Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2543502Protein EGF receptor tyrosine kinase, Erbb-1 [82795] (1 species)
    PTK group; EGFR subfamily; membrane spanning protein tyrosine kinase
  7. 2543503Species Human (Homo sapiens) [TaxId:9606] [82796] (103 PDB entries)
    Uniprot P00533 702-1018

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1m14:
  2. Domain(s) for 1m17:
  3. Domain(s) for 1xkk:
  4. Domain(s) for 2eb2:
  5. Domain(s) for 2eb3:
  6. Domain(s) for 2gs2:
  7. Domain(s) for 2gs6:
  8. Domain(s) for 2gs7:
    1. 2543545Domain d2gs7a_: 2gs7 A: [164827]
      automated match to d1m14a_
      complexed with anp, iod, mg
    2. 2543546Domain d2gs7b_: 2gs7 B: [164828]
      automated match to d1m14a_
      complexed with anp, iod, mg
  9. Domain(s) for 2ity:
  10. Domain(s) for 2rfe:
  11. Domain(s) for 2rgp:
  12. Domain(s) for 3bel:
  13. Domain(s) for 3gt8:
    1. 2543560Domain d3gt8a_: 3gt8 A: [176980]
      automated match to d1m14a_
      complexed with anp, mg
    2. 2543561Domain d3gt8b_: 3gt8 B: [176981]
      automated match to d1m14a_
      complexed with anp, mg
    3. 2543562Domain d3gt8c_: 3gt8 C: [176982]
      automated match to d1m14a_
      complexed with anp, mg
    4. 2543563Domain d3gt8d_: 3gt8 D: [176983]
      automated match to d1m14a_
      complexed with anp, mg
  14. Domain(s) for 3ika:
    1. 2543564Domain d3ikaa_: 3ika A: [178367]
      automated match to d1m14a_
      complexed with 0un; mutant
    2. 2543565Domain d3ikab_: 3ika B: [178368]
      automated match to d1m14a_
      complexed with 0un; mutant
  15. Domain(s) for 3poz:
  16. Domain(s) for 3ug1:
  17. Domain(s) for 3ug2:
  18. Domain(s) for 3vjn:
  19. Domain(s) for 3vjo:
  20. Domain(s) for 3w2o:
  21. Domain(s) for 3w2p:
  22. Domain(s) for 3w2q:
  23. Domain(s) for 3w2r:
  24. Domain(s) for 3w2s:
  25. Domain(s) for 3w32:
  26. Domain(s) for 3w33:
  27. Domain(s) for 4hjo:
  28. Domain(s) for 4i22:
  29. Domain(s) for 4i23:
  30. Domain(s) for 4i24:
    1. 2543508Domain d4i24a_: 4i24 A: [193289]
      automated match to d1m14a_
      complexed with 1c9
    2. 2543509Domain d4i24b_: 4i24 B: [234764]
      automated match to d4i24a_
      complexed with 1c9
  31. Domain(s) for 4jq7:
  32. Domain(s) for 4jq8:
  33. Domain(s) for 4jr3:
  34. Domain(s) for 4jrv:
  35. Domain(s) for 4li5:
  36. Domain(s) for 4lqm:
  37. Domain(s) for 4r5s:
  38. Domain(s) for 4riw:
    1. 2543600Domain d4riwb_: 4riw B: [261970]
      Other proteins in same PDB: d4riwa_, d4riwc_
      automated match to d3ikaa_
      complexed with adp, anp, mg
    2. 2543601Domain d4riwd_: 4riw D: [261572]
      Other proteins in same PDB: d4riwa_, d4riwc_
      automated match to d3ikaa_
      complexed with adp, anp, mg
  39. Domain(s) for 4rix:
    1. 2543588Domain d4rixb_: 4rix B: [261968]
      Other proteins in same PDB: d4rixa_, d4rixc_
      automated match to d3ikaa_
      complexed with adp, anp, mg; mutant
    2. 2543589Domain d4rixd_: 4rix D: [261969]
      Other proteins in same PDB: d4rixa_, d4rixc_
      automated match to d3ikaa_
      complexed with adp, anp, mg; mutant
  40. Domain(s) for 4riy:
    1. 2543585Domain d4riyb_: 4riy B: [261570]
      Other proteins in same PDB: d4riya_, d4riyc_
      automated match to d3ikaa_
      complexed with adp, anp, mg; mutant
    2. 2543586Domain d4riyd_: 4riy D: [261571]
      Other proteins in same PDB: d4riya_, d4riyc_
      automated match to d3ikaa_
      complexed with adp, anp, mg; mutant
  41. Domain(s) for 4rj4:
  42. Domain(s) for 4rj5:
  43. Domain(s) for 4rj6:
  44. Domain(s) for 4rj7:
  45. Domain(s) for 4rj8:
  46. Domain(s) for 4wkq:
  47. Domain(s) for 4wrg:
  48. Domain(s) for 4zau:
  49. Domain(s) for 4zse:
    1. 2543529Domain d4zsea_: 4zse A: [318634]
      automated match to d3ikaa_
      complexed with anp, edo, mg
    2. 2543530Domain d4zseb_: 4zse B: [318633]
      automated match to d3ikaa_
      complexed with anp, edo, mg
    3. 2543531Domain d4zsec_: 4zse C: [318666]
      automated match to d3ikaa_
      complexed with anp, edo, mg
    4. 2543532Domain d4zsed_: 4zse D: [318635]
      automated match to d3ikaa_
      complexed with anp, edo, mg
  50. Domain(s) for 5c8k:
  51. Domain(s) for 5c8m:
  52. Domain(s) for 5c8n:
  53. Domain(s) for 5cal:
  54. Domain(s) for 5can:
  55. Domain(s) for 5cao:
  56. Domain(s) for 5cap:
  57. Domain(s) for 5caq:
  58. Domain(s) for 5cas:
  59. Domain(s) for 5cau:
  60. Domain(s) for 5cav:
  61. Domain(s) for 5cnn:
    1. 2543525Domain d5cnna_: 5cnn A: [275382]
      automated match to d4li5a_
      complexed with anp, mg; mutant
    2. 2543526Domain d5cnnb_: 5cnn B: [275375]
      automated match to d4li5a_
      complexed with anp, mg; mutant
  62. Domain(s) for 5cno:
    1. 2543511Domain d5cnoa_: 5cno A: [275380]
      automated match to d4li5a_
      complexed with anp, mg; mutant
    2. 2543512Domain d5cnob_: 5cno B: [275378]
      automated match to d4li5a_
      complexed with anp, mg; mutant
    3. 2543513Domain d5cnox_: 5cno X: [275379]
      automated match to d4li5a_
      complexed with anp, mg; mutant
  63. Domain(s) for 5d41:
    1. 2543553Domain d5d41a_: 5d41 A: [318136]
      automated match to d3ikaa_
      complexed with 57n, anp, mg; mutant
    2. 2543554Domain d5d41b_: 5d41 B: [318089]
      automated match to d3ikaa_
      complexed with 57n, anp, mg; mutant
  64. Domain(s) for 5edp:
  65. Domain(s) for 5edq:
  66. Domain(s) for 5edr:
  67. Domain(s) for 5em5:
  68. Domain(s) for 5em6:
  69. Domain(s) for 5em7:
  70. Domain(s) for 5em8:
  71. Domain(s) for 5fed:
  72. Domain(s) for 5fee:
  73. Domain(s) for 5gmp:
  74. Domain(s) for 5gnk:
  75. Domain(s) for 5gty:
    1. 2543610Domain d5gtya_: 5gty A: [338500]
      automated match to d3ikaa_
      complexed with 816, edo
    2. 2543611Domain d5gtyb_: 5gty B: [338508]
      automated match to d3ikaa_
      complexed with 816, edo
    3. 2543612Domain d5gtyc_: 5gty C: [338505]
      automated match to d3ikaa_
      complexed with 816, edo
    4. 2543613Domain d5gtyd_: 5gty D: [338512]
      automated match to d3ikaa_
      complexed with 816, edo
    5. 2543614Domain d5gtye_: 5gty E: [338496]
      automated match to d3ikaa_
      complexed with 816, edo
    6. 2543615Domain d5gtyf_: 5gty F: [338520]
      automated match to d3ikaa_
      complexed with 816, edo
    7. 2543616Domain d5gtyg_: 5gty G: [338498]
      automated match to d3ikaa_
      complexed with 816, edo
    8. 2543617Domain d5gtyh_: 5gty H: [338506]
      automated match to d3ikaa_
      complexed with 816, edo
  76. Domain(s) for 5gtz:
  77. Domain(s) for 5hcx:
  78. Domain(s) for 5hcy:
