SCOP 1.73: Protein: Thymidine kinase, TK1, N-terminal domain

Lineage for Protein: Thymidine kinase, TK1, N-terminal domain

Root: SCOP 1.73
Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (24 families)
division into families based on beta-sheet topologies

Family c.37.1.24: Type II thymidine kinase [117558] (1 protein)
N-terminal part of Pfam PF00265; parallel beta-sheet of 6 strands, order 324516; topological similarity to the RecA-like proteins, especially CobA (scop_pr 52684)

Protein Thymidine kinase, TK1, N-terminal domain [117559] (3 species)

Species:

Clostridium acetobutylicum [TaxId:1488] [117562] (1 PDB entry)
- Domains for 1xx6:
  1. Domain d1xx6a1: 1xx6 A:2-142 [116139]
    Other proteins in same PDB: d1xx6a2, d1xx6b2
  2. Domain d1xx6b1: 1xx6 B:2-142 [116141]
    Other proteins in same PDB: d1xx6a2, d1xx6b2
    Structural genomics target
    complexed with adp, zn
Human (Homo sapiens) [TaxId:9606] [117560] (2 PDB entries)
1. Domains for 1xbt:
  1. Domain d1xbta1: 1xbt A:18-150 [115080]
    Other proteins in same PDB: d1xbta2, d1xbtb2, d1xbtc2, d1xbtd2, d1xbte2, d1xbtf2, d1xbtg2, d1xbth2
  2. Domain d1xbtb1: 1xbt B:18-150 [115082]
    Other proteins in same PDB: d1xbta2, d1xbtb2, d1xbtc2, d1xbtd2, d1xbte2, d1xbtf2, d1xbtg2, d1xbth2
  3. Domain d1xbtc1: 1xbt C:18-150 [115084]
    Other proteins in same PDB: d1xbta2, d1xbtb2, d1xbtc2, d1xbtd2, d1xbte2, d1xbtf2, d1xbtg2, d1xbth2
  4. Domain d1xbtd1: 1xbt D:18-150 [115086]
    Other proteins in same PDB: d1xbta2, d1xbtb2, d1xbtc2, d1xbtd2, d1xbte2, d1xbtf2, d1xbtg2, d1xbth2
  5. Domain d1xbte1: 1xbt E:18-150 [115088]
    Other proteins in same PDB: d1xbta2, d1xbtb2, d1xbtc2, d1xbtd2, d1xbte2, d1xbtf2, d1xbtg2, d1xbth2
  6. Domain d1xbtf1: 1xbt F:18-150 [115090]
    Other proteins in same PDB: d1xbta2, d1xbtb2, d1xbtc2, d1xbtd2, d1xbte2, d1xbtf2, d1xbtg2, d1xbth2
  7. Domain d1xbtg1: 1xbt G:18-150 [115092]
    Other proteins in same PDB: d1xbta2, d1xbtb2, d1xbtc2, d1xbtd2, d1xbte2, d1xbtf2, d1xbtg2, d1xbth2
  8. Domain d1xbth1: 1xbt H:18-150 [115094]
    Other proteins in same PDB: d1xbta2, d1xbtb2, d1xbtc2, d1xbtd2, d1xbte2, d1xbtf2, d1xbtg2, d1xbth2
    complexed with mg, ttp, zn; mutant
2. Domains for 2orv:
  1. Domain d2orva1: 2orv A:18-150 [139274]
    Other proteins in same PDB: d2orva2, d2orvb2
    automatically matched to d1xbta1
    complexed with 4ta, zn; mutant
  2. Domain d2orvb1: 2orv B:18-150 [139276]
    Other proteins in same PDB: d2orva2, d2orvb2
    automatically matched to d1xbta1
    complexed with 4ta, zn; mutant
Ureaplasma urealyticum [TaxId:2130] [117561] (2 PDB entries)
1. Domains for 2b8t:
  1. Domain d2b8ta1: 2b8t A:11-149 [128109]
    Other proteins in same PDB: d2b8ta2, d2b8tb2, d2b8tc2, d2b8td2
    complexed with thm, trs, zn
  2. Domain d2b8tb1: 2b8t B:11-149 [128111]
    Other proteins in same PDB: d2b8ta2, d2b8tb2, d2b8tc2, d2b8td2
    automatically matched to 2B8T A:11-149
    complexed with thm, trs, zn
  3. Domain d2b8tc1: 2b8t C:11-149 [128113]
    Other proteins in same PDB: d2b8ta2, d2b8tb2, d2b8tc2, d2b8td2
    automatically matched to 2B8T A:11-149
    complexed with thm, trs, zn
  4. Domain d2b8td1: 2b8t D:12-149 [128115]
    Other proteins in same PDB: d2b8ta2, d2b8tb2, d2b8tc2, d2b8td2
    automatically matched to 2B8T A:11-149
    complexed with thm, trs, zn
2. Domains for 2uz3:
  1. Domain d2uz3a1: 2uz3 A:11-149 [140040]
    Other proteins in same PDB: d2uz3a2, d2uz3b2, d2uz3c2, d2uz3d2
    automatically matched to d1xmra1
    complexed with mg, ttp, zn; mutant
  2. Domain d2uz3b1: 2uz3 B:11-149 [140042]
    Other proteins in same PDB: d2uz3a2, d2uz3b2, d2uz3c2, d2uz3d2
    automatically matched to d1xmra1
    complexed with mg, ttp, zn; mutant
  3. Domain d2uz3c1: 2uz3 C:11-149 [140044]
    Other proteins in same PDB: d2uz3a2, d2uz3b2, d2uz3c2, d2uz3d2
    automatically matched to d1xmra1
    complexed with mg, ttp, zn; mutant
  4. Domain d2uz3d1: 2uz3 D:11-149 [140046]
    Other proteins in same PDB: d2uz3a2, d2uz3b2, d2uz3c2, d2uz3d2
    automatically matched to d1xmra1
    complexed with mg, ttp, zn; mutant

More info for Protein Thymidine kinase, TK1, N-terminal domain from c.37.1.24: Type II thymidine kinase

Timeline for Protein Thymidine kinase, TK1, N-terminal domain from c.37.1.24: Type II thymidine kinase:

Protein Thymidine kinase, TK1, N-terminal domain from c.37.1.24: Type II thymidine kinase first appeared in SCOP 1.71
Protein Thymidine kinase, TK1, N-terminal domain from c.37.1.24: Type II thymidine kinase appears in SCOP 1.75
Protein Thymidine kinase, TK1, N-terminal domain from c.37.1.24: Type II thymidine kinase appears in the current release, SCOPe 2.08