SCOP 1.63: Domain d1rne__: 1rne -

Lineage for d1rne__ (1rne -)

1. Root: SCOP 1.63

2. Class b: All beta proteins [48724] (119 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.2: Pepsin-like [50646] (9 proteins)
   duplication: consists of two similar barrel domains
   N-terminal: barrel, partly opened; n*=6, S*=10

6. Protein Chymosin (synonim: renin) [50667] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50669] (6 PDB entries)

8. Domain d1rne__: 1rne - [26871]
   complexed with c60, nag

Details for d1rne__

PDB Entry: 1rne, 2.4 Å

PDB Description: the crystal structure of recombinant glycosylated human renin alone and in complex with a transition state analog inhibitor

SCOP Domain Sequences for d1rne__:

Sequence, based on SEQRES records:

>d1rne__ b.50.1.2 (-) Chymosin (synonim: renin) {Human (Homo sapiens)}
nttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyhklf
dasdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmlaef
dgvvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdsensqslggqivlggsdpq
hyegnfhyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklme
algakkrlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaihamd
ippptgptwalgatfirkfytefdrrnnrigfalar

Sequence, based on observed residues (ATOM records):

>d1rne__ b.50.1.2 (-) Chymosin (synonim: renin) {Human (Homo sapiens)}
nttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyhklf
dasdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmlaef
dgvvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdlggqivlggsdpqhyegnf
hyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklmealgakk
rlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaihamdippptg
ptwalgatfirkfytefdrrnnrigfalar

Timeline for d1rne__:

• d1rne__ first appeared (with stable ids) in SCOP 1.55
  
• d1rne__ appears in SCOP 1.61
  
• d1rne__ appears in SCOP 1.65
  
• d1rne__ appears in the current release, SCOPe 2.08, called d1rnea_