SCOP 1.73: Domain d2egha2: 2egh A:0-125,A:275-300

Lineage for d2egha2 (2egh A:0-125,A:275-300)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (22 proteins)
   family members also share a common alpha+beta fold in C-terminal domain

6. Protein 1-deoxy-D-xylulose-5-phosphate reductoisomerase [69410] (2 species)

7. Species Escherichia coli [TaxId:562] [69411] (11 PDB entries)

8. Domain d2egha2: 2egh A:0-125,A:275-300 [132122]
   Other proteins in same PDB: d2egha1, d2egha3, d2eghb1, d2eghb3
   automatically matched to d1jvsa2
   complexed with fom, mg, ndp

Details for d2egha2

PDB Entry: 2egh, 2.2 Å

PDB Description: Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase complexed with a magnesium ion, NADPH and fosmidomycin

PDB Compounds: (A:) 1-deoxy-D-xylulose 5-phosphate reductoisomerase

SCOP Domain Sequences for d2egha2:

Sequence; same for both SEQRES and ATOM records:

>d2egha2 c.2.1.3 (A:0-125,A:275-300) 1-deoxy-D-xylulose-5-phosphate reductoisomerase {Escherichia coli [TaxId: 562]}
gkqltilgstgsigcstldvvrhnpehfrvvalvagknvtrmveqclefspryavmddea
sakllktmlqqqgsrtevlsgqqaacdmaaledvdqvmaaivgaagllptlaairagkti
llankeXmrtpiahtmawpnrvnsgvkpldfck

Timeline for d2egha2:

• d2egha2 is new in SCOP 1.73
  
• d2egha2 appears in SCOP 1.75
  
• d2egha2 appears in the current release, SCOPe 2.08