SCOPe 2.08: Domain d1e4ea2: 1e4e A:132-342

Lineage for d1e4ea2 (1e4e A:132-342)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.142: ATP-grasp [56058] (2 superfamilies)
   Consists of two subdomains with different alpha+beta folds
   shares functional and structural similarities with the PIPK and protein kinase superfamilies

4. Superfamily d.142.1: Glutathione synthetase ATP-binding domain-like [56059] (11 families)

5. Family d.142.1.1: ATP-binding domain of peptide synthetases [56060] (4 proteins)

6. Protein D-alanine:D-lactate ligase VanA, C-domain [56065] (2 species)

7. Species Enterococcus faecium [TaxId:1352] [64402] (1 PDB entry)

8. Domain d1e4ea2: 1e4e A:132-342 [59222]
   Other proteins in same PDB: d1e4ea1, d1e4eb1
   complexed with adp, gol, mg, phy, so4

Details for d1e4ea2

PDB Entry: 1e4e, 2.5 Å

PDB Description: d-alanyl-d-lacate ligase

PDB Compounds: (A:) vancomycin/teicoplanin a-type resistance protein vana

SCOPe Domain Sequences for d1e4ea2:

Sequence; same for both SEQRES and ATOM records:

>d1e4ea2 d.142.1.1 (A:132-342) D-alanine:D-lactate ligase VanA, C-domain {Enterococcus faecium [TaxId: 1352]}
dksltyivaknagiatpafwvinkddrpvaatftypvfvkparsgssfgvkkvnsadeld
yaiesarqydskilieqavsgcevgcavlgnsaalvvgevdqirlqygifrihqevepek
gsenavitvpadlsaeergriqetvkkiyktlgcrglarvdmflqdngrivlnevntlpg
ftsysryprmmaaagislpelidrlivlalk

Timeline for d1e4ea2:

• d1e4ea2 first appeared in SCOP 1.57
  
• d1e4ea2 appears in SCOPe 2.07