PDB entry 1nw9
View 1nw9 on RCSB PDB site
Description: structure of caspase-9 in an inhibitory complex with xiap-bir3
Class: apoptosis
Keywords: caspase-9, XIAP, caspase inhibition, caspase activation, dimerization, apoptosis
Deposited on
2003-02-05, released
2003-03-25
The last revision prior to the SCOPe 2.01 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.23
AEROSPACI score: 0.32
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: baculoviral iap repeat-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: BIRC4 OR API3 OR IAP3 OR XIAP
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d1nw9a_ - Chain 'B':
Compound: caspase 9, apoptosis-related cysteine protease
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d1nw9b_ - Heterogens: ZN
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1nw9A (A:)
stnlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkp
sedpweqhakwypgckylleqkgqeyinnihlthslee
Sequence, based on observed residues (ATOM records): (download)
>1nw9A (A:)
lprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkpsed
pweqhakwypgckylleqkgqeyinnihlth
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1nw9B (B:)
galeslrgnadlayilsmepcghcliinnvnfcresglrtrtgsnidceklrrrfsslhf
mvevkgdltakkmvlallelarqdhgaldccvvvilshgcqashlqfpgavygtdgcpvs
vekivnifngtscpslggkpklffiqacggeqkdhgfevastspedespgsnpepdatpf
qeglrtfdqldaisslptpsdifvsystfpgfvswrdpksgswyvetlddifeqwahsed
lqslllrvanavsvkgiykqmpgcfnflrkklffkts
Sequence, based on observed residues (ATOM records): (download)
>1nw9B (B:)
galeslrgnadlayilsmepcghcliinnvnfcresglrtrtgsnidceklrrrfsslhf
mvevkgdltakkmvlallelarqdhgaldccvvvilshgcqashlqfpgavygtdgcpvs
vekivnifngtscpslggkpklffiqacgatpfqsslptpsdifvsystfpgfvswrdpk
sgswyvetlddifeqwahsedlqslllrvanavsvkgiykqmpgcfnflrkklffkts