SCOPe 2.02: Species: Mycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]

Lineage for Species: Mycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]

Root: SCOPe 2.02
Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
also known as short-chain dehydrogenases and SDR family
parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

Protein Enoyl-ACP reductase [51791] (11 species)
Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] [51793] (39 PDB entries)

PDB entries in Species: Mycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]:

Domain(s) for 1bvr:
1. Domain d1bvra_: 1bvr A: [29913]
  complexed with nad, tht
2. Domain d1bvrb_: 1bvr B: [29914]
  complexed with nad, tht
3. Domain d1bvrc_: 1bvr C: [29915]
  complexed with nad, tht
4. Domain d1bvrd_: 1bvr D: [29916]
  complexed with nad, tht
5. Domain d1bvre_: 1bvr E: [29917]
  complexed with nad, tht
6. Domain d1bvrf_: 1bvr F: [29918]
  complexed with nad, tht
Domain(s) for 1eny:
- Domain d1enya_: 1eny A: [29910]
  complexed with nad
Domain(s) for 1enz:
- Domain d1enza_: 1enz A: [29912]
  complexed with nad
Domain(s) for 1p44:
1. Domain d1p44a_: 1p44 A: [94076]
  complexed with geq, nad
2. Domain d1p44b_: 1p44 B: [94077]
  complexed with geq, nad
3. Domain d1p44c_: 1p44 C: [94078]
  complexed with geq, nad
4. Domain d1p44d_: 1p44 D: [94079]
  complexed with geq, nad
5. Domain d1p44e_: 1p44 E: [94080]
  complexed with geq, nad
6. Domain d1p44f_: 1p44 F: [94081]
  complexed with geq, nad
Domain(s) for 1p45:
1. Domain d1p45a_: 1p45 A: [94082]
  complexed with nad, tcl
2. Domain d1p45b_: 1p45 B: [94083]
  complexed with nad, tcl
Domain(s) for 1zid:
- Domain d1zida_: 1zid A: [29911]
  complexed with zid
Domain(s) for 2aq8:
- Domain d2aq8a_: 2aq8 A: [127166]
  automated match to d1bvra_
  complexed with lys, nad
Domain(s) for 2aqh:
- Domain d2aqha_: 2aqh A: [162857]
  automated match to d1bvra_
  complexed with nad; mutant
Domain(s) for 2aqi:
- Domain d2aqia_: 2aqi A: [162858]
  automated match to d1bvra_
  complexed with nad; mutant
Domain(s) for 2aqk:
- Domain d2aqka_: 2aqk A: [127181]
  automated match to d1bvra_
  complexed with nad; mutant
Domain(s) for 2b35:
1. Domain d2b35a_: 2b35 A: [127767]
  automated match to d1bvra_
  complexed with nad, tcl
2. Domain d2b35b_: 2b35 B: [127768]
  automated match to d1bvra_
  complexed with nad, tcl
3. Domain d2b35c_: 2b35 C: [127769]
  automated match to d1bvra_
  complexed with nad, tcl
4. Domain d2b35d_: 2b35 D: [127770]
  automated match to d1bvra_
  complexed with nad, tcl
5. Domain d2b35e_: 2b35 E: [127771]
  automated match to d1bvra_
  complexed with nad, tcl
6. Domain d2b35f_: 2b35 F: [127772]
  automated match to d1bvra_
  complexed with nad, tcl
Domain(s) for 2b36:
1. Domain d2b36a_: 2b36 A: [127773]
  automated match to d1bvra_
  complexed with 5pp, nad
2. Domain d2b36b_: 2b36 B: [127774]
  automated match to d1bvra_
  complexed with 5pp, nad
3. Domain d2b36c_: 2b36 C: [127775]
  automated match to d1bvra_
  complexed with 5pp, nad
4. Domain d2b36d_: 2b36 D: [127776]
  automated match to d1bvra_
  complexed with 5pp, nad
5. Domain d2b36e_: 2b36 E: [127777]
  automated match to d1bvra_
  complexed with 5pp, nad
6. Domain d2b36f_: 2b36 F: [127778]
  automated match to d1bvra_
  complexed with 5pp, nad
Domain(s) for 2b37:
1. Domain d2b37a_: 2b37 A: [127779]
  automated match to d1bvra_
  complexed with 8ps, nad
2. Domain d2b37b_: 2b37 B: [127780]
  automated match to d1bvra_
  complexed with 8ps, nad
3. Domain d2b37c_: 2b37 C: [127781]
  automated match to d1bvra_
  complexed with 8ps, nad
4. Domain d2b37d_: 2b37 D: [127782]
  automated match to d1bvra_
  complexed with 8ps, nad
5. Domain d2b37e_: 2b37 E: [127783]
  automated match to d1bvra_
  complexed with 8ps, nad
6. Domain d2b37f_: 2b37 F: [127784]
  automated match to d1bvra_
  complexed with 8ps, nad
Domain(s) for 2h7i:
- Domain d2h7ia_: 2h7i A: [136215]
  automated match to d1bvra_
  complexed with 566, nad
Domain(s) for 2h7l:
- Domain d2h7la_: 2h7l A: [136218]
  automated match to d1bvra_
  complexed with 665, nad
Domain(s) for 2h7m:
- Domain d2h7ma_: 2h7m A: [136219]
  automated match to d1bvra_
  complexed with 641, nad
Domain(s) for 2h7n:
- Domain d2h7na_: 2h7n A: [136220]
  automated match to d1bvra_
  complexed with 744, nad
Domain(s) for 2h7p:
- Domain d2h7pa_: 2h7p A: [136221]
  automated match to d1bvra_
  complexed with 468, nad
Domain(s) for 2h9i:
- Domain d2h9ia_: 2h9i A: [136265]
  automated match to d1eny__
  complexed with ead
Domain(s) for 2idz:
- Domain d2idza_: 2idz A: [147641]
  automated match to d1bvra_
  complexed with zid
Domain(s) for 2ie0:
- Domain d2ie0a_: 2ie0 A: [165521]
  automated match to d1bvra_
  complexed with zid; mutant
Domain(s) for 2ieb:
- Domain d2ieba_: 2ieb A: [147642]
  automated match to d1bvra_
  complexed with zid; mutant
Domain(s) for 2ied:
1. Domain d2ieda_: 2ied A: [147643]
  automated match to d1bvra_
  mutant
2. Domain d2iedb_: 2ied B: [147644]
  automated match to d1bvra_
  mutant
3. Domain d2iedc_: 2ied C: [147645]
  automated match to d1bvra_
  mutant
4. Domain d2iedd_: 2ied D: [147646]
  automated match to d1bvra_
  mutant
Domain(s) for 2nsd:
1. Domain d2nsda_: 2nsd A: [148384]
  automated match to d1bvra_
  complexed with 4pi, nad
2. Domain d2nsdb_: 2nsd B: [148385]
  automated match to d1bvra_
  complexed with 4pi, nad
Domain(s) for 2ntj:
1. Domain d2ntja_: 2ntj A: [138581]
  automated match to d1eny__
  complexed with p1h
2. Domain d2ntjb_: 2ntj B: [138582]
  automated match to d1eny__
  complexed with p1h
Domain(s) for 2nv6:
- Domain d2nv6a_: 2nv6 A: [138627]
  automated match to d1eny__
  complexed with zid
Domain(s) for 2pr2:
- Domain d2pr2a_: 2pr2 A: [149796]
  automated match to d1bvra_
  complexed with dg1
Domain(s) for 2x22:
1. Domain d2x22a_: 2x22 A: [169811]
  automated match to d1bvra_
  complexed with dms, nad, tcu
2. Domain d2x22b_: 2x22 B: [169812]
  automated match to d1bvra_
  complexed with dms, nad, tcu
Domain(s) for 2x23:
1. Domain d2x23a_: 2x23 A: [169813]
  automated match to d1bvra_
  complexed with dms, nad, tcu
2. Domain d2x23b_: 2x23 B: [169814]
  automated match to d1bvra_
  complexed with dms, nad, tcu
3. Domain d2x23e_: 2x23 E: [169815]
  automated match to d1bvra_
  complexed with dms, nad, tcu
4. Domain d2x23g_: 2x23 G: [169816]
  automated match to d1bvra_
  complexed with dms, nad, tcu
Domain(s) for 3fne:
1. Domain d3fnea_: 3fne A: [175911]
  automated match to d1bvra_
  complexed with 8pc, nad
2. Domain d3fneb_: 3fne B: [175912]
  automated match to d1bvra_
  complexed with 8pc, nad
3. Domain d3fnec_: 3fne C: [175913]
  automated match to d1bvra_
  complexed with 8pc, nad
4. Domain d3fned_: 3fne D: [175914]
  automated match to d1bvra_
  complexed with 8pc, nad
Domain(s) for 3fnf:
1. Domain d3fnfa_: 3fnf A: [175915]
  automated match to d1bvra_
  complexed with jpm, nad
2. Domain d3fnfb_: 3fnf B: [175916]
  automated match to d1bvra_
  complexed with jpm, nad
3. Domain d3fnfc_: 3fnf C: [175917]
  automated match to d1bvra_
  complexed with jpm, nad
4. Domain d3fnfd_: 3fnf D: [175918]
  automated match to d1bvra_
  complexed with jpm, nad
Domain(s) for 3fng:
- Domain d3fnga_: 3fng A: [175919]
  automated match to d1bvra_
  complexed with jpl, nad
Domain(s) for 3fnh:
- Domain d3fnha_: 3fnh A: [175920]
  automated match to d1bvra_
  complexed with jpj, nad
Domain(s) for 3oew:
- Domain d3oewa_: 3oew A: [182969]
  automated match to d1bvra_
  complexed with mpd, nad
Domain(s) for 3oey:
- Domain d3oeya_: 3oey A: [182974]
  automated match to d1bvra_
  complexed with mpd, nad
Domain(s) for 3of2:
- Domain d3of2a_: 3of2 A: [182975]
  automated match to d1bvra_
  complexed with mpd, nad
Domain(s) for 4dqu:
- Domain d4dqua_: 4dqu A: [193770]
  automated match to d2h7ma_
  complexed with nad; mutant
Domain(s) for 4dre:
- Domain d4drea_: 4dre A: [194609]
  automated match to d2h7ma_
  complexed with nad
Domain(s) for 4dti:
- Domain d4dtia_: 4dti A: [194608]
  automated match to d2ieda_
  complexed with nad; mutant

More info for Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] from c.2.1.2 Enoyl-ACP reductase

Timeline for Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] from c.2.1.2 Enoyl-ACP reductase:

Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] from c.2.1.2 Enoyl-ACP reductase first appeared (with stable ids) in SCOP 1.55
Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] from c.2.1.2 Enoyl-ACP reductase appears in SCOPe 2.01
Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] from c.2.1.2 Enoyl-ACP reductase appears in SCOPe 2.03
Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] from c.2.1.2 Enoyl-ACP reductase appears in the current release, SCOPe 2.08