PDB entry 2cch
View 2cch on RCSB PDB site
Description: The crystal structure of CDK2 cyclin A in complex with a substrate peptide derived from CDC modified with a gamma-linked ATP analogue
Class: cell cycle
Keywords: complex(transferase-cell division), ATP-binding, cdk2, cell cycle, cell division, cyclin, mitosis, nuclear protein, peptide specificity, phosphorylation, polymorphism, protein kinase, recruitment, serine-threonine-protein kinase, serine/threonine-protein kinase, transferase
Deposited on
2006-01-16, released
2006-05-03
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-02-27, with a file datestamp of
2019-02-22.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cell division protein kinase 2
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 2CCH (0-0)
- Uniprot P24941 (1-End)
Domains in SCOPe 2.08: d2ccha2, d2ccha3 - Chain 'B':
Compound: cyclin a2
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2cchb1, d2cchb2 - Chain 'C':
Compound: Cell division protein kinase 2
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 2CCH (0-0)
- Uniprot P24941 (1-End)
Domains in SCOPe 2.08: d2cchc2, d2cchc3 - Chain 'D':
Compound: cyclin a2
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2cchd1, d2cchd2 - Chain 'E':
Compound: cell division control protein 6 homolog
Species: HOMO SAPIENS, synthetic [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'F':
Compound: cell division control protein 6 homolog
Species: HOMO SAPIENS, synthetic [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Heterogens: ATP, SO4, GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2cchA (A:)
smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps
fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
Sequence, based on observed residues (ATOM records): (download)
>2cchA (A:)
smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps
fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>2cchB (B:)
nevpdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetl
hlavnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkqvl
rmehlvlkvltfdlaaptvnqfltqyflhqqpanckveslamflgelslidadpylkylp
sviagaafhlalytvtgqswpeslirktgytleslkpclmdlhqtylkapqhaqqsirek
yknskyhgvsllnppetlnl
- Chain 'C':
Sequence, based on SEQRES records: (download)
>2cchC (C:)
smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps
fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
Sequence, based on observed residues (ATOM records): (download)
>2cchC (C:)
smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps
fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl
- Chain 'D':
Sequence, based on SEQRES records: (download)
>2cchD (D:)
nevpdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetl
hlavnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkqvl
rmehlvlkvltfdlaaptvnqfltqyflhqqpanckveslamflgelslidadpylkylp
sviagaafhlalytvtgqswpeslirktgytleslkpclmdlhqtylkapqhaqqsirek
yknskyhgvsllnppetlnl
Sequence, based on observed residues (ATOM records): (download)
>2cchD (D:)
pdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetlhla
vnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkqvlrme
hlvlkvltfdlaaptvnqfltqyflhqqpanckveslamflgelslidadpylkylpsvi
agaafhlalytvtgqswpeslirktgytleslkpclmdlhqtylkapqhaqqsirekykn
skyhgvsllnppetln
- Chain 'E':
No sequence available.
- Chain 'F':
No sequence available.