Lineage for d2gtia1 (2gti A:1-194)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2892669Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
  4. 2892670Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (61 families) (S)
  5. 2894145Family c.66.1.48: Nsp15 N-terminal domain-like [142625] (2 proteins)
    rudiment methyltransferase fold that probably has lost the enzymatic activity; contains extra N-terminal alpha+beta subdomain
  6. 2894146Protein Nsp15 [142626] (2 species)
  7. 2894147Species Murine hepatitis virus, MHV [TaxId:11138] [142627] (2 PDB entries)
    Uniprot P16342 6504-6697! Uniprot P16342 6697-6872
  8. 2894148Domain d2gtia1: 2gti A:1-194 [135652]
    Other proteins in same PDB: d2gtia2, d2gtia3
    complexed with gol, so4; mutant

Details for d2gtia1

PDB Entry: 2gti (more details), 2.15 Å

PDB Description: mutation of mhv coronavirus non-structural protein nsp15 (f307l)
PDB Compounds: (A:) Replicase polyprotein 1ab

SCOPe Domain Sequences for d2gtia1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2gtia1 c.66.1.48 (A:1-194) Nsp15 {Murine hepatitis virus, MHV [TaxId: 11138]}
slenvvynlvnaghfdgragelpcavigekviakiqnedvvvfknntpfptnvavelfak
rsirphpelklfrnlnidvcwshvlwdyakdsvfcsstykvckytdlqcieslnvlfdgr
dngaleafkkcrngvyinttkikslsmikgpqradlngvvvekvgdsdvefwfavrkdgd
dvifsrtgslepsh

SCOPe Domain Coordinates for d2gtia1:

Click to download the PDB-style file with coordinates for d2gtia1.
(The format of our PDB-style files is described here.)

Timeline for d2gtia1: