SCOPe 2.08: Domain d2fakt_: 2fak T:

Lineage for d2fakt_ (2fak T:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
   4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing

4. Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families)
   N-terminal residue provides two catalytic groups, nucleophile and proton donor

5. Family d.153.1.4: Proteasome subunits [56251] (4 proteins)

6. Protein Proteasome alpha subunit (non-catalytic) [56255] (10 species)
   contains an extension to the common fold at the N-terminus

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56257] (240 PDB entries)
   The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)

8. Domain d2fakt_: 2fak T: [133216]
   Other proteins in same PDB: d2fak1_, d2fak2_, d2fakd_, d2fakg_, d2fakh_, d2faki_, d2fakj_, d2fakk_, d2fakl_, d2fakm_, d2fakn_, d2fakr_, d2faku_, d2fakv_, d2fakw_, d2fakx_, d2faky_, d2fakz_
   automated match to d1g65f_
   complexed with sa1

Details for d2fakt_

PDB Entry: 2fak, 2.8 Å

PDB Description: Crystal structure of Salinosporamide A in complex with the yeast 20S proteasome

PDB Compounds: (T:) Proteasome component C1

SCOPe Domain Sequences for d2fakt_:

Sequence; same for both SEQRES and ATOM records:

>d2fakt_ d.153.1.4 (T:) Proteasome alpha subunit (non-catalytic) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
gtgydlsnsvfspdgrnfqveyavkavengttsigikcndgvvfaveklitskllvpqkn
vkiqvvdrhigcvysglipdgrhlvnrgreeaasfkklyktpipipafadrlgqyvqaht
lynsvrpfgvstifggvdkngahlymlepsgsywgykgaatgkgrqsakaeleklvdhhp
eglsareavkqaakiiylahednkekdfeleiswcslsetnglhkfvkgdllqeaidfaq
kein

Timeline for d2fakt_:

• d2fakt_ first appeared in SCOP 1.73, called d2fakt1
  
• d2fakt_ appears in SCOPe 2.07