| Class a: All alpha proteins [46456] (284 folds) |
| Fold a.26: 4-helical cytokines [47265] (1 superfamily) core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections |
Superfamily a.26.1: 4-helical cytokines [47266] (3 families) ![]() there are two different topoisomers of this fold with different entanglements of the two crossover connections |
| Family a.26.1.1: Long-chain cytokines [47267] (9 proteins) |
| Protein Leukemia inhibitory factor (LIF) [47274] (2 species) |
| Human (Homo sapiens) [TaxId:9606] [63529] (3 PDB entries) |
| Domain d1emra_: 1emr A: [59456] |
| Domain d1pvhb_: 1pvh B: [95167] Other proteins in same PDB: d1pvha1, d1pvha2, d1pvhc1, d1pvhc2 |
| Domain d1pvhd_: 1pvh D: [95170] Other proteins in same PDB: d1pvha1, d1pvha2, d1pvhc1, d1pvhc2 complexed with iod |
| Domain d2q7nb1: 2q7n B:12-180 [150094] automatically matched to d1pvhb_ complexed with fuc, man, nag |
| Domain d2q7nd1: 2q7n D:12-180 [150095] automatically matched to d1pvhb_ complexed with fuc, man, nag |
| Mouse (Mus musculus) [TaxId:10090] [47275] (2 PDB entries) |
| Domain d1a7ma_: 1a7m A: [16830] mouse-human chimera, residues 48-81 are from human sequence mutant |
| Domain d1lkia_: 1lki A: [16829] |
Timeline for Protein Leukemia inhibitory factor (LIF) from a.26.1.1: Long-chain cytokines: