Lineage for Class a: All alpha proteins

  1. Root: SCOP 1.67
  2. 349259Class a: All alpha proteins [46456] (202 folds)

Folds:

  1. 349260a.1: Globin-like [46457] (2 superfamilies)
    core: 6 helices; folded leaf, partly opened
  2. 350503a.2: Long alpha-hairpin [46556] (12 superfamilies)
    2 helices; antiparallel hairpin, left-handed twist
  3. 350824a.3: Cytochrome c [46625] (1 superfamily)
    core: 3 helices; folded leaf, opened
  4. 351236a.4: DNA/RNA-binding 3-helical bundle [46688] (12 superfamilies)
    core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
  5. 352395a.5: RuvA C-terminal domain-like [46928] (6 superfamilies)
    3 helices; bundle, right-handed twist
  6. 352497a.6: Putative DNA-binding domain [46954] (1 superfamily)
    core: 3 helices; architecture is similar to that of the "winged helix" fold but topology is different
  7. 352565a.7: Spectrin repeat-like [46965] (9 superfamilies)
    3 helices; bundle, closed, left-handed twist; up-and-down
  8. 352714a.8: immunoglobulin/albumin-binding domain-like [46996] (6 superfamilies)
    3 helices; bundle, closed, left-handed twist; up-and-down; mirror topology to the spectrin-like fold
  9. 352808a.9: Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex [47004] (1 superfamily)
    3 helices; bundle, closed, right-handed twist; up-and-down
  10. 352822a.10: Protozoan pheromone proteins [47013] (1 superfamily)
    3 helices; bundle, closed, left-handed twist, up-and-down
  11. 352841a.11: Acyl-CoA binding protein-like [47026] (2 superfamilies)
    core: 3 helices; bundle, closed, left-handed twist; up-and-down
  12. 352892a.12: Kix domain of CBP (creb binding protein) [47039] (1 superfamily)
    3 helices; bundle, partly opened
  13. 352899a.13: alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 [47044] (1 superfamily)
    3 helices, the first one is shorter than the other two; bundle, partly opened
  14. 352908a.14: VHP, Villin headpiece domain [47049] (1 superfamily)
    3 short helices; irregular array
  15. 352921a.15: TAF(II)230 TBP-binding fragment [47054] (1 superfamily)
    3 short helices; irregular array
  16. 352927a.16: S15/NS1 RNA-binding domain [47059] (1 superfamily)
    3 helices; irregular array
  17. 352970a.17: p8-MTCP1 [47071] (1 superfamily)
    3 helices; irregular array; disulfide-rich
  18. 352977a.18: T4 endonuclease V [47076] (1 superfamily)
    3 helices; irregular array
  19. 352987a.19: Fertilization protein [47081] (1 superfamily)
    core: 3 helices; bundle, closed, right-handed twist; up-and-down
  20. 353006a.20: PGBD-like [47089] (1 superfamily)
    core: 3 helices; bundle, closed, left-handed twist; parallel
  21. 353028a.21: HMG-box [47094] (1 superfamily)
    3 helices; irregular array
  22. 353075a.22: Histone-fold [47112] (1 superfamily)
    core: 3 helices; long middle helix is flanked at each end with shorter ones
  23. 353350a.23: Open three-helical up-and-down bundle [47143] (5 superfamilies)
    core: 3 helices; bundle, open
  24. 353428a.24: Four-helical up-and-down bundle [47161] (20 superfamilies)
    core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down
  25. 353826a.25: Ferritin-like [47239] (2 superfamilies)
    core: 4 helices; bundle, closed, left-handed twist; 1 crossover connection
  26. 354365a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  27. 354589a.27: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47322] (1 superfamily)
    core: 4 helices; bundle; one loop crosses over one side of the bundle
  28. 354640a.28: Acyl carrier protein-like [47335] (3 superfamilies)
    4 helices, bundle; helix 3 is shorter than others; up-and-down
  29. 354724a.29: Bromodomain-like [47363] (5 superfamilies)
    4 helices; bundle; minor mirror variant of up-and-down topology
  30. 354822a.30: ROP-like [47379] (4 superfamilies)
    4 helices; dimer of identical alpha-hairpin subunits; bundle, closed, left-handed twist
  31. 354870a.31: Dimerization-anchoring domain of cAMP-dependent type II PK regulatory subunit [47390] (1 superfamily)
    4 helices; bundle, closed, right-handed twist
  32. 354879a.32: Transcription factor IIA (TFIIA), alpha-helical domain [47395] (1 superfamily)
    4 helices; bundle, closed, right-handed twist
  33. 354894a.33: Ectatomin subunits [47400] (1 superfamily)
    4 helices; bundle, closed, left-handed twist
  34. 354903a.34: Dimerisation interlock [47405] (3 superfamilies)
    4 helices; bundle, closed, right-handed twist
  35. 354938a.35: lambda repressor-like DNA-binding domains [47412] (1 superfamily)
    core: 4 helices; folded leaf, closed
  36. 355094a.36: Signal peptide-binding domain [47445] (1 superfamily)
    4 helices; orthogonal array
  37. 355117a.37: A DNA-binding domain in eukaryotic transcription factors [47453] (1 superfamily)
    4 helices; the long C-terminal helix protrudes from the domain and binds to DNA
  38. 355126a.38: HLH-like [47458] (2 superfamilies)
    4-helices; bundle, closed, left-handed twist; 2 crossover connections
  39. 355182a.39: EF Hand-like [47472] (4 superfamilies)
    core: 4 helices; array of 2 hairpins, opened
  40. 355790a.40: CH domain-like [47575] (2 superfamilies)
    core: 4 helices: bundle
  41. 355838a.41: Domain of poly(ADP-ribose) polymerase [47586] (1 superfamily)
    core: 4 helices: bundle; unusual topology
  42. 355856a.42: SWIB/MDM2 domain [47591] (1 superfamily)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
  43. 355873a.43: Ribbon-helix-helix [47597] (1 superfamily)
    core: 4 helices; array of 2 hairpins, opened
  44. 355982a.45: Glutathione S-transferase (GST), C-terminal domain [47615] (1 superfamily)
    core: 4 helices; bundle, closed, left-handed twist; right-handed superhelix
  45. 356383a.46: Methionine synthase domain-like [47643] (2 superfamilies)
    4 helices; bundle, left-handed twist; right-handed superhelix
  46. 356427a.47: STAT-like [47654] (2 superfamilies)
    4 long helices; bundle, left-handed twist (coiled coil); right-handed superhelix
  47. 356462a.48: N-cbl like [47667] (3 superfamilies)
    4 helices; bundle, left-handed twist; left-handed superhelix
  48. 356492a.49: C-terminal domain of B transposition protein [47680] (1 superfamily)
    4 helices; irregular array
  49. 356498a.50: Anaphylotoxins (complement system) [47685] (1 superfamily)
    4 helices; irregular array, disulfide-linked
  50. 356507a.51: Cytochrome c oxidase subunit h [47693] (1 superfamily)
    4 helices; irregular array, disulfide-linked
  51. 356526a.52: Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [47698] (1 superfamily)
    4 helices; folded leaf; right-handed superhelix
  52. 356586a.53: p53 tetramerization domain [47718] (1 superfamily)
    core: 4 helices; bundle
  53. 356649a.54: Domain of early E2A DNA-binding protein, ADDBP [47723] (1 superfamily)
    4 helices; bundle, partly opened
  54. 356660a.55: IHF-like DNA-binding proteins [47728] (1 superfamily)
    core: 4 helices; bundle, partly opened, capped with a beta-sheet
  55. 356706a.56: CO dehydrogenase ISP C-domain like [47740] (1 superfamily)
    core: 4 helices, bundle
  56. 356748a.57: Protein HNS-dependent expression A; HdeA [47751] (1 superfamily)
    4 helices; the three last helices form a bundle similar to that of the RuvA C-domain
  57. 356762a.58: Chemotaxis receptor methyltransferase CheR, N-terminal domain [47756] (1 superfamily)
    4 helices; an orthogonal array
  58. 356769a.59: PAH2 domain [47761] (1 superfamily)
    4 helices; open up-and-down bundle; binds alpha-helical peptides
  59. 356779a.60: SAM domain-like [47768] (13 superfamilies)
    4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins
  60. 357284a.61: Retroviral matrix proteins [47835] (1 superfamily)
    4-5 helices; right-handed superhelix
  61. 357327a.62: Hepatitis B viral capsid (hbcag) [47851] (1 superfamily)
    5 helices; array; two long helices form a hairpin that dimerizes into a 4-helical bundle
  62. 357336a.63: Apolipophorin-III [47856] (1 superfamily)
    5 helices; bundle, closed, left-handed twist
  63. 357345a.64: Saposin-like [47861] (2 superfamilies)
    5 helices; folded leaf, closed
  64. 357388a.65: Annexin [47873] (1 superfamily)
    5 helices; folded leaf, closed
  65. 357469a.66: Transducin (alpha subunit), insertion domain [47894] (1 superfamily)
    5 helices; folded leaf
  66. 357513a.68: Wiscott-Aldrich syndrome protein, WASP, C-terminal domain [47911] (1 superfamily)
    5 helices; irregular array; left-handed superhelix
  67. 357519a.69: Left-handed superhelix [47916] (3 superfamilies)
    core: 4-5 helices; bundle; left-handed superhelix
  68. 357621a.70: N-terminal domain of the delta subunit of the F1F0-ATP synthase [47927] (1 superfamily)
    core: 5 helices; bundle
  69. 357627a.71: ERP29 C domain-like [47932] (2 superfamilies)
    5 helices; bundle
  70. 357650a.72: Functional domain of the splicing factor Prp18 [47937] (1 superfamily)
    core: 5 helices; bundle
  71. 357657a.73: Retrovirus capsid protein, N-terminal core domain [47942] (1 superfamily)
    core: 5 helices; bundle
  72. 357700a.74: Cyclin-like [47953] (1 superfamily)
    core: 5 helices; one helix is surrounded by the others
  73. 357870a.75: Ribosomal protein S7 [47972] (1 superfamily)
    core: 5 helices; contains one more helix and a beta-hairpin outside the core
  74. 357894a.76: Iron-dependent repressor protein, dimerization domain [47978] (1 superfamily)
    6 helices, homodimer of 3-helical domains
  75. 357940a.77: DEATH domain [47985] (1 superfamily)
    6 helices: closed bundle; greek-key; internal pseudo twofold symmetry
  76. 358000a.78: Fatty acid responsive transcription factor FadR, C-terminal domain [48007] (1 superfamily)
    core: 6 helices: closed bundle; greek-key; internal pseudo twofold symmetry
  77. 358013a.79: NusB-like [48012] (1 superfamily)
    6 helices: bundle; one central helix is surrounded by 5 others
  78. 358026a.80: DNA polymerase III clamp loader subunits, C-terminal domain [48018] (1 superfamily)
    core: 5 helices: bundle
  79. 358051a.81: N-terminal domain of DnaB helicase [48023] (1 superfamily)
    6 helices: array
  80. 358061a.83: Guanido kinase N-terminal domain [48033] (1 superfamily)
    irregular array of 6 short helices
  81. 358104a.84: Scaffolding protein gpD of bacteriophage procapsid [48044] (1 superfamily)
    core: 6 helices; one central helix is surrounded by 5 others
  82. 358117a.85: Hemocyanin, N-terminal domain [48049] (1 superfamily)
    6 helices; bundle; one central helix is surrounded by 5 others
  83. 358134a.86: Di-copper centre-containing domain [48055] (1 superfamily)
    multihelical
  84. 358169a.87: DBL homology domain (DH-domain) [48064] (1 superfamily)
    multihelical; core: 5-helical bundle
  85. 358201a.88: LigA subunit of an aromatic-ring-opening dioxygenase LigAB [48075] (1 superfamily)
    multihelical; contains compact array of 6 short helices
  86. 358210a.89: Methyl-coenzyme M reductase alpha and beta chain C-terminal domain [48080] (1 superfamily)
    multihelical bundle; contains buried central helix
  87. 358249a.90: Transcription factor STAT-4 N-domain [48091] (1 superfamily)
    multihelical; can be divided into two subdomains
  88. 358255a.91: Regulator of G-protein signaling, RGS [48096] (1 superfamily)
    multihelical; consists of two all-alpha subdomains
    contains a 4-helical bundle with left-handed twist and up-and-down topology
  89. 358287a.92: Carbamoyl phosphate synthetase, large subunit connection domain [48107] (1 superfamily)
    multihelical; consists of two all-alpha subdomains
    possible duplication: subdomains have similar topologies
  90. 358328a.93: Heme-dependent peroxidases [48112] (1 superfamily)
    multihelical; consists of two all-alpha domains
  91. 358614a.94: Ribosomal protein L19 (L19e) [48139] (1 superfamily)
    multihelical; consists of two different 3-helical domains connected by a long, partly helical linker
  92. 358637a.95: Influenza virus matrix protein M1 [48144] (1 superfamily)
    multihelical; consists of two different all-alpha subdomains, 4 helices each
  93. 358646a.96: DNA-glycosylase [48149] (1 superfamily)
    multihelical; consists of two all-alpha domains
  94. 358714a.97: An anticodon-binding domain of class I aminoacyl-tRNA synthetases [48162] (1 superfamily)
    multihelical; consists of two all-alpha domains
  95. 358733a.98: R1 subunit of ribonucleotide reductase, N-terminal domain [48167] (1 superfamily)
    multihelical consists of two all-alpha subdomains
    subdomain 1 (residues 10-100) is a 4-helical bundle
  96. 358760a.99: Cryptochrome/photolyase FAD-binding domain [48172] (1 superfamily)
    multihelical; consists of two all-alpha subdomains
  97. 358781a.100: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1 superfamily)
    multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry
  98. 358895a.101: Uteroglobin-like [48200] (1 superfamily)
    multihelical
  99. 358916a.102: alpha/alpha toroid [48207] (5 superfamilies)
    multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies
  100. 359292a.103: Citrate synthase [48255] (1 superfamily)
    multihelical; consists of two all-alpha domains
  101. 359341a.104: Cytochrome P450 [48263] (1 superfamily)
    multihelical
  102. 359523a.108: Ribosomal protein L7/12, oligomerisation (N-terminal) domain [48299] (1 superfamily)
    multihelical; intertwined tetramer
  103. 359543a.109: Class II MHC-associated invariant chain ectoplasmic trimerization domain [48304] (1 superfamily)
    multihelical; intertwined trimer of identical 3-helical subunits
  104. 359551a.110: Aldehyde ferredoxin oxidoreductase, C-terminal domains [48309] (1 superfamily)
    multihelical; consists of two all-alpha domains
  105. 359568a.111: Acid phosphatase/Vanadium-dependent haloperoxidase [48316] (1 superfamily)
    multihelical; core: 5-helical bundle; binds cofactor at the beginning of third helix
  106. 359612a.113: DNA repair protein MutS, domain III [48333] (1 superfamily)
    multihelical; consists of 2 all-alpha subdomains
  107. 359638a.114: Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain [48339] (1 superfamily)
    multihelical; bundle of longer and shorter helices
  108. 359645a.115: A virus capsid protein alpha-helical domain [48344] (1 superfamily)
    multihelical; three-helical bundle in the core is surrounded by non-conserved helices
  109. 359689a.116: GTPase activation domain, GAP [48349] (1 superfamily)
    multihelical
  110. 359719a.117: Ras GEF [48365] (1 superfamily)
    multihelical
  111. 359729a.118: alpha-alpha superhelix [48370] (20 superfamilies)
    multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix
  112. 360228a.119: Lipoxigenase [48483] (1 superfamily)
    multihelical
    large nearly all-alpha domain
  113. 360253a.120: gene 59 helicase assembly protein [48492] (1 superfamily)
    multihelical; consists of two all-alpha subdomains
  114. 360259a.121: Tetracyclin repressor-like, C-terminal domain [48497] (1 superfamily)
    multihelical; interlocked (homo)dimer
  115. 360318a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  116. 360580a.124: Phospholipase C/P1 nuclease [48536] (1 superfamily)
    multihelical
  117. 360609a.125: PDEase [48546] (1 superfamily)
    multihelical; can be divided into three subdomains
  118. 360670a.126: Serum albumin-like [48551] (1 superfamily)
    multihelical; one domain consists of two similar disulfide-linked subdomains
  119. 360794a.127: L-aspartase-like [48556] (1 superfamily)
    multihelical, consists of three all-alpha domains
  120. 360883a.128: Terpenoid synthases [48575] (1 superfamily)
    multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers
  121. 360967a.129: GroEL equatorial domain-like [48591] (1 superfamily)
    multihelical; 8 helices arranged in 2 parallel layers
  122. 361115a.130: Chorismate mutase II [48599] (1 superfamily)
    multihelical; core: 6 helices, bundle
  123. 361133a.131: Peridinin-chlorophyll protein [48607] (1 superfamily)
    multihelical: forms a boat-shaped protein shell around cofactors
  124. 361144a.132: Heme oxygenase-like [48612] (1 superfamily)
    multihelical; bundle
  125. 361220a.133: Phospholipase A2, PLA2 [48618] (1 superfamily)
    common core: 2 helices, disulfide-linked, and a calcium-binding loop
  126. 361479a.134: Fungal elicitin [48646] (1 superfamily)
    5 helices: irregular disulfide-linked array; also contains a small beta-hairpin
  127. 361492a.135: Tetraspanin [48651] (1 superfamily)
    5 helices: irregular disulfide-linked array; form homodimer
  128. 361501a.136: Repressor of bacterial conjugation FinO [48656] (1 superfamily)
    6 helices: irregular non-globular array; also contains two small b-hairpins
  129. 361507a.137: Non-globular all-alpha subunits of globular proteins [48661] (10 superfamilies)
    not a true fold
  130. 361613a.138: Multiheme cytochromes [48694] (1 superfamily)
    variable number of helices and little beta structure; not a true fold
  131. 361773a.139: Type I dockerin domain [63445] (1 superfamily)
    tandem repeat of two calcium-binding loop-helix motifs, distinct from the EF-hand
  132. 361783a.140: LEM/SAP HeH motif [63450] (4 superfamilies)
    helix-extended loop-helix; parallel helices
  133. 361839a.141: Frizzled cysteine-rich domain [63500] (1 superfamily)
    Core: 3 helices; irregular array; disulfide-rich
  134. 361854a.142: PTS-regulatory domain, PRD [63519] (1 superfamily)
    core: 4 helices; bundle, closed, right-handed twist; 1 crossover connection
  135. 361861a.143: RNA polymerase omega subunit [63561] (1 superfamily)
    4 helices; irregular array
  136. 361870a.144: PABP domain-like [63569] (2 superfamilies)
    4 helices; an orthogonal array
  137. 361890a.145: Flagellar transcriptional activator FlhD [63591] (1 superfamily)
    multihelical; forms intertwined dimer of identical 5-helical subunits
  138. 361897a.146: Telomeric repeat binding factor (TRF) dimerisation domain [63599] (1 superfamily)
    multihelical; can be divided into an alpha-alpha superhelix domain and a long alpha-hairpin dimerization domain
  139. 361907a.147: Bcr-Abl oncoprotein oligomerization domain [69035] (1 superfamily)
    core: 4 long helices; bundle
  140. 361920a.148: Arp2/3 complex 21 kDa subunit ARPC3 [69059] (1 superfamily)
    5 helices; one helix is surrounded by the others
  141. 361926a.149: RNase III endonuclease catalytic domain [69064] (1 superfamily)
    core: 5 helices; one helix is surrounded by the others
  142. 361945a.150: Anti-sigma factor AsiA [69069] (1 superfamily)
    core: 5 helices: orthogonal array
  143. 361954a.151: Glutamyl tRNA-reductase dimerization domain [69074] (1 superfamily)
    6 helices, homodimer of 3-helical domains
  144. 361960a.152: AhpD-like [69117] (1 superfamily)
    multihelical; contains 4-helical bundle and 2-helical arm
  145. 361995a.153: Nuclear receptor coactivator interlocking domain [69124] (1 superfamily)
    3 helices, non-globular array; forms interlocked heterodimers with its targets
  146. 362005a.154: Variable surface antigen VlsE [74747] (1 superfamily)
    multihelical; consists of two all-alpha subdomains; contains a 4-helical bundle with left-handed twist and up-and-down topology
  147. 362014a.155: H-NS histone-like proteins [81274] (1 superfamily)
    multihelical oligomeric protein; structure of whole subunit is not known yet but are probably composed of three different domains
  148. 362029a.156: S13-like H2TH domain [81297] (1 superfamily)
    core: 3-4 helices
  149. 362084a.157: Skp1 dimerisation domain-like [81384] (1 superfamily)
    multihelical; interlocked heterodimer with F-box proteins
  150. 362107a.158: F-box domain [81385] (1 superfamily)
    multihelical; interlocked heterodimer with the Skp1 dimerisation domain
  151. 362132a.159: Another 3-helical bundle [81602] (3 superfamilies)
    topologically similar to the DNA/RNA-binding bundles; distinct packing
  152. 362148a.160: PAP/OAS1 substrate-binding domain [81632] (1 superfamily)
    core: 5-helical bundle; up-and-down; right-handed twist
  153. 362172a.161: beta-catenin-interacting protein ICAT [81729] (1 superfamily)
    core: 3 helices; irregular array
  154. 362179a.162: Pre-protein crosslinking domain of SecA [81766] (1 superfamily)
    core: 4 helices: bundle; flanked by two short beta-hairpins
    duplication: consists of two structural repeats
  155. 362191a.163: Crustacean CHH/MIH/GIH neurohormone [81777] (1 superfamily)
    4 helices; irregular array, disulfide-linked
  156. 362197a.164: C-terminal domain of DFF45/ICAD (DFF-C domain) [81782] (1 superfamily)
    4 helices; folded leaf; right-handed superhelix
  157. 362204a.165: Myosin phosphatase inhibitor 17kDa protein, CPI-17 [81789] (1 superfamily)
    4 helices; open up-and-down bundle; flexible N-terminal tail
  158. 362212a.166: RuBisCo LSMT C-terminal, substrate-binding domain [81821] (1 superfamily)
    multihelical; irregular array of long and short helices
  159. 362226a.167: Porin chaperone SurA, peptide-binding domain [81826] (1 superfamily)
    multihelical; irregular array of long and short helices
  160. 362235a.168: GEF domain of SopE toxin [81831] (1 superfamily)
    multihelical; consists of two all-alpha subdomains each containing a 3-helical bundle with right-handed twist
  161. 362242a.169: BEACH domain [81836] (1 superfamily)
    multihelical, complex architecture
  162. 362249a.170: BRCA2 helical domain [81871] (1 superfamily)
    multihelical; contains a 3-helical bundle surrounded by several shorter helices
  163. 362259a.171: BRCA2 tower domain [81877] (1 superfamily)
    multihelical; contains a 3-helical Hin recombinase-like subdomain and two long dimerisation helices
  164. 362269a.172: Helical scaffold and wing domains of SecA [81885] (1 superfamily)
    multihelical; consists of 2 all-alpha subdomains
  165. 362281a.173: tRNA CCA-adding enzyme, C-terminal domains [81890] (1 superfamily)
    multihelical; can be divided into three subdomains (neck, body and tail)
  166. 362295a.174: Double Clp-N motif [81922] (1 superfamily)
    multihelical; array
  167. 362319a.175: Orange carotenoid protein, N-terminal domain [81929] (1 superfamily)
    multihelical; array
  168. 362326a.176: N-terminal domain of bifunctional PutA protein [81934] (1 superfamily)
    multihelical; array
  169. 362332a.177: Sigma2 domain of RNA polymerase sigma factors [88945] (1 superfamily)
    multihelical; consists of a conserved 4-helical core and a variable insert subdomain
  170. 362360a.178: Soluble domain of poliovirus core protein 3a [89042] (1 superfamily)
    4 helices; bundle, closed, right-handed twist
  171. 362367a.179: Replisome organizer (g39p helicase loader/inhibitor protein) [89063] (1 superfamily)
    4 helices; bundle, right-handed twist; left-handed superhelix
  172. 362375a.180: N-terminal, cytoplasmic domain of anti-sigmaE factor RseA [89068] (1 superfamily)
    4 helices; irregular array
  173. 362382a.181: Antibiotic binding domain of TipA-like multidrug resistance regulators [89081] (1 superfamily)
    5 helices: orthogonal array
  174. 362388a.182: GatB/YqeY domain [89094] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles (4-helical and 3-helical)
  175. 362394a.183: Nop domain [89123] (1 superfamily)
    multihelical; array of longer and shorter helices; contains an alpha-hairpin dimerisation subdomain
  176. 362400a.184: TorA specific chaperone TorD [89154] (1 superfamily)
    multihelical; bundle
  177. 362407a.185: Gametocyte protein Pfg27 [89161] (1 superfamily)
    multihelical; bundle
  178. 362413a.186: Circadian clock protein KaiA, C-terminal domain [101214] (1 superfamily)
    4 helices; bundle, right-handed twist; right-handed superhelix
  179. 362424a.187: HAND domain of the nucleosome remodeling ATPase ISWI [101223] (1 superfamily)
    4 helices; irregular array
  180. 362430a.188: PWI domain [101232] (1 superfamily)
    4 helices; up-and-down bundle; topological similarity to the bromodomain-like and SAM domain-like folds
  181. 362436a.189: XPC-binding domain of Rad23 homolog A (Hhr23a) [101237] (1 superfamily)
    4 helices; array
  182. 362443a.190: Flavivirus capsid protein C [101256] (1 superfamily)
    core: 5 helices; right-handed superhelix; swapped dimer with the two long C-terminal helices
  183. 362450a.191: Methenyltetrahydrofolate cyclohydrolase-like [101261] (1 superfamily)
    5 helices; bundle, closed, left-handed twist
  184. 362457a.192: N-terminal domain of adenylylcyclase associated protein, CAP [101277] (1 superfamily)
    6 helices: bundle; left-handed twist, up-and-down topology
  185. 362464a.193: GRIP domain [101282] (1 superfamily)
    6 helices, homodimer of 3-helical domains
  186. 362477a.194: L27 domain [101287] (1 superfamily)
    6 helices, heterodimer of 3-helical domains
  187. 362496a.195: YutG-like [101306] (1 superfamily)
    core: 6 helices; bundle; one central helix is surrounded by 5 others
  188. 362505a.196: Invasion protein A (SipA) , C-terminal actin binding domain [101311] (1 superfamily)
    6 helices: orthogonal array
  189. 362511a.197: Hypothetical protein Aq 328 [101316] (1 superfamily)
    core: 6 helices; one central helix is surrounded by 5 others
  190. 362517a.198: YcfC-like [101321] (1 superfamily)
    multihelical; contains two buried central helices
  191. 362523a.199: YgfB-like [101326] (1 superfamily)
    multihelical; consists of two tightly associated 3-helical bundles with different twists
  192. 362529a.200: Hypothetical protein MTH393 [101331] (1 superfamily)
    multihelical; consists of two all-alpha subdomains; dimer
  193. 362536a.201: HD domain [101338] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  194. 362543a.202: Superantigen MAM [101343] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  195. 362550a.203: Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) [101352] (1 superfamily)
    multihelical; consists of two all-alpha subdomains
  196. 362556a.204: Type II deoxyuridine triphosphatase [101385] (1 superfamily)
    multihelical; consists of 2 all-alpha subdomains, "rigid" one and "mobile" one
  197. 362566a.205: Hsp90 co-chaperone CDC37 [101390] (1 superfamily)
    multihelical; consists of 2 all-alpha subdomains connected by a long helix
  198. 362572a.206: P40 nucleoprotein [101398] (1 superfamily)
    multihelical; consists of two subdomains
  199. 362579a.207: Formin homology 2 domain (FH2 domain) [101446] (1 superfamily)
    multihelical, consists of three all-alpha domains
  200. 362593a.208: Citrobacter dihydroxyacetone kinase extra ATP-binding domain [101472] (1 superfamily)
    multihelical; bundle
  201. 362602a.209: ADP-ribosylglycohydrolase [101477] (1 superfamily)
    multihelical; bundle
  202. 362608a.210: Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domain [101488] (1 superfamily)
    5 helices, non-globular array; wraps around the N-terminal tail of its target

More info for Class a: All alpha proteins

Timeline for Class a: All alpha proteins: