Lineage for Protein: Leukemia inhibitory factor (LIF)

  1. Root: SCOP 1.73
  2. 631650Class a: All alpha proteins [46456] (258 folds)
  3. 639436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 639437Superfamily a.26.1: 4-helical cytokines [47266] (3 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 639438Family a.26.1.1: Long-chain cytokines [47267] (9 proteins)
  6. 639490Protein Leukemia inhibitory factor (LIF) [47274] (2 species)

Species:

  1. 639491Human (Homo sapiens) [TaxId:9606] [63529] (2 PDB entries)
    1. Domain for 1emr:
    2. Domains for 1pvh:
      1. 639492Domain d1pvhb_: 1pvh B: [95167]
        Other proteins in same PDB: d1pvha1, d1pvha2, d1pvhc1, d1pvhc2
      2. 639493Domain d1pvhd_: 1pvh D: [95170]
        Other proteins in same PDB: d1pvha1, d1pvha2, d1pvhc1, d1pvhc2
        complexed with iod
  2. 639495Mouse (Mus musculus) [TaxId:10090] [47275] (2 PDB entries)
    1. Domain for 1a7m:
      • 639497Domain d1a7ma_: 1a7m A: [16830]
        mouse-human chimera, residues 48-81 are from human sequence
        mutant
    2. Domain for 1lki:

More info for Protein Leukemia inhibitory factor (LIF) from a.26.1.1: Long-chain cytokines

Timeline for Protein Leukemia inhibitory factor (LIF) from a.26.1.1: Long-chain cytokines: