Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2979693Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2981114Protein EGF receptor tyrosine kinase, Erbb-1 [82795] (1 species)
    PTK group; EGFR subfamily; membrane spanning protein tyrosine kinase
  7. 2981115Species Human (Homo sapiens) [TaxId:9606] [82796] (129 PDB entries)
    Uniprot P00533 702-1018

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1m14:
  2. Domain(s) for 1m17:
  3. Domain(s) for 1xkk:
  4. Domain(s) for 2eb2:
  5. Domain(s) for 2eb3:
  6. Domain(s) for 2gs2:
  7. Domain(s) for 2gs6:
  8. Domain(s) for 2gs7:
    1. 2981202Domain d2gs7a_: 2gs7 A: [164827]
      automated match to d1m14a_
      complexed with anp, iod, mg
    2. 2981203Domain d2gs7b_: 2gs7 B: [164828]
      automated match to d1m14a_
      complexed with anp, iod, mg
  9. Domain(s) for 2ity:
  10. Domain(s) for 2rfe:
  11. Domain(s) for 2rgp:
  12. Domain(s) for 3bel:
  13. Domain(s) for 3gt8:
    1. 2981249Domain d3gt8a_: 3gt8 A: [176980]
      automated match to d1m14a_
      complexed with anp, mg
    2. 2981250Domain d3gt8b_: 3gt8 B: [176981]
      automated match to d1m14a_
      complexed with anp, mg
    3. 2981251Domain d3gt8c_: 3gt8 C: [176982]
      automated match to d1m14a_
      complexed with anp, mg
    4. 2981252Domain d3gt8d_: 3gt8 D: [176983]
      automated match to d1m14a_
      complexed with anp, mg
  14. Domain(s) for 3ika:
    1. 2981253Domain d3ikaa_: 3ika A: [178367]
      automated match to d1m14a_
      complexed with 0un; mutant
    2. 2981254Domain d3ikab_: 3ika B: [178368]
      automated match to d1m14a_
      complexed with 0un; mutant
  15. Domain(s) for 3poz:
  16. Domain(s) for 3ug1:
  17. Domain(s) for 3ug2:
  18. Domain(s) for 3vjn:
  19. Domain(s) for 3vjo:
  20. Domain(s) for 3w2o:
  21. Domain(s) for 3w2p:
  22. Domain(s) for 3w2q:
  23. Domain(s) for 3w2r:
  24. Domain(s) for 3w2s:
  25. Domain(s) for 3w32:
  26. Domain(s) for 3w33:
  27. Domain(s) for 4hjo:
  28. Domain(s) for 4i22:
  29. Domain(s) for 4i23:
  30. Domain(s) for 4i24:
    1. 2981120Domain d4i24a_: 4i24 A: [193289]
      automated match to d1m14a_
      complexed with 1c9
    2. 2981121Domain d4i24b_: 4i24 B: [234764]
      automated match to d4i24a_
      complexed with 1c9
  31. Domain(s) for 4jq7:
  32. Domain(s) for 4jq8:
  33. Domain(s) for 4jr3:
  34. Domain(s) for 4jrv:
  35. Domain(s) for 4li5:
  36. Domain(s) for 4lqm:
  37. Domain(s) for 4r5s:
  38. Domain(s) for 4riw:
    1. 2981305Domain d4riwb_: 4riw B: [261970]
      Other proteins in same PDB: d4riwa_, d4riwc_
      automated match to d3ikaa_
      complexed with adp, anp, mg
    2. 2981306Domain d4riwd_: 4riw D: [261572]
      Other proteins in same PDB: d4riwa_, d4riwc_
      automated match to d3ikaa_
      complexed with adp, anp, mg
  39. Domain(s) for 4rix:
    1. 2981287Domain d4rixb_: 4rix B: [261968]
      Other proteins in same PDB: d4rixa_, d4rixc_
      automated match to d3ikaa_
      complexed with adp, anp, mg; mutant
    2. 2981288Domain d4rixd_: 4rix D: [261969]
      Other proteins in same PDB: d4rixa_, d4rixc_
      automated match to d3ikaa_
      complexed with adp, anp, mg; mutant
  40. Domain(s) for 4riy:
    1. 2981284Domain d4riyb_: 4riy B: [261570]
      Other proteins in same PDB: d4riya_, d4riyc_
      automated match to d3ikaa_
      complexed with adp, anp, mg; mutant
    2. 2981285Domain d4riyd_: 4riy D: [261571]
