Lineage for Family d.32.1.3: Extradiol dioxygenases

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2166686Fold d.32: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54592] (1 superfamily)
    beta-alpha-beta(3); 2 layers: alpha/beta
  4. 2166687Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54593] (11 families) (S)
  5. 2166848Family d.32.1.3: Extradiol dioxygenases [54602] (5 protein domains)
    duplication: consists of 2 similar domains with 2 repeats in each
    Similar to the Methylmalonyl-CoA epimerase dimer

Protein Domains:

  1. 21668492,3-Dihydroxybiphenyl dioxygenase (DHBD, BPHC enzyme) [54603] (2 species)
    1. 2166850Species Burkholderia cepacia, formerly Pseudomonas cepacia [TaxId:292] [54605] (6 PDB entries)
    2. 2166863Species Pseudomonas sp. [TaxId:306] [54604] (11 PDB entries)
  2. 21668864-hydroxyphenylpyruvate dioxygenase, HppD [54608] (6 species)
    1. 2166887Species Human (Homo sapiens) [TaxId:9606] [110878] (1 PDB entry)
    2. 2166890Species Maize (Zea mays) [TaxId:4577] [110879] (1 PDB entry)
      Uniprot O48604 29-423 # 85% sequence identity
    3. 2166899Species Norway rat (Rattus norvegicus) [TaxId:10116] [256396] (1 PDB entry)
      Uniprot P32755
    4. 2166904Species Pseudomonas fluorescens [TaxId:294] [54609] (1 PDB entry)
    5. 2166913Species Streptomyces avermitilis [TaxId:33903] [110876] (1 PDB entry)
      Uniprot Q53586
    6. 2166918Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [110877] (5 PDB entries)
      Uniprot P93836 33-428 ! Uniprot P93836 63-459
  3. 2166929Catechol 2,3-dioxygenase (metapyrocatechase) [54606] (1 species)
  4. 2166939Homoprotocatechuate 2,3-dioxygenase [89886] (2 species)
    1. 2166940Species Arthrobacter globiformis [TaxId:1665] [89887] (3 PDB entries)
    2. 2166953Species Brevibacterium fuscum [TaxId:47914] [89888] (17 PDB entries)
  5. 2167074automated matches [276310] (3 species)
    not a true protein
    1. 2167075Species Human (Homo sapiens) [TaxId:9606] [279455] (1 PDB entry)
    2. 2167078Species Pseudomonas sp. [311137] (1 PDB entry)
    3. 2167081Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [276311] (1 PDB entry)

More info for Family d.32.1.3: Extradiol dioxygenases

Timeline for Family d.32.1.3: Extradiol dioxygenases: