SCOPe 2.08: Family g.17.1.1: Platelet-derived growth factor-like

Lineage for Family g.17.1.1: Platelet-derived growth factor-like

1. Root: SCOPe 2.08

2. Class g: Small proteins [56992] (100 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families)

5. Family g.17.1.1: Platelet-derived growth factor-like [57502] (4 proteins)

Proteins:

1. Placenta growth factor-1, PLGF-1 [64560] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [64561] (2 PDB entries)

2. Platelet-derived growth factor BB [57503] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [57504] (1 PDB entry)

3. Vascular endothelial growth factor, VEGF [57505] (3 species)

   1. Species Aspic viper (Vipera aspis aspis) [TaxId:8706] [118255] (1 PDB entry)
      Uniprot P67863 1-100 # svVEGF (toxin); vammin

   2. Species Human (Homo sapiens) [TaxId:9606] [57506] (22 PDB entries)
      Uniprot P15692 40-133

   3. Species Russell's viper (Daboia russelli russelli) [TaxId:8707] [118256] (1 PDB entry)
      Uniprot P67861 2-95 # svVEGF (toxin); VR-1

4. automated matches [190290] (1 species)
   not a true protein

   • Species Human (Homo sapiens) [TaxId:9606] [187095] (7 PDB entries)

More info for Family g.17.1.1: Platelet-derived growth factor-like

Timeline for Family g.17.1.1: Platelet-derived growth factor-like:

• Family g.17.1.1: Platelet-derived growth factor-like first appeared (with stable ids) in SCOP 1.55
  
• Family g.17.1.1: Platelet-derived growth factor-like appears in SCOPe 2.07