SCOPe 2.08: Domain d1cz8w_: 1cz8 W:

Lineage for d1cz8w_ (1cz8 W:)

1. Root: SCOPe 2.08

2. Class g: Small proteins [56992] (100 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families)

5. Family g.17.1.1: Platelet-derived growth factor-like [57502] (4 proteins)

6. Protein Vascular endothelial growth factor, VEGF [57505] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57506] (22 PDB entries)
   Uniprot P15692 40-133

8. Domain d1cz8w_: 1cz8 W: [44766]
   Other proteins in same PDB: d1cz8h1, d1cz8h2, d1cz8l1, d1cz8l2, d1cz8x1, d1cz8x2, d1cz8y1, d1cz8y2
   complexed with so4

Details for d1cz8w_

PDB Entry: 1cz8, 2.4 Å

PDB Description: vascular endothelial growth factor in complex with an affinity matured antibody

PDB Compounds: (W:) Vascular Endothelial Growth Factor A

SCOPe Domain Sequences for d1cz8w_:

Sequence; same for both SEQRES and ATOM records:

>d1cz8w_ g.17.1.1 (W:) Vascular endothelial growth factor, VEGF {Human (Homo sapiens) [TaxId: 9606]}
vvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndeglecvptee
snitmqimrikphqgqhigemsflqhnkcecrpk

Timeline for d1cz8w_:

• d1cz8w_ first appeared (with stable ids) in SCOP 1.55
  
• d1cz8w_ appears in SCOPe 2.07