SCOP 1.73: Protein: Nsp15, C-terminal domain

Lineage for Protein: Nsp15, C-terminal domain

Root: SCOP 1.73
Class d: Alpha and beta proteins (a+b) [53931] (334 folds)
Fold d.294: EndoU-like [142876] (1 superfamily)
comprises several helices and two three-stranded antiparallel beta-sheets; similar architecture to the RNase A-like fold (scop_cf 54075)

Superfamily d.294.1: EndoU-like [142877] (2 families)

similarity to the RNase A-like superfamily (scop_sf 54076) extends to the active site location and architecture; the two structural cores of the RNase A and EndoU superfamilies are interrelated by a topological permutation - transposition of two pereferial beta-strands, suggesting possible distant homology of the two superfamilies (and their unification in a hyperfamily)

Family d.294.1.2: Nsp15 C-terminal domain-like [142881] (1 protein)
PfamB 001946
Protein Nsp15, C-terminal domain [142882] (2 species)

Species:

Murine hepatitis virus, MHV [TaxId:11138] [142884] (2 PDB entries)
1. Domain for 2gth:
  - Domain d2gtha2: 2gth A:217-369 [135651]
    Other proteins in same PDB: d2gtha1
2. Domain for 2gti:
  - Domain d2gtia2: 2gti A:217-369 [135653]
    Other proteins in same PDB: d2gtia1
    complexed with gol, so4; mutant
SARS coronavirus [TaxId:227859] [142883] (1 PDB entry)
- Domain for 2h85:
  - Domain d2h85a2: 2h85 A:191-345 [136234]
    Other proteins in same PDB: d2h85a1
    mutant

More info for Protein Nsp15, C-terminal domain from d.294.1.2: Nsp15 C-terminal domain-like

Timeline for Protein Nsp15, C-terminal domain from d.294.1.2: Nsp15 C-terminal domain-like:

Protein Nsp15, C-terminal domain from d.294.1.2: Nsp15 C-terminal domain-like is new in SCOP 1.73
Protein Nsp15, C-terminal domain from d.294.1.2: Nsp15 C-terminal domain-like appears in SCOP 1.75
Protein Nsp15, C-terminal domain from d.294.1.2: Nsp15 C-terminal domain-like appears in the current release, SCOPe 2.08