Lineage for Family d.32.1.3: Extradiol dioxygenases

  1. Root: SCOPe 2.07
  2. 2530962Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2549433Fold d.32: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54592] (1 superfamily)
    beta-alpha-beta(3); 2 layers: alpha/beta
  4. 2549434Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54593] (11 families) (S)
  5. 2549597Family d.32.1.3: Extradiol dioxygenases [54602] (5 proteins)
    duplication: consists of 2 similar domains with 2 repeats in each
    Similar to the Methylmalonyl-CoA epimerase dimer

Proteins:

  1. 25495982,3-Dihydroxybiphenyl dioxygenase (DHBD, BPHC enzyme) [54603] (2 species)
    1. 2549599Species Burkholderia cepacia, formerly Pseudomonas cepacia [TaxId:292] [54605] (6 PDB entries)
    2. 2549612Species Pseudomonas sp. [TaxId:306] [54604] (11 PDB entries)
  2. 25496354-hydroxyphenylpyruvate dioxygenase, HppD [54608] (6 species)
    1. 2549636Species Human (Homo sapiens) [TaxId:9606] [110878] (1 PDB entry)
    2. 2549639Species Maize (Zea mays) [TaxId:4577] [110879] (1 PDB entry)
      Uniprot O48604 29-423 # 85% sequence identity
    3. 2549648Species Norway rat (Rattus norvegicus) [TaxId:10116] [256396] (1 PDB entry)
      Uniprot P32755
    4. 2549653Species Pseudomonas fluorescens [TaxId:294] [54609] (1 PDB entry)
    5. 2549662Species Streptomyces avermitilis [TaxId:33903] [110876] (1 PDB entry)
      Uniprot Q53586
    6. 2549667Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [110877] (15 PDB entries)
      Uniprot P93836 33-428 ! Uniprot P93836 63-459
  3. 2549722Catechol 2,3-dioxygenase (metapyrocatechase) [54606] (1 species)
  4. 2549732Homoprotocatechuate 2,3-dioxygenase [89886] (2 species)
    1. 2549733Species Arthrobacter globiformis [TaxId:1665] [89887] (3 PDB entries)
    2. 2549746Species Brevibacterium fuscum [TaxId:47914] [89888] (17 PDB entries)
  5. 2549875automated matches [276310] (3 species)
    not a true protein
    1. 2549876Species Human (Homo sapiens) [TaxId:9606] [279455] (1 PDB entry)
    2. 2549879Species Pseudomonas sp. [311137] (1 PDB entry)
    3. 2549882Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [276311] (1 PDB entry)

More info for Family d.32.1.3: Extradiol dioxygenases

Timeline for Family d.32.1.3: Extradiol dioxygenases: