Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds) |
Fold e.8: DNA/RNA polymerases [56671] (1 superfamily) divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members |
Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families) "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain |
Family e.8.1.1: DNA polymerase I [56673] (5 proteins) |
Protein DNA polymerase I (Klenow fragment) [56674] (3 species) |
Bacillus stearothermophilus, newly identified strain as yet unnamed [TaxId:1422] [56677] (44 PDB entries) Uniprot Q5KWC1 299-878 # 99% sequence identity; Geobacillus kaustophilus TaxID:1462 Uniprot Q45458 298-876 # 88% sequence identity |
Domain d1l3sa2: 1l3s A:469-876 [84522] Other proteins in same PDB: d1l3sa1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1l3ta2: 1l3t A:469-876 [84524] Other proteins in same PDB: d1l3ta1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1l3ua2: 1l3u A:469-876 [84526] Other proteins in same PDB: d1l3ua1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1l3va2: 1l3v A:469-876 [84528] Other proteins in same PDB: d1l3va1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1l5ua2: 1l5u A:469-876 [84530] Other proteins in same PDB: d1l5ua1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1lv5a2: 1lv5 A:469-876 [84720] Other proteins in same PDB: d1lv5a1, d1lv5b1 protein/DNA complex; complexed with dcp, mg, mn, so4 |
Domain d1lv5b2: 1lv5 B:469-876 [84722] Other proteins in same PDB: d1lv5a1, d1lv5b1 protein/DNA complex; complexed with dcp, mg, mn, so4 |
Domain d1njwa2: 1njw A:469-876 [91914] Other proteins in same PDB: d1njwa1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1njxa2: 1njx A:469-876 [91916] Other proteins in same PDB: d1njxa1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1njya2: 1njy A:469-876 [91918] Other proteins in same PDB: d1njya1 protein/DNA complex; complexed with mg, so4, suc, ttp |
Domain d1njza2: 1njz A:469-876 [91920] Other proteins in same PDB: d1njza1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1nk0a2: 1nk0 A:469-876 [91922] Other proteins in same PDB: d1nk0a1 protein/DNA complex; complexed with mes, so4, suc |
Domain d1nk4a2: 1nk4 A:469-876 [91924] Other proteins in same PDB: d1nk4a1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1nk5a2: 1nk5 A:469-876 [91926] Other proteins in same PDB: d1nk5a1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1nk6a2: 1nk6 A:469-876 [91928] Other proteins in same PDB: d1nk6a1 protein/DNA complex; complexed with so4, suc |
Domain d1nk7a2: 1nk7 A:469-876 [91930] Other proteins in same PDB: d1nk7a1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1nk8a2: 1nk8 A:469-876 [91932] Other proteins in same PDB: d1nk8a1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1nk9a2: 1nk9 A:469-876 [91934] Other proteins in same PDB: d1nk9a1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1nkba2: 1nkb A:469-876 [91936] Other proteins in same PDB: d1nkba1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1nkca2: 1nkc A:469-876 [91938] Other proteins in same PDB: d1nkca1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1nkea2: 1nke A:469-876 [91940] Other proteins in same PDB: d1nkea1 protein/DNA complex; complexed with dcp, mg, so4, suc |
Domain d1u45a2: 1u45 A:469-876 [107655] Other proteins in same PDB: d1u45a1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1u47a2: 1u47 A:469-876 [107659] Other proteins in same PDB: d1u47a1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1u48a2: 1u48 A:469-876 [107661] Other proteins in same PDB: d1u48a1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1u49a2: 1u49 A:469-876 [107663] Other proteins in same PDB: d1u49a1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1u4ba2: 1u4b A:469-876 [107665] Other proteins in same PDB: d1u4ba1 protein/DNA complex; complexed with mg, so4, suc |
Domain d1ua0a2: 1ua0 A:469-876 [107754] Other proteins in same PDB: d1ua0a1 protein/DNA complex; complexed with af, so4, suc |
Domain d1ua1a2: 1ua1 A:469-876 [107756] Other proteins in same PDB: d1ua1a1 protein/DNA complex; complexed with af, so4 |
Domain d1xc9a2: 1xc9 A:469-876 [115112] Other proteins in same PDB: d1xc9a1 protein/DNA complex; complexed with bap, mg, so4, suc |
Domain d1xwla2: 1xwl A:469-876 [43001] Other proteins in same PDB: d1xwla1 complexed with so4 |
Domain d2bdpa2: 2bdp A:469-876 [43002] Other proteins in same PDB: d2bdpa1 protein/DNA complex; complexed with mg, so4 |
Domain d2hhqa2: 2hhq A:469-876 [136507] Other proteins in same PDB: d2hhqa1 automatically matched to d1l3sa2 protein/DNA complex; complexed with mg, so4, suc |
Domain d2hhsa2: 2hhs A:469-876 [136509] Other proteins in same PDB: d2hhsa1 automatically matched to d1l3sa2 protein/DNA complex; complexed with mg, so4, suc |
Domain d2hhta2: 2hht A:469-876 [136511] Other proteins in same PDB: d2hhta1 automatically matched to d1l3sa2 protein/DNA complex; complexed with mg, so4, suc |
Domain d2hhua2: 2hhu A:469-876 [136513] Other proteins in same PDB: d2hhua1 automatically matched to d1l3sa2 protein/DNA complex; complexed with dcp, mg, so4, suc |
Domain d2hhva2: 2hhv A:469-876 [136515] Other proteins in same PDB: d2hhva1 automatically matched to d1l3sa2 protein/DNA complex; complexed with mg, so4, suc |
Domain d2hhwa2: 2hhw A:469-876 [136517] Other proteins in same PDB: d2hhwa1, d2hhwd1 automatically matched to d1l3sa2 protein/DNA complex; complexed with 23t, mn, so4, suc |
Domain d2hhwd2: 2hhw D:469-876 [136519] Other proteins in same PDB: d2hhwa1, d2hhwd1 automatically matched to d1l3sa2 protein/DNA complex; complexed with 23t, mn, so4, suc |
Domain d2hhxa2: 2hhx A:469-876 [136521] Other proteins in same PDB: d2hhxa1 automatically matched to d1l3sa2 protein/DNA complex; complexed with so4, suc |
Domain d2hvha2: 2hvh A:469-876 [136805] Other proteins in same PDB: d2hvha1, d2hvhd1 protein/DNA complex; complexed with dct, mn, so4, suc |
Domain d2hvhd2: 2hvh D:469-876 [136807] Other proteins in same PDB: d2hvha1, d2hvhd1 protein/DNA complex; complexed with dct, mn, so4, suc |
Domain d2hvia2: 2hvi A:469-876 [136809] Other proteins in same PDB: d2hvia1, d2hvid1 protein/DNA complex; complexed with dct, mg, so4, suc |
Domain d2hvid2: 2hvi D:469-876 [136811] Other proteins in same PDB: d2hvia1, d2hvid1 protein/DNA complex; complexed with dct, mg, so4, suc |
Domain d2hw3a2: 2hw3 A:469-876 [136820] Other proteins in same PDB: d2hw3a1 automated match to d4dqqa2 protein/DNA complex; complexed with mg, so4, suc |
Domain d3bdpa2: 3bdp A:469-876 [43004] Other proteins in same PDB: d3bdpa1 protein/DNA complex; complexed with so4 |
Domain d3eyza2: 3eyz A:469-876 [232128] Other proteins in same PDB: d3eyza1 automated match to d2hhva2 protein/DNA complex; complexed with so4, suc |
Domain d3ez5a2: 3ez5 A:469-876 [232130] Other proteins in same PDB: d3ez5a1, d3ez5d1 automated match to d2hvia2 protein/DNA complex; complexed with dad, so4, suc, zn |
Domain d3ez5d2: 3ez5 D:469-876 [232132] Other proteins in same PDB: d3ez5a1, d3ez5d1 automated match to d2hvia2 protein/DNA complex; complexed with dad, so4, suc, zn |
Domain d4bdpa2: 4bdp A:469-876 [43003] Other proteins in same PDB: d4bdpa1 protein/DNA complex; complexed with mg, so4 |
Escherichia coli [TaxId:562] [56675] (14 PDB entries) |
Domain d1d8ya2: 1d8y A:519-928 [42977] Other proteins in same PDB: d1d8ya1 protein/DNA complex; complexed with so4, zn |
Domain d1d9da2: 1d9d A:519-928 [42981] Other proteins in same PDB: d1d9da1 protein/DNA complex; protein/RNA complex; complexed with mg, so4, zn |
Domain d1d9fa2: 1d9f A:519-928 [42984] Other proteins in same PDB: d1d9fa1 protein/DNA complex; protein/RNA complex; complexed with so4, zn |
Domain d1dpia2: 1dpi A:519-928 [42985] Other proteins in same PDB: d1dpia1 protein/DNA complex; complexed with zn |
Domain d1kfda2: 1kfd A:519-928 [42987] Other proteins in same PDB: d1kfda1 protein/DNA complex; complexed with ctp |
Domain d1kfsa2: 1kfs A:519-928 [42974] Other proteins in same PDB: d1kfsa1 protein/DNA complex; complexed with mg, zn; mutant |
Domain d1klna2: 1kln A:519-928 [42986] Other proteins in same PDB: d1klna1 protein/DNA complex; complexed with zn; mutant |
Domain d1krpa2: 1krp A:519-928 [42978] Other proteins in same PDB: d1krpa1 protein/DNA complex; complexed with zn; mutant |
Domain d1kspa2: 1ksp A:519-928 [42980] Other proteins in same PDB: d1kspa1 protein/DNA complex; complexed with zn; mutant |
Domain d1qsla2: 1qsl A:519-928 [42979] Other proteins in same PDB: d1qsla1 protein/DNA complex; complexed with eu |
Domain d2kfna2: 2kfn A:519-928 [42975] Other proteins in same PDB: d2kfna1 protein/DNA complex; complexed with mg, mn, zn |
Domain d2kfza2: 2kfz A:519-928 [42976] Other proteins in same PDB: d2kfza1 protein/DNA complex; complexed with mg, zn |
Domain d2kzma2: 2kzm A:519-928 [42983] Other proteins in same PDB: d2kzma1 protein/DNA complex; complexed with mn, zn |
Domain d2kzza2: 2kzz A:519-928 [42982] Other proteins in same PDB: d2kzza1 protein/DNA complex; complexed with zn |
Thermus aquaticus [TaxId:271] [56676] (29 PDB entries) |
Domain d1cmwa8: 1cmw A:423-832 [302291] Other proteins in same PDB: d1cmwa5, d1cmwa6, d1cmwa7 automated match to d1bgxt4 |
Domain d1jxea2: 1jxe A:423-832 [42998] Other proteins in same PDB: d1jxea1 |
Domain d1ktqa2: 1ktq A:423-832 [42996] Other proteins in same PDB: d1ktqa1 |
Domain d1qssa2: 1qss A:423-831 [42990] Other proteins in same PDB: d1qssa1 protein/DNA complex; complexed with dg3, mg |
Domain d1qsya2: 1qsy A:423-831 [42993] Other proteins in same PDB: d1qsya1 protein/DNA complex; complexed with dds, mg |
Domain d1qtma2: 1qtm A:423-831 [42988] Other proteins in same PDB: d1qtma1 protein/DNA complex; complexed with mg, ttp |
Domain d1taqa4: 1taq A:423-832 [42991] Other proteins in same PDB: d1taqa1, d1taqa2, d1taqa3 complexed with bgl, zn |
Domain d1taua4: 1tau A:423-832 [43000] Other proteins in same PDB: d1taua1, d1taua2, d1taua3 protein/DNA complex; complexed with bgl, zn |
Domain d2ktqa2: 2ktq A:423-832 [42995] Other proteins in same PDB: d2ktqa1 protein/DNA complex; complexed with dct, mg |
Domain d3ktqa2: 3ktq A:423-831 [42989] Other proteins in same PDB: d3ktqa1 protein/DNA complex; complexed with dct, mg |
Domain d3m8ra2: 3m8r A:423-832 [213154] Other proteins in same PDB: d3m8ra1 automated match to d1jxea2 protein/DNA complex; complexed with 15p, act, gol, hxz, mg |
Domain d3m8sa2: 3m8s A:423-832 [213156] Other proteins in same PDB: d3m8sa1 automated match to d1jxea2 protein/DNA complex; complexed with 15p, act, gol, hxb, mg, peg |
Domain d3ojua2: 3oju A:423-832 [214398] Other proteins in same PDB: d3ojua1 automated match to d1jxea2 protein/DNA complex; complexed with gol, mg, pge, ssj |
Domain d3py8a2: 3py8 A:423-832 [265234] Other proteins in same PDB: d3py8a1 automated match to d3rrha2 protein/DNA complex; complexed with dct, gol, mg, mn; mutant |
Domain d3rr7a2: 3rr7 A:423-832 [216008] Other proteins in same PDB: d3rr7a1 automated match to d1jxea2 protein/DNA complex; complexed with fmt, gol, mg |
Domain d3rr8a2: 3rr8 A:423-832 [216010] Other proteins in same PDB: d3rr8a1 automated match to d1jxea2 protein/DNA complex; complexed with dg3, gol |
Domain d3rrga2: 3rrg A:423-832 [216018] Other proteins in same PDB: d3rrga1 automated match to d1jxea2 protein/DNA complex; complexed with act, dg3, gol, na |
Domain d3rrha2: 3rrh A:423-832 [216020] Other proteins in same PDB: d3rrha1 automated match to d1jxea2 protein/DNA complex; complexed with act, gol, mg, pge, ttp |
Domain d3rtva2: 3rtv A:423-832 [216067] Other proteins in same PDB: d3rtva1 automated match to d1jxea2 protein/DNA complex; complexed with act, dcp, gol, mg |
Domain d3t3fa2: 3t3f A:423-832 [216657] Other proteins in same PDB: d3t3fa1 automated match to d1jxea2 protein/DNA complex; complexed with fmt, gol, mg, n5p, na |
Domain d4df4a2: 4df4 A:423-832 [219734] Other proteins in same PDB: d4df4a1 automated match to d1jxea2 protein/DNA complex; complexed with 0l3, edo, mg |
Domain d4dfpa2: 4dfp A:423-832 [219741] Other proteins in same PDB: d4dfpa1 automated match to d1jxea2 protein/DNA complex; complexed with 0l7, edo, fmt, mg |
Domain d4dlea2: 4dle A:423-832 [266156] Other proteins in same PDB: d4dlea1 automated match to d3rrha2 protein/DNA complex; complexed with dct, edo, gol, mg, mn |
Domain d4dlga2: 4dlg A:423-832 [219846] Other proteins in same PDB: d4dlga1 automated match to d1jxea2 protein/DNA complex; complexed with act, dct, gol, mg |
Domain d4ktqa2: 4ktq A:423-832 [42999] Other proteins in same PDB: d4ktqa1 protein/DNA complex |
Domain d4n56a2: 4n56 A:423-832 [307750] Other proteins in same PDB: d4n56a1 automated match to d3rrha2 protein/DNA complex; complexed with gol, mg, mn; mutant |
Domain d4n5sa2: 4n5s A:423-831 [307752] Other proteins in same PDB: d4n5sa1 automated match to d3rrha2 protein/DNA complex; complexed with act, dct, epe, gol, mg, mn; mutant |
Domain d5ktqa2: 5ktq A:423-832 [42997] Other proteins in same PDB: d5ktqa1 complexed with dcp |
Timeline for Protein DNA polymerase I (Klenow fragment) from e.8.1.1: DNA polymerase I: