Lineage for d2ccha2 (2cch A:1-296)

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. Species Human (Homo sapiens) [TaxId:9606] [88856] (414 PDB entries)
    Uniprot P24941
  8. Domain d2ccha2: 2cch A:1-296 [130236]
    Other proteins in same PDB: d2ccha3, d2cchb1, d2cchb2, d2cchc3, d2cchd1, d2cchd2
    automated match to d1aq1__
    complexed with atp, gol, so4

Details for d2ccha2

PDB Entry: 2cch (more details), 1.7000000000000002 Å

PDB Description: the crystal structure of cdk2 cyclin a in complex with a substrate peptide derived from cdc modified with a gamma-linked atp analogue
PDB Compounds: (A:) Cell division protein kinase 2

SCOPe Domain Sequences for d2ccha2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2ccha2 d.144.1.7 (A:1-296) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl

SCOPe Domain Coordinates for d2ccha2 are not available.

Timeline for d2ccha2:

View in 3D
Domains from same chain:
(mouse over for more information)
d2ccha3
View in 3D
Domains from other chains:
(mouse over for more information)
d2cchb1, d2cchb2, d2cchc2, d2cchc3, d2cchd1, d2cchd2