| Class d: Alpha and beta proteins (a+b) [53931] (376 folds) |
| Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily) consists of two alpha+beta domains, C-terminal domain is mostly alpha helical |
Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) ![]() shares functional and structural similarities with the ATP-grasp fold and PIPK |
| Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins) members organized in the groups and subfamiles specified by the comments |
| Protein EGF receptor tyrosine kinase, Erbb-1 [82795] (1 species) PTK group; EGFR subfamily; membrane spanning protein tyrosine kinase |
| Species Human (Homo sapiens) [TaxId:9606] [82796] (38 PDB entries) Uniprot P00533 702-1018 |
| Domain d1m14a_: 1m14 A: [78367] |
| Domain d1m17a_: 1m17 A: [78370] complexed with aq4 |
| Domain d1xkka_: 1xkk A: [115409] complexed with fmm, po4 |
| Domain d2eb2a_: 2eb2 A: [163929] automated match to d1m14a_ |
| Domain d2eb3a_: 2eb3 A: [163930] automated match to d1m14a_ complexed with anp |
| Domain d2gs2a_: 2gs2 A: [135574] automated match to d1m14a_ |
| Domain d2gs6a_: 2gs6 A: [135578] automated match to d1m14a_ complexed with 112, cl |
| Domain d2gs7a_: 2gs7 A: [164827] automated match to d1m14a_ complexed with anp, iod, mg |
| Domain d2gs7b_: 2gs7 B: [164828] automated match to d1m14a_ complexed with anp, iod, mg |
| Domain d2itya1: 2ity A:697-1018 [137648] automatically matched to d1m14a_ complexed with ire |
| Domain d2j5fa1: 2j5f A:696-1018 [138035] automatically matched to d1m14a_ complexed with djk |
| Domain d2j6ma1: 2j6m A:697-1018 [138088] automatically matched to d1m14a_ complexed with aee |
| Domain d2rfed_: 2rfe D: [168080] automated match to d1m14a_ |
| Domain d2rgpa_: 2rgp A: [206100] automated match to d3gt8b_ complexed with hyz, po4 |
| Domain d3bela_: 3bel A: [208629] automated match to d3gt8b_ complexed with po4, pox |
| Domain d3gt8a_: 3gt8 A: [176980] automated match to d1m14a_ complexed with anp, mg |
| Domain d3gt8b_: 3gt8 B: [176981] automated match to d1m14a_ complexed with anp, mg |
| Domain d3gt8c_: 3gt8 C: [176982] automated match to d1m14a_ complexed with anp, mg |
| Domain d3gt8d_: 3gt8 D: [176983] automated match to d1m14a_ complexed with anp, mg |
| Domain d3ikaa_: 3ika A: [178367] automated match to d1m14a_ complexed with 0un; mutant |
| Domain d3ikab_: 3ika B: [178368] automated match to d1m14a_ complexed with 0un; mutant |
| Domain d3poza_: 3poz A: [183915] automated match to d1m14a_ complexed with 03p, so4 |
| Domain d3ug1a_: 3ug1 A: [195858] automated match to d2gs6a_ complexed with mes |
| Domain d3ug2a_: 3ug2 A: [195859] automated match to d2gs6a_ complexed with ire, mes |
| Domain d3vjna_: 3vjn A: [195851] automated match to d2gs6a_ complexed with anp |
| Domain d3vjoa_: 3vjo A: [195853] automated match to d2gs6a_ complexed with anp |
| Domain d3w2oa_: 3w2o A: [194105] automated match to d1m14a_ complexed with 03p; mutant |
| Domain d3w2pa_: 3w2p A: [194104] automated match to d1m14a_ complexed with w2p; mutant |
| Domain d3w2qa_: 3w2q A: [233922] automated match to d3w2oa_ complexed with hki, mes; mutant |
| Domain d3w2ra_: 3w2r A: [233923] automated match to d3w2oa_ complexed with edo, w2r; mutant |
| Domain d3w2sa_: 3w2s A: [218196] automated match to d2gs6a_ complexed with so4, w2r |
| Domain d3w32a_: 3w32 A: [193901] automated match to d2gs6a_ complexed with so4, w32 |
| Domain d3w33a_: 3w33 A: [193900] automated match to d2gs6a_ complexed with so4, w19 |
| Domain d4hjoa_: 4hjo A: [194321] automated match to d1m14a_ complexed with aq4 |
| Domain d4i22a_: 4i22 A: [194134] automated match to d1m14a_ complexed with ire, so4; mutant |
| Domain d4i23a_: 4i23 A: [194125] automated match to d1m14a_ complexed with 1c9 |
| Domain d4i24a_: 4i24 A: [193289] automated match to d1m14a_ complexed with 1c9 |
| Domain d4i24b_: 4i24 B: [234764] automated match to d4i24a_ complexed with 1c9 |
| Domain d4jq7a_: 4jq7 A: [223939] automated match to d4jq8a_ complexed with kjq |
| Domain d4jq8a_: 4jq8 A: [197414] automated match to d1m14a_ complexed with kj8 |
| Domain d4jr3a_: 4jr3 A: [223948] automated match to d4jq8a_ complexed with kjr |
| Domain d4jrva_: 4jrv A: [223973] automated match to d4jq8a_ complexed with kjv |
| Domain d4li5a_: 4li5 A: [224685] automated match to d2eb2a_ complexed with 1wy, na |
| Domain d4lqma_: 4lqm A: [236055] automated match to d3ikaa_ complexed with cl, djk |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 EGF receptor tyrosine kinase, Erbb-1: