SCOPe 2.07: Domain d3py8a2: 3py8 A:423-832

Lineage for d3py8a2 (3py8 A:423-832)

1. Root: SCOPe 2.07

2. Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.1: DNA polymerase I [56673] (5 proteins)

6. Protein DNA polymerase I (Klenow fragment) [56674] (3 species)

7. Species Thermus aquaticus [TaxId:271] [56676] (29 PDB entries)

8. Domain d3py8a2: 3py8 A:423-832 [265234]
   Other proteins in same PDB: d3py8a1
   automated match to d3rrha2
   protein/DNA complex; complexed with dct, gol, mg, mn; mutant

Details for d3py8a2

PDB Entry: 3py8, 1.74 Å

PDB Description: Crystal structure of a mutant of the large fragment of DNA polymerase I from thermus aquaticus in a closed ternary complex with DNA and ddCTP

PDB Compounds: (A:) DNA polymerase I

SCOPe Domain Sequences for d3py8a2:

Sequence; same for both SEQRES and ATOM records:

>d3py8a2 e.8.1.1 (A:423-832) DNA polymerase I (Klenow fragment) {Thermus aquaticus [TaxId: 271]}
eerllwlyreverplsavlahmeatgvrldvaylralslevaeeiarleaevfrlaghpf
nlnsrdqlervlfdelglpaigktektgkrstsaavlealreahpivekilqyreltklk
styidplpdlihprtgrlhtrfnqtatatgrlsssdpnlqnipvrtplgqrirrafiaee
gwllvaldysqkelrvlahlsgdenlirvfqegrdihtetaswmfgvpreavdplmrraa
ktinfgvlygmsahrlsqelaipyeeaqafieryfqsfpkvrawiektleegrrrgyvet
lfgrrryvpdlearvksvreaaerkafnmpvqgtaadlmklamvklfprleemgarmllq
vhdelvleapkeraeavarlakevmegvyplavplevevgigedwlsake

Timeline for d3py8a2:

• d3py8a2 first appeared in SCOPe 2.05
  
• d3py8a2 appears in SCOPe 2.06
  
• d3py8a2 appears in the current release, SCOPe 2.08