  79. Domain(s) for 5hcz:
  80. Domain(s) for 5hg5:
  81. Domain(s) for 5hg8:
  82. Domain(s) for 5hib:
  83. Domain(s) for 5hic:
  84. Domain(s) for 5j9y:
  85. Domain(s) for 5j9z:
  86. Domain(s) for 5ugb:
  87. Domain(s) for 5x26:
  88. Domain(s) for 5x27:
  89. Domain(s) for 5x28:
  90. Domain(s) for 5x2a:
    1. 3048487Domain d5x2aa_: 5x2a A: [348549]
      automated match to d4zseb_
      complexed with 7xo, anp, cl, edo, mg
    2. 3048541Domain d5x2ab_: 5x2a B: [348603]
      automated match to d4zseb_
      complexed with 7xo, anp, cl, edo, mg
    3. 3048587Domain d5x2ac_: 5x2a C: [348649]
      automated match to d4zseb_
      complexed with 7xo, anp, cl, edo, mg
    4. 3048669Domain d5x2ad_: 5x2a D: [348731]
      automated match to d4zseb_
      complexed with 7xo, anp, cl, edo, mg
  91. Domain(s) for 5x2c:
    1. 3048325Domain d5x2ca_: 5x2c A: [348387]
      automated match to d4zseb_
      complexed with 7xr, cl, edo
    2. 3048628Domain d5x2cb_: 5x2c B: [348690]
      automated match to d4zseb_
      complexed with 7xr, cl, edo
  92. Domain(s) for 5x2f:
    1. 3048993Domain d5x2fa_: 5x2f A: [349055]
      automated match to d4zseb_
      complexed with 7xu
    2. 3049159Domain d5x2fb_: 5x2f B: [349221]
      automated match to d4zseb_
      complexed with 7xu
    3. 3049400Domain d5x2fc_: 5x2f C: [349462]
      automated match to d4zseb_
      complexed with 7xu
    4. 3049618Domain d5x2fd_: 5x2f D: [349680]
      automated match to d4zseb_
      complexed with 7xu
  93. Domain(s) for 5xdk:
  94. Domain(s) for 5xdl:
  95. Domain(s) for 5xgm:
  96. Domain(s) for 5xgn:
    1. 2543607Domain d5xgna_: 5xgn A: [340168]
      automated match to d3ikaa_
      complexed with 85x, cl
    2. 2543608Domain d5xgnb_: 5xgn B: [340175]
      automated match to d3ikaa_
      complexed with 85x, cl
  97. Domain(s) for 5y25:
  98. Domain(s) for 5yu9:
    1. 3048975Domain d5yu9a_: 5yu9 A: [349037]
      automated match to d4zseb_
      complexed with 1e8, cl
    2. 3049097Domain d5yu9c_: 5yu9 C: [349159]
      automated match to d4zseb_
      complexed with 1e8, cl
    3. 3049152Domain d5yu9b_: 5yu9 B: [349214]
      automated match to d4zseb_
      complexed with 1e8, cl
    4. 3049247Domain d5yu9d_: 5yu9 D: [349309]
      automated match to d4zseb_
      complexed with 1e8, cl
  99. Domain(s) for 5zto:
  100. Domain(s) for 6d8e:
  101. Domain(s) for 6duk:
    1. 3069693Domain d6dukf_: 6duk F: [369755]
      automated match to d4zseb_
      complexed with anp, jbj, mg
    2. 3069705Domain d6dukb_: 6duk B: [369767]
      automated match to d4zseb_
      complexed with anp, jbj, mg
    3. 3069781Domain d6dukd_: 6duk D: [369843]
      automated match to d4zseb_
      complexed with anp, jbj, mg
    4. 3069792Domain d6duka_: 6duk A: [369854]
      automated match to d4zseb_
      complexed with anp, jbj, mg
    5. 3069796Domain d6duke_: 6duk E: [369858]
      automated match to d4zseb_
      complexed with anp, jbj, mg
    6. 3069850Domain d6dukc_: 6duk C: [369912]
      automated match to d4zseb_
      complexed with anp, jbj, mg
  102. Domain(s) for 6s89:
  103. Domain(s) for 6s8a:

More info for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 EGF receptor tyrosine kinase, Erbb-1

Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 EGF receptor tyrosine kinase, Erbb-1: