SCOPe 2.08: Domain d2cchb2: 2cch B:309-432

Lineage for d2cchb2 (2cch B:309-432)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.74: Cyclin-like [47953] (1 superfamily)
   core: 5 helices; one helix is surrounded by the others

4. Superfamily a.74.1: Cyclin-like [47954] (4 families)
   duplication: consists of two domains of this fold

5. Family a.74.1.1: Cyclin [47955] (9 proteins)

6. Protein Cyclin A [47956] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [47957] (89 PDB entries)
   Uniprot P20248 175-432

8. Domain d2cchb2: 2cch B:309-432 [130238]
   Other proteins in same PDB: d2ccha2, d2ccha3, d2cchc2, d2cchc3
   automatically matched to d1vin_2
   complexed with atp, gol, so4

Details for d2cchb2

PDB Entry: 2cch, 1.7 Å

PDB Description: the crystal structure of cdk2 cyclin a in complex with a substrate peptide derived from cdc modified with a gamma-linked atp analogue

PDB Compounds: (B:) cyclin a2

SCOPe Domain Sequences for d2cchb2:

Sequence; same for both SEQRES and ATOM records:

>d2cchb2 a.74.1.1 (B:309-432) Cyclin A {Human (Homo sapiens) [TaxId: 9606]}
ptvnqfltqyflhqqpanckveslamflgelslidadpylkylpsviagaafhlalytvt
gqswpeslirktgytleslkpclmdlhqtylkapqhaqqsirekyknskyhgvsllnppe
tlnl

Timeline for d2cchb2:

• d2cchb2 first appeared in SCOP 1.73
  
• d2cchb2 appears in SCOPe 2.07