SCOPe 2.08: Domain d4ir3a1: 4ir3 A:1858-1971

Lineage for d4ir3a1 (4ir3 A:1858-1971)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (15 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (1052 PDB entries)

8. Domain d4ir3a1: 4ir3 A:1858-1971 [223328]
   Other proteins in same PDB: d4ir3a2
   automated match to d2nxbb_
   complexed with 1fk, edo, gol

Details for d4ir3a1

PDB Entry: 4ir3, 2 Å

PDB Description: crystal structure of the bromodomain of human baz2b in complex with 1- [7-amino-1-(pyrimidin-2-yl)indolizin-3-yl]ethanone (gsk2833282a)

PDB Compounds: (A:) Bromodomain adjacent to zinc finger domain protein 2B

SCOPe Domain Sequences for d4ir3a1:

Sequence; same for both SEQRES and ATOM records:

>d4ir3a1 a.29.2.0 (A:1858-1971) automated matches {Human (Homo sapiens) [TaxId: 9606]}
svkkpkrddskdlalcsmiltemethedawpfllpvnlklvpgykkvikkpmdfstirek
lssgqypnletfaldvrlvfdncetfneddsdigraghnmrkyfekkwtdtfkv

Timeline for d4ir3a1:

• d4ir3a1 first appeared in SCOPe 2.03, called d4ir3a_
  
• d4ir3a1 appears in SCOPe 2.07