Lineage for Superfamily e.8.1: DNA/RNA polymerases

  1. Root: SCOPe 2.07
  2. 2618030Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)
  3. 2622069Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 2622070Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain


  1. 2622071e.8.1.1: DNA polymerase I [56673] (5 proteins)
  2. 2622423e.8.1.2: Reverse transcriptase [56686] (3 proteins)
  3. 2622993e.8.1.3: T7 RNA polymerase [56691] (2 proteins)
  4. 2623022e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)
  5. 2623647e.8.1.6: dsRNA phage RNA-dependent RNA-polymerase [64480] (1 protein)
    automatically mapped to Pfam PF00680
  6. 2623694e.8.1.7: Lesion bypass DNA polymerase (Y-family), catalytic domain [100888] (5 proteins)
    contains a distinct 'fingers' domain possibly related to the C-terminal subdomain of hypothetical protein Ta1206 (1qw2)
  7. 2623852e.8.1.8: Splicing factor Prp8 RT domain [345981] (2 proteins)
    Pfam PF10598, Pfam PF10597. Includes linker domain discussed in PubMed 23354046
    Homology to retroviral RT domains discussed in PubMed 21441348
  8. 2623861e.8.1.0: automated matches [227142] (1 protein)
    not a true family

More info for Superfamily e.8.1: DNA/RNA polymerases

Timeline for Superfamily e.8.1: DNA/RNA polymerases: