeqkdhgfevastspedespgsnpepdatpf
qeglrtfdqldaisslptpsdifvsystfpgfvswrdpksgswyvetlddifeqwahsed
lqslllrvanavsvkgiykqmpgcfnflrkklffkts

Sequence, based on observed residues (ATOM records):

>d1nw9b_ c.17.1.1 (B:) Caspase-9 {Human (Homo sapiens) [TaxId: 9606]}
galeslrgnadlayilsmepcghcliinnvnfcresglrtrtgsnidceklrrrfsslhf
mvevkgdltakkmvlallelarqdhgaldccvvvilshgcqashlqfpgavygtdgcpvs
vekivnifngtscpslggkpklffiqacgatpfqsslptpsdifvsystfpgfvswrdpk
sgswyvetlddifeqwahsedlqslllrvanavsvkgiykqmpgcfnflrkklffkts

Timeline for d1nw9b_:

• d1nw9b_ first appeared in SCOP 1.65
  
• d1nw9b_ appears in SCOP 1.75
  
• d1nw9b_ appears in SCOPe 2.02
  
• d1nw9b_ appears in the current release, SCOPe 2.08