      Other proteins in same PDB: d4riya_, d4riyc_
      automated match to d3ikaa_
      complexed with adp, anp, mg; mutant
  41. Domain(s) for 4rj4:
  42. Domain(s) for 4rj5:
  43. Domain(s) for 4rj6:
  44. Domain(s) for 4rj7:
  45. Domain(s) for 4rj8:
  46. Domain(s) for 4wkq:
  47. Domain(s) for 4wrg:
  48. Domain(s) for 4zau:
  49. Domain(s) for 4zse:
    1. 2981162Domain d4zsea_: 4zse A: [318634]
      automated match to d3ikaa_
      complexed with anp, edo, mg
    2. 2981163Domain d4zseb_: 4zse B: [318633]
      automated match to d3ikaa_
      complexed with anp, edo, mg
    3. 2981164Domain d4zsec_: 4zse C: [318666]
      automated match to d3ikaa_
      complexed with anp, edo, mg
    4. 2981165Domain d4zsed_: 4zse D: [318635]
      automated match to d3ikaa_
      complexed with anp, edo, mg
  50. Domain(s) for 5c8k:
  51. Domain(s) for 5c8m:
  52. Domain(s) for 5c8n:
  53. Domain(s) for 5cal:
  54. Domain(s) for 5can:
  55. Domain(s) for 5cao:
  56. Domain(s) for 5cap:
  57. Domain(s) for 5caq:
  58. Domain(s) for 5cas:
  59. Domain(s) for 5cau:
  60. Domain(s) for 5cav:
  61. Domain(s) for 5cnn:
    1. 2981149Domain d5cnna_: 5cnn A: [275382]
      automated match to d4li5a_
      complexed with anp, mg; mutant
    2. 2981150Domain d5cnnb_: 5cnn B: [275375]
      automated match to d4li5a_
      complexed with anp, mg; mutant
  62. Domain(s) for 5cno:
    1. 2981123Domain d5cnoa_: 5cno A: [275380]
      automated match to d4li5a_
      complexed with anp, mg; mutant
    2. 2981124Domain d5cnob_: 5cno B: [275378]
      automated match to d4li5a_
      complexed with anp, mg; mutant
    3. 2981125Domain d5cnox_: 5cno X: [275379]
      automated match to d4li5a_
      complexed with anp, mg; mutant
  63. Domain(s) for 5d41:
    1. 2981231Domain d5d41a_: 5d41 A: [318136]
      automated match to d3ikaa_
      complexed with 57n, anp, mg; mutant
    2. 2981232Domain d5d41b_: 5d41 B: [318089]
      automated match to d3ikaa_
      complexed with 57n, anp, mg; mutant
  64. Domain(s) for 5edp:
  65. Domain(s) for 5edq:
  66. Domain(s) for 5edr:
  67. Domain(s) for 5em5:
  68. Domain(s) for 5em6:
  69. Domain(s) for 5em7:
  70. Domain(s) for 5em8:
  71. Domain(s) for 5fed:
  72. Domain(s) for 5fee:
  73. Domain(s) for 5gmp:
  74. Domain(s) for 5gnk:
  75. Domain(s) for 5gty:
    1. 2981320Domain d5gtya_: 5gty A: [338500]
      automated match to d3ikaa_
      complexed with 816, edo
    2. 2981321Domain d5gtyb_: 5gty B: [338508]
      automated match to d3ikaa_
      complexed with 816, edo
    3. 2981322Domain d5gtyc_: 5gty C: [338505]
      automated match to d3ikaa_
      complexed with 816, edo
    4. 2981323Domain d5gtyd_: 5gty D: [338512]
      automated match to d3ikaa_
      complexed with 816, edo
    5. 2981324Domain d5gtye_: 5gty E: [338496]
      automated match to d3ikaa_
      complexed with 816, edo
    6. 2981325Domain d5gtyf_: 5gty F: [338520]
      automated match to d3ikaa_
      complexed with 816, edo
    7. 2981326Domain d5gtyg_: 5gty G: [338498]
      automated match to d3ikaa_
      complexed with 816, edo
    8. 2981327Domain d5gtyh_: 5gty H: [338506]
      automated match to d3ikaa_
      complexed with 816, edo
  76. Domain(s) for 5gtz:
  77. Domain(s) for 5hcx:
  78. Domain(s) for 5hcy:
  79. Domain(s) for 5hcz:
  80. Domain(s) for 5hg5:
  81. Domain(s) for 5hg8:
  82. Domain(s) for 5hib:
  83. Domain(s) for 5hic:
  84. Domain(s) for 5j9y:
  85. Domain(s) for 5j9z:
  86. Domain(s) for 5ugb:
  87. Domain(s) for 5x26:
  88. Domain(s) for 5x27:
  89. Domain(s) for 5x28:
  90. Domain(s) for 5x2a:
    1. 2981145Domain d5x2aa_: 5x2a A: [348549]
      automated match to d4zseb_
      complexed with 7xo, anp, cl, edo, mg
    2. 2981146Domain d5x2ab_: 5x2a B: [348603]
      automated match to d4zseb_
      complexed with 7xo, anp, cl, edo, mg
    3. 2981147Domain d5x2ac_: 5x2a C: [348649]
      automated match to d4zseb_
      complexed with 7xo, anp, cl, edo, mg
    4. 2981148Domain d5x2ad_: 5x2a D: [348731]
      automated match to d4zseb_
      complexed with 7xo, anp, cl, edo, mg
  91. Domain(s) for 5x2c:
    1. 2981173Domain d5x2ca_: 5x2c A: [348387]
      automated match to d4zseb_
      complexed with 7xr, cl, edo
    2. 2981174Domain d5x2cb_: 5x2c B: [348690]
      automated match to d4zseb_
      complexed with 7xr, cl, edo
  92. Domain(s) for 5x2f:
    1. 2981215Domain d5x2fa_: 5x2f A: [349055]
      automated match to d4zseb_
      complexed with 7xu
    2. 2981216Domain d5x2fb_: 5x2f B: [349221]
      automated match to d4zseb_
      complexed with 7xu
    3. 2981217Domain d5x2fc_: 5x2f C: [349462]
      automated match to d4zseb_
      complexed with 7xu
    4. 2981218Domain d5x2fd_: 5x2f D: [349680]
      automated match to d4zseb_
      complexed with 7xu
  93. Domain(s) for 5xdk:
  94. Domain(s) for 5xdl:
  95. Domain(s) for 5xgm:
  96. Domain(s) for 5xgn:
    1. 2981317Domain d5xgna_: 5xgn A: [340168]
      automated match to d3ikaa_
      complexed with 85x, cl
    2. 2981318Domain d5xgnb_: 5xgn B: [340175]
      automated match to d3ikaa_
      complexed with 85x, cl
  97. Domain(s) for 5y25:
  98. Domain(s) for 5yu9:
    1. 2981157Domain d5yu9a_: 5yu9 A: [349037]
      automated match to d4zseb_
      complexed with 1e8, cl
    2. 2981158Domain d5yu9b_: 5yu9 B: [349214]
      automated match to d4zseb_
      complexed with 1e8, cl
    3. 2981159Domain d5yu9c_: 5yu9 C: [349159]
      automated match to d4zseb_
      complexed with 1e8, cl
    4. 2981160Domain d5yu9d_: 5yu9 D: [349309]
      automated match to d4zseb_
      complexed with 1e8, cl
  99. Domain(s) for 5zto:
  100. Domain(s) for 6d8e:
  101. Domain(s) for 6duk:
    1. 2981219Domain d6duka_: 6duk A: [369854]
      automated match to d4zseb_
      complexed with anp, jbj, mg
    2. 2981220Domain d6dukb_: 6duk B: [369767]
      automated match to d4zseb_
      complexed with anp, jbj, mg
    3. 2981221Domain d6dukc_: 6duk C: [369912]
      automated match to d4zseb_
      complexed with anp, jbj, mg
    4. 2981222Domain d6dukd_: 6duk D: [369843]
      automated match to d4zseb_
      complexed with anp, jbj, mg
    5. 2981223Domain d6duke_: 6duk E: [369858]
      automated match to d4zseb_
      complexed with anp, jbj, mg
    6. 2981224Domain d6dukf_: 6duk F: [369755]
      automated match to d4zseb_
      complexed with anp, jbj, mg
  102. Domain(s) for 6jrj:
  103. Domain(s) for 6jrk:
  104. Domain(s) for 6jrx:
  105. Domain(s) for 6jwl:
  106. Domain(s) for 6jx4:
  107. Domain(s) for 6jz0:
  108. Domain(s) for 6lub:
  109. Domain(s) for 6lud:
  110. Domain(s) for 6p1d:
    1. 2981239Domain d6p1da_: 6p1d A: [378282]
      automated match to d4zseb_
      complexed with anp, mg, nq1; mutant
    2. 2981240Domain d6p1db_: 6p1d B: [378286]
      automated match to d4zseb_
      complexed with anp, mg, nq1; mutant
    3. 2981241Domain d6p1dc_: 6p1d C: [378284]
      automated match to d4zseb_
      complexed with anp, mg, nq1; mutant
    4. 2981242Domain d6p1dd_: 6p1d D: [378285]
      automated match to d4zseb_
      complexed with anp, mg, nq1; mutant
  111. Domain(s) for 6p1l:
    1. 2981289Domain d6p1la_: 6p1l A: [378291]
      automated match to d4zseb_
      complexed with 9ll, anp, mg
    2. 2981290Domain d6p1lb_: 6p1l B: [378299]
      automated match to d4zseb_
      complexed with 9ll, anp, mg
    3. 2981291Domain d6p1lc_: 6p1l C: [378281]
      automated match to d4zseb_
      complexed with 9ll, anp, mg
    4. 2981292Domain d6p1ld_: 6p1l D: [378283]
      automated match to d4zseb_
      complexed with 9ll, anp, mg
  112. Domain(s) for 6p8q:
    1. 2981152Domain d6p8qa_: 6p8q A: [378292]
      automated match to d4zseb_
      complexed with amp, anp, edo, mg, o57
    2. 2981153Domain d6p8qb_: 6p8q B: [378305]
      automated match to d4zseb_
      complexed with amp, anp, edo, mg, o57
    3. 2981154Domain d6p8qc_: 6p8q C: [378313]
      automated match to d4zseb_
      complexed with amp, anp, edo, mg, o57
    4. 2981155Domain d6p8qd_: 6p8q D: [378298]
      automated match to d4zseb_
      complexed with amp, anp, edo, mg, o57
  113. Domain(s) for 6s89:
  114. Domain(s) for 6s8a:
  115. Domain(s) for 6s9c:
  116. Domain(s) for 6s9d:
  117. Domain(s) for 6v5n:
    1. 2981255Domain d6v5na_: 6v5n A: [384536]
      automated match to d4zseb_
      complexed with cl, qp7
    2. 2981256Domain d6v5nb_: 6v5n B: [384565]
      automated match to d4zseb_
      complexed with cl, qp7
    3. 2981257Domain d6v5nc_: 6v5n C: [384564]
      automated match to d4zseb_
      complexed with cl, qp7
    4. 2981258Domain d6v5nd_: 6v5n D: [384552]
      automated match to d4zseb_
      complexed with cl, qp7
  118. Domain(s) for 6v5p:
    1. 2981233Domain d6v5pa_: 6v5p A: [384574]
      automated match to d4zseb_
      complexed with cl, qp4
    2. 2981234Domain d6v5pb_: 6v5p B: [384601]
      automated match to d4zseb_
      complexed with cl, qp4
    3. 2981235Domain d6v5pc_: 6v5p C: [384609]
      automated match to d4zseb_
      complexed with cl, qp4
    4. 2981236Domain d6v5pd_: 6v5p D: [384594]
      automated match to d4zseb_
      complexed with cl, qp4
  119. Domain(s) for 6v66:
    1. 2981138Domain d6v66a_: 6v66 A: [384434]
      automated match to d4zseb_
      complexed with cl, edo, qp1
    2. 2981139Domain d6v66b_: 6v66 B: [384429]
      automated match to d4zseb_
      complexed with cl, edo, qp1
    3. 2981140Domain d6v66c_: 6v66 C: [384499]
      automated match to d4zseb_
      complexed with cl, edo, qp1
    4. 2981141Domain d6v66d_: 6v66 D: [384591]
      automated match to d4zseb_
      complexed with cl, edo, qp1
  120. Domain(s) for 6v6k:
    1. 2981207Domain d6v6ka_: 6v6k A: [384533]
      automated match to d4zseb_
      complexed with cl, qqj
    2. 2981208Domain d6v6kb_: 6v6k B: [384453]
      automated match to d4zseb_
      complexed with cl, qqj
    3. 2981209Domain d6v6kc_: 6v6k C: [384580]
      automated match to d4zseb_
      complexed with cl, qqj
    4. 2981210Domain d6v6kd_: 6v6k D: [384558]
      automated match to d4zseb_
      complexed with cl, qqj
    5. 2981211Domain d6v6ke_: 6v6k E: [384508]
      automated match to d4zseb_
      complexed with cl, qqj
    6. 2981212Domain d6v6kf_: 6v6k F: [384600]
      automated match to d4zseb_
      complexed with cl, qqj
    7. 2981213Domain d6v6kg_: 6v6k G: [384586]
      automated match to d4zseb_
      complexed with cl, qqj
    8. 2981214Domain d6v6kh_: 6v6k H: [384610]
      automated match to d4zseb_
      complexed with cl, qqj
  121. Domain(s) for 6v6o:
    1. 2981175Domain d6v6oa_: 6v6o A: [384467]
      automated match to d4zseb_
      complexed with cl, qqm
    2. 2981176Domain d6v6ob_: 6v6o B: [384581]
      automated match to d4zseb_
      complexed with cl, qqm
    3. 2981177Domain d6v6oc_: 6v6o C: [384435]
      automated match to d4zseb_
      complexed with cl, qqm
    4. 2981178Domain d6v6od_: 6v6o D: [384613]
      automated match to d4zseb_
      complexed with cl, qqm
    5. 2981179Domain d6v6oe_: 6v6o E: [384437]
      automated match to d4zseb_
      complexed with cl, qqm
    6. 2981180Domain d6v6of_: 6v6o F: [384474]
      automated match to d4zseb_
      complexed with cl, qqm
    7. 2981181Domain d6v6og_: 6v6o G: [384428]
      automated match to d4zseb_
      complexed with cl, qqm
    8. 2981182Domain d6v6oh_: 6v6o H: [384492]
      automated match to d4zseb_
      complexed with cl, qqm
  122. Domain(s) for 6vh4:
  123. Domain(s) for 6vhn:
  124. Domain(s) for 6wa2:
    1. 2981184Domain d6wa2a_: 6wa2 A: [402810]
      automated match to d4zseb_
      complexed with cl, tov
    2. 2981185Domain d6wa2b_: 6wa2 B: [402712]
      automated match to d4zseb_
      complexed with cl, tov
    3. 2981186Domain d6wa2c_: 6wa2 C: [402687]
      automated match to d4zseb_
      complexed with cl, tov
    4. 2981187Domain d6wa2d_: 6wa2 D: [402708]
      automated match to d4zseb_
      complexed with cl, tov
  125. Domain(s) for 6wak:
    1. 2981190Domain d6waka_: 6wak A: [402651]
      automated match to d4zseb_
      complexed with anp, mg, tqa
    2. 2981191Domain d6wakb_: 6wak B: [402709]
      automated match to d4zseb_
      complexed with anp, mg, tqa
    3. 2981192Domain d6wakc_: 6wak C: [402692]
      automated match to d4zseb_
      complexed with anp, mg, tqa
    4. 2981193Domain d6wakd_: 6wak D: [402676]
      automated match to d4zseb_
      complexed with anp, mg, tqa
  126. Domain(s) for 6wxn:
    1. 2981126Domain d6wxna_: 6wxn A: [407310]
      automated match to d4zseb_
      complexed with anp, cl, mg, uej
    2. 2981127Domain d6wxnb_: 6wxn B: [407330]
      automated match to d4zseb_
      complexed with anp, cl, mg, uej
    3. 2981128Domain d6wxnc_: 6wxn C: [407274]
      automated match to d4zseb_
      complexed with anp, cl, mg, uej
    4. 2981129Domain d6wxnd_: 6wxn D: [407261]
      automated match to d4zseb_
      complexed with anp, cl, mg, uej
  127. Domain(s) for 6xl4:
    1. 2981133Domain d6xl4a_: 6xl4 A: [407354]
      automated match to d4zseb_
      complexed with anp, mg, nq1, q6k
    2. 2981134Domain d6xl4b_: 6xl4 B: [407307]
      automated match to d4zseb_
      complexed with anp, mg, nq1, q6k
    3. 2981135Domain d6xl4c_: 6xl4 C: [407412]
      automated match to d4zseb_
      complexed with anp, mg, nq1, q6k
    4. 2981136Domain d6xl4d_: 6xl4 D: [407347]
      automated match to d4zseb_
      complexed with anp, mg, nq1, q6k
  128. Domain(s) for 7aei:
  129. Domain(s) for 7aem:

More info for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 EGF receptor tyrosine kinase, Erbb-1

Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 EGF receptor tyrosine kinase, Erbb-1: