SCOP 1.73: Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain

Lineage for Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (22 proteins)
   family members also share a common alpha+beta fold in C-terminal domain

Proteins:

1. 1-deoxy-D-xylulose-5-phosphate reductoisomerase [69410] (2 species)

   1. Species Escherichia coli [TaxId:562] [69411] (11 PDB entries)

   2. Species Zymomonas mobilis [TaxId:542] [110420] (2 PDB entries)

2. Acetaldehyde dehydrogenase (acylating) [89527] (1 species)

   • Species Pseudomonas sp. [TaxId:306] [89528] (1 PDB entry)

3. Aspartate beta-semialdehyde dehydrogenase [51813] (4 species)

   1. Species Escherichia coli [TaxId:562] [51814] (4 PDB entries)

   2. Species Haemophilus influenzae [TaxId:727] [102159] (12 PDB entries)

   3. Species Streptococcus pneumoniae [TaxId:1313] [141917] (4 PDB entries)

   4. Species Vibrio cholerae [TaxId:666] [82297] (2 PDB entries)

4. Biliverdin reductase [51823] (1 species)

   • Species Rat (Rattus norvegicus) [TaxId:10116] [51824] (3 PDB entries)

5. Diaminopimelic acid dehydrogenase (DAPDH) [51819] (1 species)

   • Species Corynebacterium glutamicum [TaxId:1718] [51820] (4 PDB entries)

6. Dihydrodipicolinate reductase [51821] (3 species)

   1. Species Escherichia coli [TaxId:562] [51822] (5 PDB entries)

   2. Species Mycobacterium tuberculosis [TaxId:1773] [102160] (5 PDB entries)

   3. Species Thermotoga maritima [TaxId:2336] [110417] (1 PDB entry)

7. Galactose/lactose metabolism regulatory protein GAL80 [141921] (1 species)

   • Species Yeast (Kluyveromyces lactis) [TaxId:28985] [141922] (1 PDB entry)

8. Glucose 6-phosphate dehydrogenase, N-terminal domain [51827] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [51829] (1 PDB entry)

   2. Species Leuconostoc mesenteroides [TaxId:1245] [51828] (9 PDB entries)

9. Glucose-fructose oxidoreductase, N-terminal domain [51825] (1 species)

   • Species Zymomonas mobilis [TaxId:542] [51826] (8 PDB entries)

10. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) [51801] (18 species)

    1. Species Achromobacter xylosoxidans [TaxId:85698] [89526] (1 PDB entry)
       formerly Alcaligenes xylosoxidans

    2. Species American lobster (Homarus americanus) [TaxId:6706] [51810] (2 PDB entries)

    3. Species Archaeon Methanothermus fervidus [TaxId:2180] [51807] (1 PDB entry)

    4. Species Archaeon Sulfolobus solfataricus [TaxId:2287] [51806] (1 PDB entry)

    5. Species Bacillus stearothermophilus, nca 1503 [TaxId:1422] [51803] (10 PDB entries)

    6. Species Escherichia coli [TaxId:562] [51802] (7 PDB entries)

    7. Species Human (Homo sapiens) [TaxId:9606] [51812] (1 PDB entry)

    8. Species Human(Homo sapiens), liver isoform [TaxId:9606] [141915] (2 PDB entries)

    9. Species Leishmania mexicana [TaxId:5665] [51809] (5 PDB entries)

    10. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [141916] (3 PDB entries)

    11. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [102158] (1 PDB entry)

    12. Species South China Sea lobster (Palinurus versicolor) [TaxId:82835] [51811] (5 PDB entries)

    13. Species Spinach (Spinacia oleracea) [TaxId:3562] [69409] (8 PDB entries)

    14. Species Thermotoga maritima [TaxId:2336] [51805] (1 PDB entry)

    15. Species Thermus aquaticus [TaxId:271] [51804] (2 PDB entries)

    16. Species Thermus thermophilus [TaxId:274] [102157] (1 PDB entry)

    17. Species Trypanosoma brucei brucei, glycosome [TaxId:5702] [51808] (1 PDB entry)

    18. Species Trypanosoma cruzi [TaxId:5693] [75104] (3 PDB entries)

11. Homoserine dehydrogenase [51815] (1 species)

    • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [51816] (4 PDB entries)

12. Hypothetical protein TM0312 [141925] (1 species)

    • Species Thermotoga maritima [TaxId:2336] [141926] (1 PDB entry)

13. Hypothetical protein TM1419 [102161] (1 species)
    myo-inositol 1-phosphate synthase-related protein

    • Species Thermotoga maritima [TaxId:2336] [102162] (1 PDB entry)

14. Hypothetical protein TM1643 [75108] (1 species)

    • Species Thermotoga maritima [TaxId:2336] [75109] (2 PDB entries)

15. Myo-inositol 1-phosphate synthase [75105] (4 species)

    1. Species Archaeoglobus fulgidus [TaxId:2234] [110418] (1 PDB entry)

    2. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [75107] (9 PDB entries)

    3. Species Caenorhabditis elegans [TaxId:6239] [110419] (1 PDB entry)

    4. Species Mycobacterium tuberculosis [TaxId:1773] [75106] (1 PDB entry)

16. N-acetyl-gamma-glutamyl-phosphate reductase ArgC [110423] (3 species)

    1. Species Salmonella typhimurium [TaxId:90371] [141918] (1 PDB entry)

    2. Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [117428] (2 PDB entries)

    3. Species Thermotoga maritima [TaxId:2336] [110424] (1 PDB entry)

17. Probable oxidoreductase At4g09670 [117429] (1 species)

    • Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [117430] (1 PDB entry)

18. Putative oxidoreductase VCA1048 [110425] (1 species)

    • Species Vibrio cholerae [TaxId:666] [110426] (1 PDB entry)

19. Putative semialdehyde dehydrogenase [141919] (1 species)

    • Species Rice (Oryza sativa) [TaxId:4530] [141920] (1 PDB entry)

20. Saccharopine reductase [51817] (1 species)

    • Species Rice blast fungus (Magnaporthe grisea) [TaxId:148305] [51818] (3 PDB entries)

21. Usg-1 protein homolog PA3116 [141923] (1 species)

    • Species Pseudomonas aeruginosa [TaxId:287] [141924] (1 PDB entry)

22. Virulence factor MviM [110421] (1 species)

    • Species Escherichia coli [TaxId:562] [110422] (1 PDB entry)

More info for Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain

Timeline for Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain:

• Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain first appeared (with stable ids) in SCOP 1.55
  
• Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain appears in SCOP 1.71
  
• Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain appears in SCOP 1.75
  
• Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain appears in the current release, SCOPe 2.08