|  | Class a: All alpha proteins [46456] (289 folds) | 
|  | Fold a.60: SAM domain-like [47768] (16 superfamilies) 4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins | 
|  | Superfamily a.60.2: RuvA domain 2-like [47781] (7 families)  duplication: contains two helix-hairpin-helix (HhH) motifs | 
|  | Family a.60.2.5: Hef domain-like [140629] (4 proteins) helicase/nuclease domain; forms homo and heterodimers; probably includes the Excinuclease UvrC C-terminal domain ((81795), that contains a single NMR structure of a monomeric truncated domain, 1kft) | 
|  | Protein DNA excision repair protein ERCC-1 [140630] (1 species) | 
|  | Species Human (Homo sapiens) [TaxId:9606] [140631] (3 PDB entries) Uniprot P07992 219-296! Uniprot P07992 220-297 | 
|  | Domain d1z00a1: 1z00 A:220-297 [124294] Other proteins in same PDB: d1z00a2, d1z00b1 | 
|  | Domain d2a1jb1: 2a1j B:220-296 [126001] Other proteins in same PDB: d2a1ja1, d2a1jb2 protein/DNA complex; complexed with hg | 
|  | Domain d2muta1: 2mut A:220-297 [274219] Other proteins in same PDB: d2muta2, d2muta3, d2mutb_ automated match to d1z00a1 mutant | 
Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.60.2.5 DNA excision repair protein ERCC-1: