SCOP 1.75: Domain d1emra_: 1emr A:

Lineage for d1emra_ (1emr A:)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.26: 4-helical cytokines [47265] (1 superfamily)
   core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections

4. Superfamily a.26.1: 4-helical cytokines [47266] (3 families)
   there are two different topoisomers of this fold with different entanglements of the two crossover connections

5. Family a.26.1.1: Long-chain cytokines [47267] (9 proteins)

6. Protein Leukemia inhibitory factor (LIF) [47274] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63529] (3 PDB entries)

8. Domain d1emra_: 1emr A: [59456]

Details for d1emra_

PDB Entry: 1emr, 3.5 Å

PDB Description: crystal structure of human leukemia inhibitory factor (lif)

PDB Compounds: (A:) leukemia inhibitory factor

SCOP Domain Sequences for d1emra_:

Sequence; same for both SEQRES and ATOM records:

>d1emra_ a.26.1.1 (A:) Leukemia inhibitory factor (LIF) {Human (Homo sapiens) [TaxId: 9606]}
lmnqirsqlaqlngsanalfilyytaqgepfpnnleklcgpnvtdfppfhangtekaklv
elyrivvylgtslgnitrdqkilnpsalslhsklnatadilrgllsnvlcrlcskyhvgh
vdvtygpdtsgkdvfqkkklgcqllgkykqvisvlaqaf

Timeline for d1emra_:

• d1emra_ first appeared in SCOP 1.57
  
• d1emra_ appears in SCOP 1.73
  
• d1emra_ appears in SCOPe 2.01
  
• d1emra_ appears in the current release, SCOPe 2.08