SCOPe 2.08: Protein: Nsp15, C-terminal domain

Lineage for Protein: Nsp15, C-terminal domain

Root: SCOPe 2.08
Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
Fold d.294: EndoU-like [142876] (1 superfamily)
comprises several helices and two three-stranded antiparallel beta-sheets; similar architecture to the RNase A-like fold (54075)

Superfamily d.294.1: EndoU-like [142877] (3 families)

similarity to the RNase A-like superfamily (54076) extends to the active site location and architecture; the two structural cores of the RNase A and EndoU superfamilies are interrelated by a topological permutation - transposition of two pereferial beta-strands, suggesting possible distant homology of the two superfamilies (and their unification in a hyperfamily)

Family d.294.1.2: Nsp15 C-terminal domain-like [142881] (2 proteins)
PfamB PB001946
Protein Nsp15, C-terminal domain [142882] (2 species)

Species:

Murine hepatitis virus, MHV [TaxId:11138] [142884] (2 PDB entries)
Uniprot P16342 6720-6872
1. Domain for 2gth:
  - Domain d2gtha2: 2gth A:217-369 [135651]
    Other proteins in same PDB: d2gtha1, d2gtha3
2. Domain for 2gti:
  - Domain d2gtia2: 2gti A:217-369 [135653]
    Other proteins in same PDB: d2gtia1, d2gtia3
    complexed with gol, so4; mutant
SARS coronavirus [TaxId:227859] [142883] (3 PDB entries)
Uniprot Q6VA80 6620-6774
1. Domain for 2h85:
  - Domain d2h85a2: 2h85 A:191-345 [136234]
    Other proteins in same PDB: d2h85a1, d2h85a3
2. Domains for 2ozk:
  1. Domain d2ozka2: 2ozk A:191-332 [149108]
    Other proteins in same PDB: d2ozka1, d2ozkb1, d2ozkc1, d2ozkd1
  2. Domain d2ozkb2: 2ozk B:191-332 [149110]
    Other proteins in same PDB: d2ozka1, d2ozkb1, d2ozkc1, d2ozkd1
    automated match to d2ozka2
  3. Domain d2ozkc2: 2ozk C:191-332 [149112]
    Other proteins in same PDB: d2ozka1, d2ozkb1, d2ozkc1, d2ozkd1
    automated match to d2ozka2
  4. Domain d2ozkd2: 2ozk D:191-332 [149114]
    Other proteins in same PDB: d2ozka1, d2ozkb1, d2ozkc1, d2ozkd1
    automated match to d2ozka2
3. Domains for 2rhb:
  1. Domain d2rhba2: 2rhb A:191-344 [152037]
    Other proteins in same PDB: d2rhba1, d2rhba3, d2rhbb1, d2rhbb3, d2rhbc1, d2rhbc3, d2rhbd1, d2rhbd3, d2rhbe1, d2rhbe3, d2rhbf1
    automated match to d2h85a2
    mutant
  2. Domain d2rhbb2: 2rhb B:191-344 [152039]
    Other proteins in same PDB: d2rhba1, d2rhba3, d2rhbb1, d2rhbb3, d2rhbc1, d2rhbc3, d2rhbd1, d2rhbd3, d2rhbe1, d2rhbe3, d2rhbf1
    automated match to d2h85a2
    mutant
  3. Domain d2rhbc2: 2rhb C:191-344 [152041]
    Other proteins in same PDB: d2rhba1, d2rhba3, d2rhbb1, d2rhbb3, d2rhbc1, d2rhbc3, d2rhbd1, d2rhbd3, d2rhbe1, d2rhbe3, d2rhbf1
    automated match to d2h85a2
    mutant
  4. Domain d2rhbd2: 2rhb D:191-344 [152043]
    Other proteins in same PDB: d2rhba1, d2rhba3, d2rhbb1, d2rhbb3, d2rhbc1, d2rhbc3, d2rhbd1, d2rhbd3, d2rhbe1, d2rhbe3, d2rhbf1
    automated match to d2h85a2
    mutant
  5. Domain d2rhbe2: 2rhb E:191-344 [152045]
    Other proteins in same PDB: d2rhba1, d2rhba3, d2rhbb1, d2rhbb3, d2rhbc1, d2rhbc3, d2rhbd1, d2rhbd3, d2rhbe1, d2rhbe3, d2rhbf1
    automated match to d2h85a2
    mutant
  6. Domain d2rhbf2: 2rhb F:191-344 [152047]
    Other proteins in same PDB: d2rhba1, d2rhba3, d2rhbb1, d2rhbb3, d2rhbc1, d2rhbc3, d2rhbd1, d2rhbd3, d2rhbe1, d2rhbe3, d2rhbf1
    automated match to d2h85a2
    mutant

More info for Protein Nsp15, C-terminal domain from d.294.1.2: Nsp15 C-terminal domain-like

Timeline for Protein Nsp15, C-terminal domain from d.294.1.2: Nsp15 C-terminal domain-like:

Protein Nsp15, C-terminal domain from d.294.1.2: Nsp15 C-terminal domain-like first appeared in SCOP 1.73
Protein Nsp15, C-terminal domain from d.294.1.2: Nsp15 C-terminal domain-like appears in SCOPe 2.07